Article
Plant Sciences
Gang Nie, Zhongfu Yang, Jie He, Aiyu Liu, Jiayi Chen, Shuan Wang, Xia Wang, Guangyan Feng, Dandan Li, Yan Peng, Linkai Huang, Xinquan Zhang
Summary: The study identified 261 Miscanthus sinensis NAC genes and provided a detailed overview of the gene family, including gene structure, conserved motif compositions, chromosomal distribution, and gene duplications. Results showed variations in gene length, molecular weights, and theoretical isoelectric points of the NAC family, while gene structure and motifs were relatively conserved. Chromosomal mapping and evolutionary analysis indicated a correlation between gene duplication, especially segmental duplication, and the expansion of the M. sinensis NAC gene family.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Plant Sciences
Fangming Mei, Bin Chen, Fangfang Li, Yifang Zhang, Zhensheng Kang, Xiaojing Wang, Hude Mao
Summary: NAC transcription factors are crucial for plant responses to abiotic stresses. The study isolated three wheat TaSNAC4 homeologous genes and characterized the function of TaSNAC4-3A in plant drought tolerance. Overexpression of TaSNAC4-3A in Arabidopsis enhanced salt, osmotic and drought stress tolerance, reduced stomatal aperture size, and promoted root elongation and seed germination sensitivity to abscisic acid. Transcriptomic analysis showed upregulation of stress responsive genes in TaSNAC4-3A transgenic lines, emphasizing the important role of TaSNAC4-3A in plant drought tolerance.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Qi Wang, Cun Guo, Zhiyuan Li, Jinhao Sun, Zhichao Deng, Lichao Wen, Xiaoxu Li, Yongfeng Guo
Summary: The potato NAC transcription factor gene StNAC053 was significantly upregulated after salt, drought, and abscisic acid treatments, and its overexpression in Arabidopsis enhanced tolerance to salt and drought stress treatments by upregulating stress-related genes.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Plant Sciences
Dhawya Mergby, Moez Hanin, Mohammed Najib Saidi
Summary: The novel durum wheat NAC transcription factor gene TtNAC2A was found to play important roles in wheat development and stress responses by enhancing drought tolerance and hypersensitivity to ABA. It also activates a subset of stress-responsive genes, making it an attractive candidate for stress breeding in wheat crops.
ENVIRONMENTAL AND EXPERIMENTAL BOTANY
(2021)
Article
Plant Sciences
Jia-li Zhao, Qiong Wu, Hua-la Wu, An-hu Wang, Xiao-li Wang, Cheng-lei Li, Hai-xia Zhao, Qi Wu
Summary: Tartary buckwheat NAC TF gene FtNAC31 is upregulated under salt, drought, and ABA stress. Overexpression of FtNAC31 enhances salt and drought tolerance in transgenic Arabidopsis by regulating stress-associated genes and antioxidant enzyme activities.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2022)
Article
Plant Sciences
Yiren Su, Yang Liu, Shizhuo Xiao, Yuan Wang, Yitong Deng, Lukuan Zhao, Yao Wang, Donglan Zhao, Xibin Dai, Zhilin Zhou, Qinghe Cao
Summary: Adverse environmental stress is a major threat to food security, and improving plant stress resistance is crucial for agricultural productivity and environmental sustainability. The study focuses on the role of 12 IpNAC transcription factors in plant responses to abiotic stress, highlighting the importance of IpNAC5/8/10/12 in enhancing salt tolerance.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Agricultural Engineering
Jia Wang, Xuchu Duan, Yaozhou Wang, Jiajing Sheng
Summary: Transcriptome analysis of Miscanthus lutarioriparius under different Pb treatment times identified differentially expressed genes primarily related to phenylpropanoid biosynthesis, metabolism, secondary metabolite biosynthesis, photosynthesis, and metal ion transporters. These results lay the groundwork for future research on gene expression in plants under heavy metal stress and their potential applications in improving plant tolerance to toxic metals.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Plant Sciences
Meiheriguli Mijiti, Yucheng Wang, Liuqiang Wang, Xugela Habuding
Summary: ThNAC4, a NAC gene from Tamarix hispida, plays an important role in plant abiotic stress tolerance. Overexpression of ThNAC4 in Arabidopsis and Tamarix plants enhances salt and osmotic tolerance.
