4.6 Article

Halloysite nanotubes and halloysite-based composites for biomedical applications

Journal

ARABIAN JOURNAL OF CHEMISTRY
Volume 14, Issue 9, Pages -

Publisher

ELSEVIER
DOI: 10.1016/j.arabjc.2021.103294

Keywords

Biomaterials; Drug release; Halloysite nanotubes; Nanomedicine; Tissue engineering; Wound healing

Funding

  1. Universiti Sains Malaysia under the RUI grant scheme [1001/PPSG/812158]

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Halloysite nanotubes (HNTs), as a natural material, have unique properties that make them ideal for biomedical applications, such as loading bioactive molecules and therapeutic agents. The review paper covers the characterizations, properties, and applications of HNTs-polymer nanocomposites in biomedical fields, providing an overview of their potential in personalized medicine and drug delivery methods for researchers developing novel biomaterials in biomedical engineering and health care.
Novel biomaterials for diagnostics and therapeutics of biomedical issues have been considered using biomedical science and health care. Halloysite nanotubes (HNTs) are naturally occurring aluminosilicate clay. Because of their unique hollow tubular structure, biodegradability, mechanical and surface properties, they have drawn the attention of researchers to a variety of biomedical applications. HNTs are inorganic natural aluminosilicates that are tubular-shaped and nanosized. These are well-known nanofillers and nanocontainers used to develop composites for various biomedical applications to load bioactive molecules and therapeutic agents. HNTs-polymer nanocomposites, their characterizations, properties, and applications in biomedical fields are all covered in this review paper. The current article provides an overview of HNTs and their applications in medical and biomedical settings, focusing on individualized HNTs and drug loading methods and biomedical applications, which may aid researchers in developing novel biomaterials for biomedical engineering and health care. Crown Copyright (C) 2021 Published by Elsevier B.V. on behalf of King Saud University.

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