Food-derived sensory cues modulate longevity via distinct neuroendocrine insulin-like peptides

C. elegans lifespan extension by osmotic stress requires FUdR, base excision repair, FOXO, and sirtuins

(2016) Edward N. Anderson et al.   MECHANISMS OF AGEING AND DEVELOPMENT

SREBP and MDT-15 protectC. elegansfrom glucose-induced accelerated aging by preventing accumulation of saturated fat

(2015) Dongyeop Lee et al.   GENES & DEVELOPMENT

Sensory systems: their impact on C. elegans survival

(2015) E.N. Allen et al.   NEUROSCIENCE

RNA helicase HEL-1 promotes longevity by specifically activating DAF-16/FOXO transcription factor signaling inCaenorhabditis elegans

(2015) Mihwa Seo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TRPV1 Pain Receptors Regulate Longevity and Metabolism by Neuropeptide Signaling

(2014) Céline E. Riera et al.   CELL

Nucleolar GTPase NOG-1 Regulates Development, Fat Storage, and Longevity through Insulin/IGF Signaling in C. elegans

(2014) Young-Il Kim et al.   MOLECULES AND CELLS

Positive and negative gustatory inputs affect Drosophila lifespan partly in parallel to dFOXO signaling

(2014) I. Ostojic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Water sensor ppk28 modulates Drosophila lifespan and physiology through AKH signaling

(2014) M. J. Waterson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Insulin-to-Insulin Regulatory Network Orchestrates Phenotypic Specificity in Development and Physiology

(2014) Diana Andrea Fernandes de Abreu et al.   PLoS Genetics

Direct and Indirect Gene Regulation by a Life-Extending FOXO Protein in C. elegans: Roles for GATA Factors and Lipid Gene Regulators

(2013) Peichuan Zhang et al.   Cell Metabolism

Complex expression dynamics and robustness in C. elegans insulin networks

(2013) A. D. Ritter et al.   GENOME RESEARCH

Two Insulin-like Peptides Antagonistically Regulate Aversive Olfactory Learning in C. elegans

(2013) Zhunan Chen et al.   NEURON

Drosophila insulin-like peptide-6 (dilp6) expression from fat body extends lifespan and represses secretion of Drosophila insulin-like peptide-2 from the brain

(2012) Hua Bai et al.   AGING CELL

Neuromodulation of Neuronal Circuits: Back to the Future

(2012) Eve Marder   NEURON

Genes That Act Downstream of Sensory Neurons to Influence Longevity, Dauer Formation, and Pathogen Responses in Caenorhabditis elegans

(2012) Marta M. Gaglia et al.   PLoS Genetics

Specific insulin-like peptides encode sensory information to regulate distinct developmental processes

(2011) A. Cornils et al.   DEVELOPMENT

OASIS: Online Application for the Survival Analysis of Lifespan Assays Performed in Aging Research

(2011) Jae-Seong Yang et al.   PLoS One

Inhibition of Respiration Extends C. elegans Life Span via Reactive Oxygen Species that Increase HIF-1 Activity

(2010) Seung-Jae Lee et al.   CURRENT BIOLOGY

Carbon Dioxide Sensing Modulates Lifespan and Physiology in Drosophila

(2010) Peter C. Poon et al.   PLOS BIOLOGY

A Neuromedin U Receptor Acts with the Sensory System to Modulate Food Type-Dependent Effects on C. elegans Lifespan

(2010) Wolfgang Maier et al.   PLOS BIOLOGY

Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways inC. elegans

(2009) Eric L. Greer et al.   AGING CELL

The Modulation of Lifespan by Perceptual Systems

(2009) Scott D. Pletcher   Annals of the New York Academy of Sciences

Regulation of the Longevity Response to Temperature by Thermosensory Neurons in Caenorhabditis elegans

(2009) Seung-Jae Lee et al.   CURRENT BIOLOGY

Optimizing Dietary Restriction for Genetic Epistasis Analysis and Gene Discovery in C. elegans

(2009) William Mair et al.   PLoS One

Age- and calorie-independent life span extension from dietary restriction by bacterial deprivation in Caenorhabditis elegans

(2008) Erica D Smith et al.   BMC DEVELOPMENTAL BIOLOGY