Article
Plant Sciences
Peng Feng, Xiaohuan Sun, Xiaodong Liu, Yuqiu Li, Qi Sun, Haoran Lu, Minglong Li, Xiaodong Ding, Yingshan Dong
Summary: The study found that the interaction between GsMYST1 and GsSnRK1 can regulate the expression of the COR15B gene through acetylation. Additionally, it was demonstrated that salt stress can activate GsSnRK1, which subsequently phosphorylates GsMYST1 to enhance its acetyltransferase activity, potentially promoting target gene expression through epigenetics.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Plant Sciences
Yue Li, Ziyao Hu, Yongmei Dong, Zongming Xie
Summary: The study characterized a member (GhGT26) of the cotton Trihelix family in Arabidopsis and found that it plays a role in response to high salt and ABA treatments. The GhGT26 protein positively regulates salt stress through an ABA-independent pathway, suggesting its involvement in stress tolerance in cotton.
Article
Biochemistry & Molecular Biology
Xinran Du, Mingxing Su, Yang Jiao, Suxiang Xu, Jieqiong Song, Hongfei Wang, Qiuli Li
Summary: In this study, a new NAC gene, SlNAC10, was cloned from the halophyte Suaeda liaotungensis K. The SlNAC10 gene was found to be highly expressed in the leaves of S. liaotungensis and induced by drought, salt, cold, and ABA. Transgenic Arabidopsis plants overexpressing SlNAC10 showed improved salt and drought tolerance, along with increased proline content and antioxidant enzyme activities. SlNAC10 was found to regulate the transcription of proline synthesis-related enzymes. This study suggests that SlNAC10 plays a role in enhancing salt and drought tolerance in plants by regulating proline synthesis.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Plant Sciences
Jing Ma, Li-yue Wang, Jia-xi Dai, Ying Wang, Duo Lin
Summary: CaNAC46 is an important transcription factor that regulates plant resistance to abiotic stresses such as drought and salinity by activating ROS-scavenging enzymes and enhancing root formation. The regulatory mechanisms controlling this NAC transcription factor appear to be conserved between Arabidopsis thaliana and pepper.
Article
Plant Sciences
Xueying Jin, Yufei Long, Shiqi Xiong, Zhen Yang, Wei Chen, Amangul Hawar, Xiaoyu Chi, Yaxin Chen, Huilian Luo, Jinliang Qi, Guihua Lu, Lingyan Dai, Yonghua Yang, Bo Sun
Summary: This study characterized a sorghum TF, SbNAC2, which is strongly induced by abiotic stresses and plays a crucial role in enhancing plant drought tolerance and inducing antioxidant enzyme activity. Furthermore, SbNAC2 directly activates the expression of stress responsive genes by binding to specific motifs, suggesting its potential as a regulator for improving crop yields under adverse environmental conditions.
ENVIRONMENTAL AND EXPERIMENTAL BOTANY
(2021)
Article
Plant Sciences
Mohamed Najib Saidi, Dhawya Mergby, Amel Souibgui, Ines Yacoubi
Summary: TtNTL3A is a membrane-bound NAC gene that plays important roles in wheat development, hormone signaling, and stress response. Overexpression of TtNTL3A results in early flowering and increased tolerance to salt, drought, and Fusarium graminearum infection.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2022)
Review
Biochemistry & Molecular Biology
Jianrong Guo, Baixue Sun, Huanrong He, Yifan Zhang, Huaying Tian, Baoshan Wang
Summary: bHLH proteins are a widespread transcription factor class in eukaryotes, regulating plant developmental and metabolic processes by binding to specific positions on their promoters. They play vital roles in plant responses to abiotic stresses, and future studies and applications of bHLH genes in plant breeding are promising.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Biotechnology & Applied Microbiology
Zhe Li, Zhengquan Gao, Ruihua Li, Yan Xu, Yingzhen Kong, Gongke Zhou, Chunxiao Meng, Ruibo Hu
Article
Plant Sciences
Yiping Wang, Yan Xu, Shengqiang Pei, Mingmin Lu, Yingzhen Kong, Gongke Zhou, Ruibo Hu
JOURNAL OF EXPERIMENTAL BOTANY
(2020)
Article
Agronomy
Congpeng Wang, Guo He, Jie Meng, Shumin Wang, Yingzhen Kong, Jianxiong Jiang, Ruibo Hu, Gongke Zhou
GLOBAL CHANGE BIOLOGY BIOENERGY
(2020)
Review
Agronomy
Congpeng Wang, Yingzhen Kong, Ruibo Hu, Gongke Zhou
Summary: Miscanthus, as an herbaceous perennial, has shown great potential in bioenergy production and ecological remediation due to its high yield and environmental adaptability. It has high biomass yield, calorific value, and cellulose content compared to other lignocellulosic bioenergy crops, making it a promising feedstock for second-generation biofuels. Miscanthus can also endure soil pollution and adverse environmental conditions, making it suitable for ecological remediation applications. However, further efforts are needed in genetic improvement, elite cultivar breeding, large-scale cultivation, and efficient biofuel conversion when utilizing Miscanthus as a bioenergy crop. Additionally, more work is required to fully unleash its phytoremediation potential.
