Puma, noxa, p53, and p63 differentially mediate stress pathway induced apoptosis

Establishment and validation of an endoplasmic reticulum stress reporter to monitor zebrafish ATF6 activity in development and disease

(2019) Eric M. Clark et al.   Disease Models & Mechanisms

Deciphering p53 signaling in tumor suppression

(2018) Stephano S Mello et al.   CURRENT OPINION IN CELL BIOLOGY

Effect of PMA-induced protein kinase C activation on development and apoptosis in early zebrafish embryos

(2016) Jelena Hrubik et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

Observing Mitotic Division and Dynamics in a Live Zebrafish Embryo

(2016) Stefanie M. Percival et al.   Jove-Journal of Visualized Experiments

Induction of Excess Centrosomes in Neural Progenitor Cells during the Development of Radiation-Induced Microcephaly

(2016) Mikio Shimada et al.   PLoS One

Ataxia-telangiectasia — A historical review and a proposal for a new designation: ATM syndrome

(2015) Hélio A.G. Teive et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Tumor-specific signaling to p53 is mimicked by Mdm2 inactivation in zebrafish: insights from mdm2 and mdm4 mutant zebrafish

(2015) J S Chua et al.   ONCOGENE

Interdependence of Bad and Puma during Ionizing-Radiation-Induced Apoptosis

(2014) Cristhian Toruno et al.   PLoS One

High-Throughput Genome Editing and Phenotyping Facilitated by High Resolution Melting Curve Analysis

(2014) Holly R. Thomas et al.   PLoS One

The proapoptotic BH3-only proteins Bim and Puma are downstream of endoplasmic reticulum and mitochondrial oxidative stress in pancreatic islets in response to glucotoxicity

(2014) J A Wali et al.   Cell Death & Disease

p53/p63/p73 in the Epidermis in Health and Disease

(2014) V. A. Botchkarev et al.   Cold Spring Harbor Perspectives in Medicine

p53 Family and Cellular Stress Responses in Cancer

(2014) Johanna Pflaum et al.   Frontiers in Oncology

Efficient genome editing in zebrafish using a CRISPR-Cas system

(2013) Woong Y Hwang et al.   NATURE BIOTECHNOLOGY

p53 Efficiently Suppresses Tumor Development in the Complete Absence of Its Cell-Cycle Inhibitory and Proapoptotic Effectors p21, Puma, and Noxa

(2013) Liz J. Valente et al.   Cell Reports

The impact of the unfolded protein response on human disease

(2012) Shiyu Wang et al.   JOURNAL OF CELL BIOLOGY

7b, a novel amonafide analog, inhibited proliferation and phorbol 12-myristate 13-acetate/phytohemagglutinin-induced inflammatory responses of Jurkat T cells via p73-dependent pathway and decrease of nuclear factor-κB DNA-binding, respectively

(2012) Jin Shao et al.   LEUKEMIA & LYMPHOMA

Modeling Neurodegeneration in Zebrafish

(2011) Yanwei Xi et al.   Current Neurology and Neuroscience Reports

p63 Mediates an Apoptotic Response to Pharmacological and Disease-Related ER Stress in the Developing Epidermis

(2011) Ujwal J. Pyati et al.   DEVELOPMENTAL CELL

Physiological consequences of defects in ERCC1–XPF DNA repair endonuclease

(2011) Siobhán Q. Gregg et al.   DNA REPAIR

Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting

(2011) Tomas Cermak et al.   NUCLEIC ACIDS RESEARCH

Differential cytokine regulation by NF-κB and AP-1 in Jurkat T-cells

(2010) Hazem Khalaf et al.   BMC IMMUNOLOGY

New insights into p53 activation

(2010) Christopher L Brooks et al.   CELL RESEARCH

Genetic modeling of Li-Fraumeni syndrome in zebrafish

(2010) J. M. Parant et al.   Disease Models & Mechanisms

Regulation of tissue- and stimulus-specific cell fate decisions by p53 in vivo

(2010) James G Jackson et al.   JOURNAL OF PATHOLOGY

The DNA Damage Response: Making It Safe to Play with Knives

(2010) Alberto Ciccia et al.   MOLECULAR CELL

Mitochondria and cell death: outer membrane permeabilization and beyond

(2010) Stephen W. G. Tait et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Control of mitochondrial apoptosis by the Bcl-2 family

(2009) J. K. Brunelle et al.   JOURNAL OF CELL SCIENCE

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

Oligomerized pool engineering (OPEN): an 'open-source' protocol for making customized zinc-finger arrays

(2009) Morgan L Maeder et al.   Nature Protocols

One billion years of p53/p63/p73 evolution

(2009) V. A. Belyi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chk1 Suppresses a Caspase-2 Apoptotic Response to DNA Damage that Bypasses p53, Bcl-2, and Caspase-3

(2008) Samuel Sidi et al.   CELL

In several cell types tumour suppressor p53 induces apoptosis largely via Puma but Noxa can contribute

(2008) E M Michalak et al.   CELL DEATH AND DIFFERENTIATION

Transparent Adult Zebrafish as a Tool for In Vivo Transplantation Analysis

(2008) Richard Mark White et al.   Cell Stem Cell

The BCL-2 protein family: opposing activities that mediate cell death

(2007) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Apoptosis: controlled demolition at the cellular level

(2007) Rebecca C. Taylor et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY