Journal
NUTRIENTS
Volume 13, Issue 8, Pages -Publisher
MDPI
DOI: 10.3390/nu13082564
Keywords
Astragalus; Shiitake; Hengshan Astragalus Shiitake; cancer immunology; medicinal food; bioactive
Categories
Funding
- Flinders University Innovation Partnership Seed Grant
- YLX International Pty Ltd. [ACN 630125272]
- Shanxi Yulongxiang Agricultural Development Co., Ltd.
- Flinders University
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The study reviewed the anticancer and immunomodulating properties of Astragalus root and Shiitake mushrooms, and assessed the potential of developing medicinal food by transferring Astragalus polysaccharides into edible Shiitake with increased therapeutic potential through a novel manufacturing process. Further research efforts are needed to validate the therapeutic potential of this new Hengshan Astragalus Shiitake medicinal food.
Astragalus root (Huang Qi) and Shiitake mushrooms (Lentinus edodes) are both considered medicinal foods and are frequently used in traditional Chinese medicine due to their anticancer and immunomodulating properties. Here, the scientific literatures describing evidence for the anticancer and immunogenic properties of Shiitake and Astragalus were reviewed. Based on our experimental data, the potential to develop medicinal food with combined bioactivities was assessed using Shiitake mushrooms grown over Astragalus beds in a proprietary manufacturing process, as a novel cancer prevention approach. Notably, our data suggest that this new manufacturing process can result in transfer and increased bioavailability of Astragalus polysaccharides with therapeutic potential into edible Shiitake. Further research efforts are required to validate the therapeutic potential of this new Hengshan Astragalus Shiitake medicinal food.
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