GLOBAL CHANGE BIOLOGY BIOENERGY
(2021)
Article
Green & Sustainable Science & Technology
Ruibo Hu, Ke Chen, Weili Fang, Linzi Zheng, Jinying Xu
Summary: This research quantitatively assesses the differences in construction waste discharge between production modes that use and those that do not use prefabrication. The results show that prefabrication can effectively reduce most types of construction waste, with a waste generation rate 25.85% lower than non-prefabricated projects.
JOURNAL OF CLEANER PRODUCTION
(2022)
Article
Plant Sciences
Guohua Chai, Guang Qi, Dian Wang, Yamei Zhuang, Hua Xu, Zetao Bai, Ming-Yi Bai, Ruibo Hu, Zeng-Yu Wang, Gongke Zhou, Yingzhen Kong
Summary: This study reveals the negative regulatory mechanism of the Arabidopsis CCCH protein C3H15 in cell elongation through inhibiting brassinosteroid signaling. C3H15 functions downstream of the BRI1 receptor as a negative regulator in the BR pathway. It is phosphorylated by the kinase BIN2 and its dephosphorylation leads to its accumulation in the nucleus, where it regulates transcription of G-rich elements. C3H15 and the transcriptional regulators BZR1 and BES1 antagonize each other and share common BR-responsive target genes.
Article
Astronomy & Astrophysics
Trishool Namani, Reghan J. Ruf, Iskinder Arsano, Ruibo Hu, Chrys Wesdemiotis, Nita Sahai
Summary: This study investigates a novel class of chimeric amphiphiles called amino acid-fatty alcohol esters, which can self-assemble into stable primitive membranes under various geochemical conditions. Experimental results show that these esters can form vesicles in solutions with different pH values, and their stability can be expanded with the addition of co-surfactants. Molecular dynamics simulations support the experimental findings and suggest similar self-assembly behavior for other amino acid-fatty alcohol esters.
Article
Biochemistry & Molecular Biology
Xuhong Zhao, Yan Xu, Guo He, Kang He, Liang Xiao, Ruibo Hu, Shengjun Li
Summary: This study reports the identification of the GRAS gene family in the bioenergy crop Miscanthus. The role of MsGRAS60 as a negative regulator in salt and alkali stress response was characterized.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Plant Sciences
Xiangxiang Meng, Quanhui Wang, Ruili Hao, Xudong Li, Mu Li, Ruibo Hu, Hai Du, Zhubing Hu, Bin Yu, Shengjun Li
Summary: DNA damage response (DDR) is crucial for maintaining genome integrity in plants. This study reveals the role of MAC5A in DDR and its interaction with the 26S proteasome in Arabidopsis. MAC core subunits and the 26S proteasome are also involved in MMS-induced DDR. These findings contribute to a better understanding of the regulatory mechanisms of DDR in plants and its importance in growth and stress adaptation.
Article
Agronomy
Guo He, Xuhong Zhao, Yan Xu, Yu Wang, Zhihai Zhang, Liang Xiao, Matthew Hudson, Ruibo Hu, Shengjun Li
Summary: In this study, a highly efficient and stable virus-induced gene silencing system was established in Miscanthus, a bioenergy crop. The system was optimized by investigating various factors and resulted in the highest gene silencing efficiency. The established system can be applied to different Miscanthus varieties and facilitate functional genomic studies.
GLOBAL CHANGE BIOLOGY BIOENERGY
(2023)
Review
Biochemistry & Molecular Biology
Yan Xu, Ruibo Hu, Shengjun Li
Summary: The Arabidopsis seed coat mucilage is a polysaccharide-rich matrix synthesized by the seed coat epidermal cells. It serves as an ideal model system for plant cell wall research and has contributed to the understanding of the molecular mechanisms underlying mucilage synthesis and modification. This review summarizes the genes and regulators involved in seed coat cell differentiation, mucilage biosynthesis and modification, and secondary cell wall formation, with a focus on the transcriptional regulation of mucilage production.
