Article
Endocrinology & Metabolism
Caro Minschart, Astrid Lammertyn, Paul Van Crombrugge, Carolien Moyson, Johan Verhaeghe, Sofie Vandeginste, Hilde Verlaenen, Chris Vercammen, Toon Maes, Els Dufraimont, Nele Roggen, Christophe De Block, Yves Jacquemyn, Farah Mekahli, Katrien De Clippel, Annick Van Den Bruel, Anne Loccufier, Annouschka Laenen, Roland Devlieger, Chantal Mathieu, Katrien Benhalima
Summary: The level of gestational weight gain (GWG) during pregnancy is associated with adverse pregnancy outcomes in women with gestational diabetes (GDM) compared to women with normal glucose tolerance (NGT). Low GWG below recommended levels frequently occurs in GDM women without increased risk for adverse outcomes. Excessive GWG is associated with increased risk for neonatal hypoglycemia and worse metabolic profile postpartum in GDM women, and with higher rates of instrumental delivery and larger infants in NGT women.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Endocrinology & Metabolism
Xiaoqin Luo, Jiayi Gao, Zhangya He, Jing Ji, Wanyu Zhang, Pei Wu, Xiaoxiao Guo, Dan Cao, Zhangrui Xu, Chao Li, Yang Mi
Summary: This study investigated the appropriate range of gestational weight gain (GWG) in gestational diabetes mellitus (GDM) women and found that a stricter GWG range can prevent adverse pregnancy outcomes better than the recommendation of the US Institute of Medicine (IOM).
DIABETOLOGY & METABOLIC SYNDROME
(2022)
Article
Endocrinology & Metabolism
Marie Parfaite Uwimana Muhuza, Lixia Zhang, Qi Wu, Lu Qi, Danqing Chen, Zhaoxia Liang
Summary: This study investigated the association between HbA1c levels and adverse outcomes in women with gestational diabetes mellitus (GDM), considering maternal age, pre-pregnancy BMI, and gestational weight gain (GWG). The results showed that HbA1c was significantly associated with macrosomia, pregnancy-induced hypertension (PIH), preterm birth, and primary Cesarean section. The associations varied with maternal age, pre-pregnancy BMI, and GWG.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Medicine, General & Internal
Aiqi Yin, Fuying Tian, Xiaoxia Wu, Yixuan Chen, Kan Liu, Jianing Tong, Xiaonian Guan, Huafan Zhang, Linlin Wu, Jianmin Niu
Summary: This study evaluated the effect of weight gain in different trimesters on the risk of gestational diabetes mellitus (GDM). The results showed that insufficient weight gain in early pregnancy and excessive weight gain in middle pregnancy were associated with an increased risk of GDM. Strict control of weight gain in early pregnancy and sufficient nutrition in middle pregnancy are necessary.
CHINESE MEDICAL JOURNAL
(2022)
Article
Obstetrics & Gynecology
Jiang-Feng Ke, Sheng Liu, Ri-Le Ge, Li Ma, Mei-Fang Li
Summary: In women with gestational diabetes mellitus (GDM), maternal pre-pregnancy body mass index (ppBMI) and gestational weight gain (GWG) are associated with adverse pregnancy outcomes (APOs). The study found that obese mothers and excessive GWG increase the risk of APOs, while inadequate GWG increases the risk of preterm birth.
BMC PREGNANCY AND CHILDBIRTH
(2023)
Article
Endocrinology & Metabolism
Li-hua Lin, Juan Lin, Jian-ying Yan
Summary: In women with gestational diabetes mellitus, pre-pregnancy overweight or obesity, excessive gestational weight gain, and abnormal items of oral glucose tolerance test parameters independently contribute to adverse pregnancy outcomes, and the combined effect between these three factors appears to be multiplicative.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Medicine, General & Internal
Teresa A. Hillier, Kathryn L. Pedula, Keith K. Ogasawara, Kimberly K. Vesco, Caryn E. S. Oshiro, Suzanne L. Lubarsky, Jan Van Marter
Summary: In this study comparing one-step screening with two-step screening for gestational diabetes mellitus, the one-step approach resulted in more diagnoses of gestational diabetes mellitus but did not have a significant impact on the incidence of adverse perinatal and maternal outcomes.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Article
Medicine, General & Internal
Qiuhong Zhang, Chee Shin Lee, Lixia Zhang, Qi Wu, Yunyan Chen, Danqing Chen, Lu Qi, Zhaoxia Liang
Summary: Different factors, such as advanced age and high pre-pregnancy BMI, contribute to elevated HbA1c levels in pregnant women with GDM. Monitoring and controlling blood glucose levels have shown effectiveness in reducing adverse pregnancy outcomes, especially in cases of excessive GWG.
