GABAA-Receptor Agonists Limit Pneumonitis and Death in Murine Coronavirus-Infected Mice

GABAB-Receptor Agonist-Based Immunotherapy for Type 1 Diabetes in NOD Mice

(2021) Jide Tian et al.   Biomedicines

Immunology of COVID-19: current state of the science

(2020) Nicolas Vabret et al.   IMMUNITY

Lessons for COVID-19 Immunity from Other Coronavirus Infections

(2020) Alan Sariol et al.   IMMUNITY

Longitudinal analyses reveal immunological misfiring in severe COVID-19

(2020) Carolina Lucas et al.   NATURE

Platelet activation and platelet-monocyte aggregate formation trigger tissue factor expression in patients with severe COVID-19

(2020) Eugenio D. Hottz et al.   BLOOD

Effect of Propofol on the Production of Inflammatory Cytokines by Human Polarized Macrophages

(2019) Tsukasa Kochiyama et al.   MEDIATORS OF INFLAMMATION

Propofol reduces acute lung injury by up-regulating gamma-aminobutyric acid type a receptors

(2019) Tianfeng Huang et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Porcine deltacoronavirus (PDCoV) modulates calcium influx to favor viral replication

(2019) Dongcheng Bai et al.   VIROLOGY

Autocrine GABA signaling distinctively regulates phenotypic activation of mouse pulmonary macrophages

(2018) Luan Januzi et al.   CELLULAR IMMUNOLOGY

A Novel Orally Available Asthma Drug Candidate That Reduces Smooth Muscle Constriction and Inflammation by Targeting GABAA Receptors in the Lung

(2018) Gloria S. Forkuo et al.   MOLECULAR PHARMACEUTICS

Desflurane Attenuates Ventilator-Induced Lung Injury in Rats with Acute Respiratory Distress Syndrome

(2018) Xue Lin et al.   Biomed Research International

GABA Regulates Release of Inflammatory Cytokines From Peripheral Blood Mononuclear Cells and CD4 + T Cells and Is Immunosuppressive in Type 1 Diabetes

(2018) Amol K. Bhandage et al.   EBioMedicine

GABAergic signaling linked to autophagy enhances host protection against intracellular bacterial infections

(2018) Jin Kyung Kim et al.   Nature Communications

Homotaurine, a safe blood-brain barrier permeable GABAA-R-specific agonist, ameliorates disease in mouse models of multiple sclerosis

(2018) Jide Tian et al.   Scientific Reports

Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology

(2017) Rudragouda Channappanavar et al.   Seminars in Immunopathology

The anti-spasticity drug baclofen alleviates collagen-induced arthritis and regulates dendritic cells

(2015) Shichao Huang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Study of GABA in Healthy Volunteers: Pharmacokinetics and Pharmacodynamics

(2015) Junfeng Li et al.   Frontiers in Pharmacology

Baclofen, a GABABR Agonist, Ameliorates Immune-Complex Mediated Acute Lung Injury by Modulating Pro-Inflammatory Mediators

(2015) Shunying Jin et al.   PLoS One

Combined Therapy With GABA and Proinsulin/Alum Acts Synergistically to Restore Long-term Normoglycemia by Modulating T-Cell Autoimmunity and Promoting  -Cell Replication in Newly Diabetic NOD Mice

(2014) J. Tian et al.   DIABETES

Characteristics of endogenous γ-aminobutyric acid (GABA) in human platelets: functional studies of a novel collagen glycoprotein VI inhibitor

(2014) Kuan-Hung Lin et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Isoflurane Regulates Atypical Type-A γ-Aminobutyric Acid Receptors in Alveolar Type II Epithelial Cells

(2013) Yun-Yan Xiang et al.   ANESTHESIOLOGY

GABA Protects Human Islet Cells Against the Deleterious Effects of Immunosuppressive Drugs and Exerts Immunoinhibitory Effects Alone

(2013) Gérald J. Prud’homme et al.   TRANSPLANTATION

The Volatile Anesthetic Isoflurane Prevents Ventilator-Induced Lung Injury via Phosphoinositide 3-Kinase/Akt Signaling in Mice

(2012) Simone Faller et al.   ANESTHESIA AND ANALGESIA

Effects of anesthetic regimes on inflammatory responses in a rat model of acute lung injury

(2012) Spyridon Fortis et al.   INTENSIVE CARE MEDICINE

GABAergic Signaling Is Linked to a Hypermigratory Phenotype in Dendritic Cells Infected by Toxoplasma gondii

(2012) Jonas M. Fuks et al.   PLoS Pathogens

Tramiprosate in mild-to-moderate Alzheimer’s disease – a randomized, double-blind, placebo-controlled, multi-centre study (the Alphase Study)

(2011) Paul S. Aisen et al.   Archives of Medical Science

Oral GABA treatment downregulates inflammatory responses in a mouse model of rheumatoid arthritis

(2011) Jide Tian et al.   AUTOIMMUNITY

Anaesthetic Impairment of Immune Function Is Mediated via GABAA Receptors

(2011) Daniel W. Wheeler et al.   PLoS One

Oral Treatment with γ-Aminobutyric Acid Improves Glucose Tolerance and Insulin Sensitivity by Inhibiting Inflammation in High Fat Diet-Fed Mice

(2011) Jide Tian et al.   PLoS One

Anti-inflammatory effects of the GABAB receptor agonist baclofen in allergic contact dermatitis

(2010) Beatrice Duthey et al.   EXPERIMENTAL DERMATOLOGY

T Cell Epitope Specificity and Pathogenesis of Mouse Hepatitis Virus-1-Induced Disease in Susceptible and Resistant Hosts

(2010) A. Khanolkar et al.   JOURNAL OF IMMUNOLOGY

Increased GABAA channel subunits expression in CD8+ but not in CD4+ T cells in BB rats developing diabetes compared to their congenic littermates

(2010) Suresh Kumar Mendu et al.   MOLECULAR IMMUNOLOGY

Inhibitory role for GABA in autoimmune inflammation

(2010) R. Bhat et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anesthetic-induced Improvement of the Inflammatory Response to One-lung Ventilation

(2009) Elisena De Conno et al.   ANESTHESIOLOGY

Sevoflurane Ameliorates Gas Exchange and Attenuates Lung Damage in Experimental Lipopolysaccharide-induced Lung Injury

(2009) Stefanie Voigtsberger et al.   ANESTHESIOLOGY

Sevoflurane and isoflurane decrease TNF-α-induced gene expression in human monocytic THP-1 cells: Potential role of intracellular IκBα regulation

(2009) Boost   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Effect of tramiprosate in patients with mild-to-moderate alzheimer’s disease: Exploratory analyses of the MRI sub-group of the alphase study

(2009) S. Gauthier et al.   Journal of Nutrition Health & Aging

Toll-Like Receptor 4 Deficiency Increases Disease and Mortality after Mouse Hepatitis Virus Type 1 Infection of Susceptible C3H Mice

(2009) A. Khanolkar et al.   JOURNAL OF VIROLOGY

Protective and Pathologic Roles of the Immune Response to Mouse Hepatitis Virus Type 1: Implications for Severe Acute Respiratory Syndrome

(2009) A. Khanolkar et al.   JOURNAL OF VIROLOGY

GABAA receptors: Subtypes provide diversity of function and pharmacology

(2008) Richard W. Olsen et al.   NEUROPHARMACOLOGY