Article
Biochemistry & Molecular Biology
Yan Xu, Yiping Wang, Jinge Du, Shengqiang Pei, Shuaiqiang Guo, Ruili Hao, Dian Wang, Gongke Zhou, Shengjun Li, Malcolm O'Neill, Ruibo Hu, Yingzhen Kong
Summary: DF1 is a key regulator of mucilage RG-I biosynthesis and interacts with GL2 to transcriptionally regulate the expression of MUM4 and GATL5. The expression of DF1 is directly regulated by TTG2 and DF1 also directly represses the expression of TTG2.
Article
Biochemistry & Molecular Biology
Anming Ding, Xianfeng Tang, Dahai Yang, Meng Wang, Angyan Ren, Zongchang Xu, Ruibo Hu, Gongke Zhou, Malcolm O'Neill, Yingzhen Kong
Summary: The study revealed that the demethylesterification of homogalacturonan in the mucilage of Arabidopsis thaliana seeds is regulated by the AP2/ERF transcription factor ERF4. ERF4 positively regulates the degree of demethylesterification by suppressing the expression of PME inhibitor genes and a protease gene. ERF4 and MYB52 antagonize each other's DNA-binding ability through physical interaction to regulate downstream gene expression in opposite directions.
Article
Plant Sciences
Yingzhen Kong, Shengqiang Pei, Yiping Wang, Yan Xu, Xiaoyu Wang, Gongke Zhou, Ruibo Hu
Summary: The study reveals that HDG2 is a positive regulator of cellulose biosynthesis in Arabidopsis seed coat mucilage, as it directly activates the expression of CESA5. This mechanism provides insights into the transcriptional regulation of genes involved in cellulose biosynthesis.
Article
Soil Science
Kang He, Guo He, Congpeng Wang, Hongpeng Zhang, Yan Xu, Shumin Wang, Yingzhen Kong, Gongke Zhou, Ruibo Hu
APPLIED SOIL ECOLOGY
(2020)
Article
Genetics & Heredity
Xiangge Meng, Chengping Li, Yu Hei, Xiang Zhou, Guoli Zhou
Summary: The study used IVT-SAPAS sequencing to analyze the dynamic changes of APA sites during adipogenesis in bovine subcutaneous preadipocytes and intramuscular preadipocytes. The results showed that APA plays an important role in adipocyte differentiation, and UTR-APA switching genes have different trends, with intramuscular preadipocytes tending to use shorter 3'UTR for differentiation. TRIB3, WWTR1, and INSIG1 play important roles in intramuscular preadipocyte differentiation.
Article
Genetics & Heredity
S. Alizadeh, S. Khamse, N. Tajeddin, H. R. Khorram Khorshid, A. Delbari, M. Ohadi
Summary: This study identifies a specific genotype at a CG-rich trinucleotide short tandem repeat (STR) locus that is associated with late-onset neurocognitive disorders such as Alzheimer's disease (AD).
Article
Genetics & Heredity
Shougang Liu, Zhe Zhuang, Fanghua Liu, Xiuqing Yuan, Zeqiao Zhang, Xiaoqian Liang, Xinhui Li, Yongfeng Chen
Summary: This study investigated the effect and mechanism of RPL9 and TIFA in scalp psoriasis, and identified RPL9 as a potential therapeutic target for scalp psoriasis.
Article
Genetics & Heredity
Shiting Wang, Jiaqi Chen, Zhichao Jin, Ying Xing, Ruiping Wang
Summary: This study suggests a causal association between hair color and skin cancers, with light hair colors (red, blonde, and light brown) being associated with an increased risk and dark brown hair being associated with a decreased risk.
Article
Genetics & Heredity
Joseph Hawadak, Loick Pradel Kojom Foko, Rodrigue Roman Dongang Nana, Karmveer Yadav, Veena Pande, Aparup Das, Vineeta Singh
Summary: This study investigates the genetic diversity and natural selection of the Pfama-1 gene in Plasmodium falciparum isolates from Cameroon. The study finds a considerable nucleotide and haplotype diversity, as well as specific mutations in Cameroonian isolates. Positive diversifying selection and the identification of selected codon sites suggest the potential implication of these genetic variations in host immune pressure and parasite-binding complex modulation. The findings provide valuable baseline data for malaria vaccine design.
Article
Genetics & Heredity
Emily Biernat, Mansi Verma, Chhabi K. Govind
Summary: RSC is an essential ATP-dependent chromatin remodeling complex in Saccharomyces cerevisiae. It regulates nucleosome-depleted regions (NDRs) by sliding flanking nucleosomes away from NDRs. Depletion of RSC leads to nucleosome encroachment in NDRs and transcription initiation defects. The study compared the effects of catalytic-dead Sth1 and rapid depletion of Sth1 on transcription. Rapid depletion of Sth1 reduces recruitment of TBP and Pol II, while the catalytic-dead mutant exhibits a severe reduction in TBP binding but accumulates Pol II in coding regions. The results suggest a role for RSC in transcription elongation and termination processes.