FRONTIERS IN MEDICINE
(2022)
Article
Obstetrics & Gynecology
Xiao-guang Yin, Peng Wang, Mei-ting Zhou, De-qin Li, Rui-xue Tao, Fang-biao Tao, Yang Wang, Peng Zhu
Summary: The timing of gestational diabetes mellitus (GDM) diagnosis and gestational weight gains (GWG) during pregnancy are associated with the growth trajectory of children from perinatal to early childhood. GDM diagnosed before 26 weeks increases the risk of fetal overgrowth and higher birth weight, as well as higher BMI peak within 48 months. Maternal early GDM diagnosis and excessive gestational weight gains have additive impacts on offspring overgrowth, with higher levels of hsCRP observed in the early EGWG group.
BMC PREGNANCY AND CHILDBIRTH
(2023)
Article
Endocrinology & Metabolism
Chee S. Lee, Shuqi Zhu, Qi Wu, Ying Hu, Yunyan Chen, Danqing Chen, Zhaoxia Liang
Summary: This study aimed to explore the independent and combined effects of maternal age, pre-pregnancy body mass index (BMI), and gestational weight gain (GWG) on pregnancy outcomes in gestational diabetes mellitus (GDM) patients. The results showed that advanced maternal age, high BMI, and excessive GWG increased the risk of adverse pregnancy outcomes in GDM patients.
Article
Obstetrics & Gynecology
Wei Zheng, Wenyu Huang, Cheng Liu, Qi Yan, Li Zhang, Zhihong Tian, Xianxian Yuan, Guanghui Li
Summary: Excessive gestational weight gain after an oral glucose tolerance test was found to be associated with an increased risk of adverse pregnancy outcomes in women with gestational diabetes mellitus (GDM). In contrast, restricting weight gain after the diagnosis of GDM in women with excessive weight gain in the first half of pregnancy may be beneficial in preventing various adverse outcomes.
BMC PREGNANCY AND CHILDBIRTH
(2021)
Article
Public, Environmental & Occupational Health
Feng Liang, Yun Lin, Ling Li, Chuanzi Yang, Xiaojun Li, Kuanrong Li
Summary: Appropriate gestational weight gain (GWG) is important for maternal and fetal health. This study validates and compares the Institute of Medicine (IOM) guidelines and the recently released guidelines for Chinese women with twin pregnancies regarding total GWG. The findings show that both guidelines are applicable to Chinese women with twin pregnancies.
Article
Nutrition & Dietetics
Thais Rangel Bousquet Carrilho, Jennifer A. Hutcheon, Kathleen M. Rasmussen, Michael E. Reichenheim, Dayana Rodrigues Farias, Nathalia Cristina Freitas-Costa, Gilberto Kac
Summary: This study aimed to determine the ranges of gestational weight gain (GWG) associated with the lowest risks of adverse maternal and infant outcomes using Brazilian GWG charts. The findings showed that GWG z-scores were associated with large-for-gestational-age (LGA) and small-for-gestational-age (SGA) births, indicating the importance of GWG range in affecting maternal and neonatal outcomes.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2023)
Article
Obstetrics & Gynecology
Huiling Xu, Jennifer A. Hutcheon, Xingrong Liu, Olof Stephansson, Sven Cnattingius, Elizabeth Arkema, Kari Johansson
Summary: This study investigated the association between gestational weight gain in early pregnancy and before diagnosis and the risk of gestational diabetes mellitus (GDM). The results showed that higher weight gain before diagnosis was associated with increased risk of GDM in all BMI groups, except for obese class III. Additionally, higher weight gain in early pregnancy was associated with increased risk of GDM in overweight women, while lower weight gain was associated with reduced risk of GDM in obese women. The findings suggest that obese women may benefit from lower weight gain, especially in early pregnancy.
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
(2022)
Article
Obstetrics & Gynecology
Melissa Amyx, Jennifer Zeitlin, Beatrice Blondel, Camille Le Ray
Summary: This study aimed to evaluate the association between gestational weight gain (GWG) and intrapartum obstetric interventions (oxytocin administration and cesarean section). The study found that excessive GWG was associated with oxytocin use and cesarean section, while inadequate GWG was also associated with oxytocin use. This suggests that maintaining a healthy GWG is important for normal labor progression.
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
(2023)