Journal
WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY
Volume 14, Issue 1, Pages -Publisher
WILEY
DOI: 10.1002/wnan.1754
Keywords
COVID-19; electrochemical detection; fluorescence resonance energy transfer; gold nanoparticle; in vitro diagnostics; lateral flow assay; microfluidic; point-of-care; surface plasmon resonance
Funding
- National Institutes of Health (NIH) [RF1AG052324, R01DK071801]
- Division of Materials Research [1808251]
- UW-Madison School of Pharmacy
- Wisconsin Alumni Research Foundation
- Milton J. Henrichs Chair Professorship
- National Science Foundation [DMR-1808251]
- Wisconsin Center for NanoBioSystems
- Division Of Materials Research
- Direct For Mathematical & Physical Scien [1808251] Funding Source: National Science Foundation
Ask authors/readers for more resources
In the midst of the COVID-19 pandemic, virus diagnostics have become crucial, with gold nanoparticle (AuNP) applications showing great potential in viral detection. Designing AuNP-based SARS-CoV-2 testing requires consideration of multiple factors, with the development of effective AuNP testing methods being critical for the future.
Viruses are infectious agents that pose significant threats to plants, animals, and humans. The current coronavirus disease 2019 pandemic, which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread globally and resulted in over 2 million deaths and immeasurable financial losses. Rapid and sensitive virus diagnostics become crucially important in controlling the spread of a pandemic before effective treatment and vaccines are available. Gold nanoparticle (AuNP)-based testing holds great potential for this urgent unmet biomedical need. In this review, we describe the most recent advances in AuNP-based viral detection applications. In addition, we discuss considerations for the design of AuNP-based SARS-CoV-2 testings. Finally, we highlight and propose important parameters to consider for the future development of effective AuNP-based testings that would be critical for not only this COVID-19 pandemic, but also potential future outbreaks. This article is categorized under: Diagnostic Tools > Biosensing Diagnostic Tools > In Vitro Nanoparticle-Based Sensing
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available