Article
Genetics & Heredity
Yunxiao Wei, Yuhan Song, Muhammad Aamir Khan, Chengzhen Liang, Zhigang Meng, Yuan Wang, Sandui Guo, Rui Zhang
Summary: This study analyzed the GhTPP protein family in upland cotton for the first time and identified the important role of GhTPPA_2 in regulating sugar metabolism, improving soluble sugar accumulation, and drought stress tolerance.
Article
Genetics & Heredity
Yannan Geng, Rui Shao, Tiantong Xu, Lilong Zhang
Summary: A novel risk model based on SCUBE3, TNNC1, SPON1, SEPT12 and ULBP1 genes was developed for predicting PMOP risk, with higher risk score indicating higher risk of suffering from PMOP. Significant differences in signaling pathway activities were observed between the high-risk score group and the low-risk score group.
Article
Genetics & Heredity
Randy P. Williams, Corina Lesseur, Haoxiang Cheng, Qian Li, Maya Deyssenroth, Christopher D. Molteno, Ernesta M. Meintjes, Sandra W. Jacobson, Joseph L. Jacobson, Helen Wainwright, Ke Hao, Jia Chen, R. Colin Carter
Summary: The study suggests that heavy alcohol exposure during pregnancy may impact the proportion of fetal placental villi macrophages and increase the expression of inflammatory genes. Further research is needed to explore these effects and evaluate the potential functional roles of placental inflammation in FASD.
Article
Genetics & Heredity
Lvjing Luo, Lishuang Sun, Shu Li, Huiting Liu, Zhengyu Chen, Shi Huang, Yinyin Mo, Genliang Li
Summary: This study analyzed the expression of Ptpn1 and miR-124-3p in testicular tissues of mice and investigated their regulatory relationship. The results showed that Ptpn1 expression was up-regulated in adult mouse testis compared to juvenile mouse testis, while miR-124-3p expression showed an opposite pattern. Further analysis suggested that the down-regulation of miR-124-3p may contribute to the high expression of Ptpn1 in adult mouse testis.
Article
Genetics & Heredity
Gairui Li, Dan Zhao, Xiaolin Peng, Yashuang Zhao
Summary: MiRNA-22 shows potential as a candidate for early diagnosis of colorectal cancer (CRC). The study found higher miR-22 expression levels in the CRC and CRA groups, suggesting its potential as a biomarker for CRC early screening.
Article
Genetics & Heredity
Zhongqiu Zhu, Qianting Yang, Xiaoying Tian, Da Man, Jian Wang, Junfang Zhang, Bingshe Han
Summary: This study constructed a ceRNA network mediated by lncRNAs in cold-acclimated zebrafish ZF4 cells and revealed that upregulation of MSTRG3207 promotes apoptosis by sponging dre-miR-736 during cold acclimation.
Article
Genetics & Heredity
Weitao Chen, Denggao Xiang, Shang Gao, Shuli Zhu, Zhi Wu, Yuefei Li, Jie Li
Summary: Dam construction has negatively impacted the genetic diversity and structure of fish populations. This case study on the endangered Hemibagrus guttatus found low genetic diversity, high levels of inbreeding, and decreasing population size in fragmented populations. Genetic structure and differentiation were also observed, indicating the influence of dams on these fish populations.
Article
Genetics & Heredity
Pooja Singh, Debleena Guin, Bijay Pattnaik, Ritushree Kukreti
Summary: Through systematic literature review and meta-analysis, it was found that idiopathic pulmonary fibrosis is significantly associated with 222 polymorphisms in 118 genes. Four polymorphisms - rs35705950/MUC5B, rs2736100/TERT, rs2076295/DSP, and rs111521887/TOLLIP, exhibited substantial epidemiological evidence supporting their association with IPF risk.
Article
Genetics & Heredity
Jianping Zhang, Zhijun Cai, Fanzhe Feng, Yufeng Peng, Yi Cui, Yongiqing Xu
Summary: This study found that exosomes secreted by young BMSCs can promote the healing of tendon-bone interface after rotator cuff tears. These exosomes can improve extracellular matrix remodeling, osteogenic differentiation, angiogenesis, and stemness of tendon-derived stem cells (TDSCs). The exosomes from young BMSCs have better effects compared to those from aged BMSCs.
