Reversal of Insulin Resistance in Overweight and Obese Subjects by trans-Resveratrol and Hesperetin Combination—Link to Dysglycemia, Blood Pressure, Dyslipidemia, and Low-Grade Inflammation

Dicarbonyl stress, protein glycation and the unfolded protein response

(2021) Naila Rabbani et al.   GLYCOCONJUGATE JOURNAL

Progress to Improve Oral Bioavailability and Beneficial Effects of Resveratrol

(2019) Adele Chimento et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Ameliorating Methylglyoxal-Induced Progenitor Cell Dysfunction for Tissue Repair in Diabetes.

(2019) Hainan Li et al.   DIABETES

Serum IL8 is not associated with cardiovascular events but with all-cause mortality

(2019) Ilais Moreno Velásquez et al.   BMC Cardiovascular Disorders

Activation of the unfolded protein response in high glucose treated endothelial cells is mediated by methylglyoxal

(2019) Zehra Irshad et al.   Scientific Reports

Urinary Metabolomic Markers of Protein Glycation, Oxidation, and Nitration in Early-Stage Decline in Metabolic, Vascular, and Renal Health

(2019) Jinit Masania et al.   Oxidative Medicine and Cellular Longevity

Lung Defense through Interleukin-8 Carries a Cost of Chronic Lung Remodeling and Impaired Function

(2018) Catherine J Reynolds et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Glyoxalase 1 Modulation in Obesity and Diabetes

(2018) Naila Rabbani et al.   ANTIOXIDANTS & REDOX SIGNALING

Inflammation and Monocyte Recruitment Due to Aging and Mechanical Stretch in Alveolar Epithelium are Inhibited by the Molecular Chaperone 4-Phenylbutyrate

(2018) M. S. Valentine et al.   Cellular and Molecular Bioengineering

Phosphorylation of TXNIP by AKT Mediates Acute Influx of Glucose in Response to Insulin

(2017) Althea N. Waldhart et al.   Cell Reports

Association between HOMA-IR and Lung Function in Korean Young Adults based on the Korea National Health and Nutrition Examination Survey

(2017) Young Bok Lee et al.   Scientific Reports

Methylglyoxal-induced dicarbonyl stress in aging and disease: first steps towards glyoxalase 1-based treatments

(2016) N. Rabbani et al.   CLINICAL SCIENCE

Monocyte chemoattractant protein-1 and the kidney

(2016) Hermann Haller et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Improved Glycemic Control and Vascular Function in Overweight and Obese Subjects by Glyoxalase 1 Inducer Formulation

(2016) Mingzhan Xue et al.   DIABETES

Novel plasma biomarkers associated with liver disease severity in adults with nonalcoholic fatty liver disease

(2016) Veeral Ajmera et al.   HEPATOLOGY

Macrophages and Iron Metabolism

(2016) Miguel P. Soares et al.   IMMUNITY

Translational Significance of Heme Oxygenase in Obesity and Metabolic Syndrome

(2016) Nader G. Abraham et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Frequency Modulated Translocational Oscillations of Nrf2 Mediate the Antioxidant Response Element Cytoprotective Transcriptional Response

(2015) Mingzhan Xue et al.   ANTIOXIDANTS & REDOX SIGNALING

Muscle-specific inflammation induced by MCP-1 overexpression does not affect whole-body insulin sensitivity in mice

(2015) Inkie J. A. Evers-van Gogh et al.   DIABETOLOGIA

Effect of resveratrol on glucose control and insulin sensitivity: a meta-analysis of 11 randomized controlled trials

(2014) Kai Liu et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Assay of methylglyoxal-derived protein and nucleotide AGEs

(2014) Naila Rabbani et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Measurement of glyoxalase activities

(2014) Makoto Arai et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The Receptor for Advanced Glycation End Products (RAGE) Specifically Recognizes Methylglyoxal-Derived AGEs

