DREADDs suppress seizure-like activity in a mouse model of pharmacoresistant epileptic brain tissue

The First Structure–Activity Relationship Studies for Designer Receptors Exclusively Activated by Designer Drugs

(2015) Xin Chen et al.   ACS Chemical Neuroscience

DREADDs (Designer Receptors Exclusively Activated by Designer Drugs): Chemogenetic Tools with Therapeutic Utility

(2015) Daniel J. Urban et al.   Annual Review of Pharmacology and Toxicology

Differential Effect of Neuropeptides on Excitatory Synaptic Transmission in Human Epileptic Hippocampus

(2015) M. Ledri et al.   JOURNAL OF NEUROSCIENCE

Drug Resistance in Cortical and Hippocampal Slices from Resected Tissue of Epilepsy Patients: No Significant Impact of P-Glycoprotein and Multidrug Resistance-Associated Proteins

(2015) Nora Sandow et al.   Frontiers in Neurology

An organotypic brain slice preparation from adult patients with temporal lobe epilepsy

(2014) Emmanuel Eugène et al.   JOURNAL OF NEUROSCIENCE METHODS

Optogenetic inhibition of chemically induced hypersynchronized bursting in mice

(2014) Fredrik Berglind et al.   NEUROBIOLOGY OF DISEASE

Optogenetics Reveal Delayed Afferent Synaptogenesis on Grafted Human-Induced Pluripotent Stem Cell-Derived Neural Progenitors

(2014) Natalia Avaliani et al.   STEM CELLS

Chemical–genetic attenuation of focal neocortical seizures

(2014) Dennis Kätzel et al.   Nature Communications

Proposal for a “phase II” multicenter trial model for preclinical new antiepilepsy therapy development

(2013) Terence J. O'Brien et al.   EPILEPSIA

Identification of new epilepsy treatments: Issues in preclinical methodology

(2012) Aristea S. Galanopoulou et al.   EPILEPSIA

Drug refractoriness of epileptiform activity in organotypic hippocampal slice cultures depends on the mode of provocation

(2010) Abdul Wahab et al.   EPILEPSY RESEARCH

Optogenetic control of epileptiform activity

(2009) J. Tonnesen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Standard antiepileptic drugs fail to block epileptiform activity in rat organotypic hippocampal slice cultures

(2008) K Albus et al.   BRITISH JOURNAL OF PHARMACOLOGY