Longitudinal monitoring of tumor response to immune checkpoint inhibitors using noninvasive diffuse reflectance spectroscopy

Spectroscopic investigation of radiation-induced reoxygenation in radiation-resistant tumors

(2020) Sina Dadgar et al.   NEOPLASIA

Dual CTLA-4 and PD-L1 Blockade Inhibits Tumor Growth and Liver Metastasis in a Highly Aggressive Orthotopic Mouse Model of Colon Cancer

(2019) E Fiegle et al.   NEOPLASIA

Optical spectroscopic sensing of tumor hypoxia

(2018) Sina Dadgar et al.   JOURNAL OF BIOMEDICAL OPTICS

Quantitative diffuse reflectance spectroscopy of short-term changes in tumor oxygenation after radiation in a matched model of radiation resistance

(2018) Paola Monterroso Diaz et al.   Biomedical Optics Express

Nivolumab in patients with metastatic DNA mismatch repair-deficient or microsatellite instability-high colorectal cancer (CheckMate 142): an open-label, multicentre, phase 2 study

(2017) Michael J Overman et al.   LANCET ONCOLOGY

Oxygen and Perfusion Kinetics in Response to Fractionated Radiation Therapy in FaDu Head and Neck Cancer Xenografts Are Related to Treatment Outcome

(2016) Fangyao Hu et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Diffuse optical measurements of head and neck tumor hemodynamics for early prediction of chemoradiation therapy outcomes

(2016) Lixin Dong et al.   JOURNAL OF BIOMEDICAL OPTICS

Predictive biomarkers for checkpoint inhibitor-based immunotherapy

(2016) Geoffrey T Gibney et al.   LANCET ONCOLOGY

Preclinical Development of Ipilimumab and Nivolumab Combination Immunotherapy: Mouse Tumor Models, In Vitro Functional Studies, and Cynomolgus Macaque Toxicology

(2016) Mark J. Selby et al.   PLoS One

Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade

(2016) P.-L. Chen et al.   Cancer Discovery

Efficacy of PD-1 Blockade Is Potentiated by Metformin-Induced Reduction of Tumor Hypoxia

(2016) Nicole E. Scharping et al.   Cancer Immunology Research

Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression

(2015) Chih-Hao Chang et al.   CELL

PD-1 Blockade in Tumors with Mismatch-Repair Deficiency

(2015) Dung T. Le et al.   NEW ENGLAND JOURNAL OF MEDICINE

Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma

(2015) James Larkin et al.   NEW ENGLAND JOURNAL OF MEDICINE

Using Optical Spectroscopy to Longitudinally Monitor Physiological Changes within Solid Tumors

(2015) Karthik Vishwanath et al.   NEOPLASIA

Dual Blockade of PD-1 and CTLA-4 Combined with Tumor Vaccine Effectively Restores T-Cell Rejection Function in Tumors

(2013) J. Duraiswamy et al.   CANCER RESEARCH

Prognostic Significance of Tumor-Infiltrating Lymphocytes for Patients With Colorectal Cancer

(2012) Jae Hyuk Lee   ARCHIVES OF SURGERY

Performance of a lookup table-based approach for measuring tissue optical properties with diffuse optical spectroscopy

(2012) Brandon S. Nichols   JOURNAL OF BIOMEDICAL OPTICS

Noninvasive diffuse optical monitoring of head and neck tumor blood flow and oxygenation during radiation delivery

(2012) Lixin Dong et al.   Biomedical Optics Express

Experimental validation of the effects of microvasculature pigment packaging on in vivo diffuse reflectance spectroscopy

(2010) Narasimhan Rajaram et al.   LASERS IN SURGERY AND MEDICINE

Quantitative diffuse reflectance and fluorescence spectroscopy: tool to monitor tumor physiology in vivo

(2009) Gregory M. Palmer et al.   JOURNAL OF BIOMEDICAL OPTICS

Quantitative optical spectroscopy can identify long-term local tumor control in irradiated murine head and neck xenografts

(2009) Karthik Vishwanath et al.   JOURNAL OF BIOMEDICAL OPTICS

Lookup table–based inverse model for determining optical properties of turbid media

(2008) Narasimhan Rajaram et al.   JOURNAL OF BIOMEDICAL OPTICS