(2014) Jing Xue et al.   BIOCHEMISTRY

Measurement of methylglyoxal by stable isotopic dilution analysis LC-MS/MS with corroborative prediction in physiological samples

(2014) Naila Rabbani et al.   Nature Protocols

Arginine-directed glycation and decreased HDL plasma concentration and functionality

(2014) L Godfrey et al.   Nutrition & Diabetes

Pathophysiologic Approach to Therapy in Patients With Newly Diagnosed Type 2 Diabetes

(2013) R. A. DeFronzo et al.   DIABETES CARE

Txnip contributes to impaired glucose tolerance by upregulating the expression of genes involved in hepatic gluconeogenesis in mice

(2013) Seong Ho Jo et al.   DIABETOLOGIA

Tyrosine Sulfation of Chemokine Receptor CCR2 Enhances Interactions with Both Monomeric and Dimeric Forms of the Chemokine Monocyte Chemoattractant Protein-1 (MCP-1)

(2013) Joshua H. Y. Tan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thioredoxin-interacting protein regulates insulin transcription through microRNA-204

(2013) Guanlan Xu et al.   NATURE MEDICINE

Thioredoxin-Interacting Protein Mediates ER Stress-Induced β Cell Death through Initiation of the Inflammasome

(2012) Christine M. Oslowski et al.   Cell Metabolism

IRE1α Induces Thioredoxin-Interacting Protein to Activate the NLRP3 Inflammasome and Promote Programmed Cell Death under Irremediable ER Stress

(2012) Alana G. Lerner et al.   Cell Metabolism

High-Dose Resveratrol Supplementation in Obese Men: An Investigator-Initiated, Randomized, Placebo-Controlled Clinical Trial of Substrate Metabolism, Insulin Sensitivity, and Body Composition

(2012) M. M. Poulsen et al.   DIABETES

Activated Glucose-6-phosphate Dehydrogenase is Associated with Insulin Resistance by Upregulating Pentose and Pentosidine in Diet-induced Obesity of Rats

(2012) F. Wang et al.   HORMONE AND METABOLIC RESEARCH

Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation

(2011) Mingzhan Xue et al.   BIOCHEMICAL JOURNAL

Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans

(2011) Silvie Timmers et al.   Cell Metabolism

Glycation of LDL by Methylglyoxal Increases Arterial Atherogenicity: A Possible Contributor to Increased Risk of Cardiovascular Disease in Diabetes

(2011) N. Rabbani et al.   DIABETES

Citrus Polyphenol Hesperidin Stimulates Production of Nitric Oxide in Endothelial Cells while Improving Endothelial Function and Reducing Inflammatory Markers in Patients with Metabolic Syndrome

(2011) Stefano Rizza et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease

(2010) Gökhan S. Hotamisligil   CELL

Insulin Resistance Predicts Mortality in Nondiabetic Individuals in the U.S.

(2010) K. J. Ausk et al.   DIABETES CARE

Methylglyoxal Is a Predictor in Type 2 Diabetic Patients of Intima-Media Thickening and Elevation of Blood Pressure

(2010) Susumu Ogawa et al.   HYPERTENSION

Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis

(2010) Deepti Malhotra et al.   NUCLEIC ACIDS RESEARCH

Association Between Plasma Monocyte Chemoattractant Protein-1 Concentration and Cardiovascular Disease Mortality in Middle-Aged Diabetic and Nondiabetic Individuals

(2009) L. Piemonti et al.   DIABETES CARE

Mechanisms of TNF-α-induced insulin resistance

(2009) G. Hotamisligil   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Role of the Histone H3 Lysine 4 Methyltransferase, SET7/9, in the Regulation of NF-κB-dependent Inflammatory Genes

(2008) Yan Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Digital mRNA profiling

(2008) Paolo Fortina et al.   NATURE BIOTECHNOLOGY

COX-2 and CCR2 induced by CD40 ligand and MCP-1 are linked to VEGF production in endothelial cells

(2008) Seiji Futagami et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS