Targeting synaptic plasticity in schizophrenia: insights from genomic studies
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Title
Targeting synaptic plasticity in schizophrenia: insights from genomic studies
Authors
Keywords
schizophrenia, genomics, target identification, plasticity, translation
Journal
TRENDS IN MOLECULAR MEDICINE
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2021-08-18
DOI
10.1016/j.molmed.2021.07.014
References
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Note: Only part of the references are listed.- Induced pluripotent stem cells in psychiatry: an overview and critical perspective
- (2021) Alejandro De Los Angeles et al. BIOLOGICAL PSYCHIATRY
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- (2021) Niamh Mullins et al. NATURE GENETICS
- Update on the Molecular Genetics of Timothy Syndrome
- (2021) Rosemary Bauer et al. Frontiers in Pediatrics
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- (2021) Max Lam et al. NEUROPSYCHOPHARMACOLOGY
- Reversal of synaptic and behavioral deficits in a 16p11.2 duplication mouse model via restoration of the GABA synapse regulator Npas4
- (2020) Benjamin Rein et al. MOLECULAR PSYCHIATRY
- Integration analysis of methylation quantitative trait loci and GWAS identify three schizophrenia risk variants
- (2020) Hao Yu et al. NEUROPSYCHOPHARMACOLOGY
- Genetics of schizophrenia in the South African Xhosa
- (2020) S. Gulsuner et al. SCIENCE
- An integrative analysis of genome-wide association study and regulatory SNP annotation datasets identified candidate genes for bipolar disorder
- (2020) Xin Qi et al. International Journal of Bipolar Disorders
- Profiling gene expression in the human dentate gyrus granule cell layer reveals insights into schizophrenia and its genetic risk
- (2020) Andrew E. Jaffe et al. NATURE NEUROSCIENCE
- A computational tool (H-MAGMA) for improved prediction of brain-disorder risk genes by incorporating brain chromatin interaction profiles
- (2020) Nancy Y. A. Sey et al. NATURE NEUROSCIENCE
- Kalirin and Trio: RhoGEFs in synaptic transmission, plasticity, and complex brain disorders
- (2020) Jeremiah D. Paskus et al. TRENDS IN NEUROSCIENCES
- Neuronal defects in a human cellular model of 22q11.2 deletion syndrome
- (2020) Themasap A. Khan et al. NATURE MEDICINE
- TargetDB: A target information aggregation tool and tractability predictor
- (2020) Stephane De Cesco et al. PLoS One
- Single-Nucleus RNA-Seq Is Not Suitable for Detection of Microglial Activation Genes in Humans
- (2020) Nicola Thrupp et al. Cell Reports
- Open Targets Platform: supporting systematic drug–target identification and prioritisation
- (2020) David Ochoa et al. NUCLEIC ACIDS RESEARCH
- Genome-wide analysis reveals extensive genetic overlap between schizophrenia, bipolar disorder, and intelligence
- (2019) Olav B Smeland et al. MOLECULAR PSYCHIATRY
- Association of Hydroxylmethyl Glutaryl Coenzyme A Reductase Inhibitors, L-Type Calcium Channel Antagonists, and Biguanides With Rates of Psychiatric Hospitalization and Self-Harm in Individuals With Serious Mental Illness
- (2019) Joseph F. Hayes et al. JAMA Psychiatry
- The Oxford study of Calcium channel Antagonism, Cognition, Mood instability and Sleep (OxCaMS): study protocol for a randomised controlled, experimental medicine study
- (2019) Lauren Z. Atkinson et al. Trials
- Targeting the Small GTPase Superfamily through their Regulatory Proteins
- (2019) Janine L. Gray et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Genome-wide association study identifies 30 loci associated with bipolar disorder
- (2019) Eli A. Stahl et al. NATURE GENETICS
- A genetics-led approach defines the drug target landscape of 30 immune-related traits
- (2019) Hai Fang et al. NATURE GENETICS
- CommonMind Consortium provides transcriptomic and epigenomic data for Schizophrenia and Bipolar Disorder
- (2019) Gabriel E. Hoffman et al. Scientific Data
- Genome-wide Association Studies in Ancestrally Diverse Populations: Opportunities, Methods, Pitfalls, and Recommendations
- (2019) Roseann E. Peterson et al. CELL
- A Transcriptome-Wide Association Study implicates specific pre- and post-synaptic abnormalities in Schizophrenia
- (2019) Lynsey S Hall et al. HUMAN MOLECULAR GENETICS
- A major role for common genetic variation in anxiety disorders
- (2019) Kirstin L. Purves et al. MOLECULAR PSYCHIATRY
- Long-read sequencing reveals the complex splicing profile of the psychiatric risk gene CACNA1C in human brain
- (2019) Michael B. Clark et al. MOLECULAR PSYCHIATRY
- Neuronal impact of patient-specific aberrant NRXN1α splicing
- (2019) Erin Flaherty et al. NATURE GENETICS
- Attention-deficit hyperactivity disorder shares copy number variant risk with schizophrenia and autism spectrum disorder
- (2019) Olafur O. Gudmundsson et al. Translational Psychiatry
- Cellular calcium in bipolar disorder: systematic review and meta-analysis
- (2019) Paul J. Harrison et al. MOLECULAR PSYCHIATRY
- Landscape of Conditional eQTL in Dorsolateral Prefrontal Cortex and Co-localization with Schizophrenia GWAS
- (2018) Amanda Dobbyn et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection
- (2018) Antonio F. Pardiñas et al. NATURE GENETICS
- Developmental and genetic regulation of the human cortex transcriptome illuminate schizophrenia pathogenesis
- (2018) Andrew E. Jaffe et al. NATURE NEUROSCIENCE
- Dendritic structural plasticity and neuropsychiatric disease
- (2018) Marc P. Forrest et al. NATURE REVIEWS NEUROSCIENCE
- OUP accepted manuscript
- (2018) SCHIZOPHRENIA BULLETIN
- Comparative Analyses of Copy-Number Variation in Autism Spectrum Disorder and Schizophrenia Reveal Etiological Overlap and Biological Insights
- (2018) Itaru Kushima et al. Cell Reports
- Targeted Sequencing of 10,198 Samples Confirms Abnormalities in Neuronal Activity and Implicates Voltage-Gated Sodium Channels in Schizophrenia Pathogenesis
- (2018) Elliott Rees et al. BIOLOGICAL PSYCHIATRY
- Integrative functional genomic analysis of human brain development and neuropsychiatric risks
- (2018) Mingfeng Li et al. SCIENCE
- Comprehensive functional genomic resource and integrative model for the human brain
- (2018) Daifeng Wang et al. SCIENCE
- An xQTL map integrates the genetic architecture of the human brain's transcriptome and epigenome
- (2017) Bernard Ng et al. NATURE NEUROSCIENCE
- A Brief History of Long-Term Potentiation
- (2017) Roger A. Nicoll NEURON
- A quantitative review of the postmortem evidence for decreased cortical N-methyl-d-aspartate receptor expression levels in schizophrenia: How can we link molecular abnormalities to mismatch negativity deficits?
- (2016) Vibeke S. Catts et al. BIOLOGICAL PSYCHOLOGY
- Schizophrenia
- (2016) Michael J Owen et al. LANCET
- A systematic review of calcium channel antagonists in bipolar disorder and some considerations for their future development
- (2016) A Cipriani et al. MOLECULAR PSYCHIATRY
- Schizophrenia risk from complex variation of complement component 4
- (2016) Aswin Sekar et al. NATURE
- Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects
- (2016) Christian R Marshall et al. NATURE GENETICS
- BrainSeq: Neurogenomics to Drive Novel Target Discovery for Neuropsychiatric Disorders
- (2015) Christian R. Schubert et al. NEURON
- Brain disorders? Precisely
- (2015) T. R. Insel et al. SCIENCE
- De novo mutations in schizophrenia implicate synaptic networks
- (2014) Menachem Fromer et al. NATURE
- A polygenic burden of rare disruptive mutations in schizophrenia
- (2014) Shaun M. Purcell et al. NATURE
- L-Type CaV1.2 Calcium Channels: From In Vitro Findings to In Vivo Function
- (2014) Franz Hofmann et al. PHYSIOLOGICAL REVIEWS
- Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis
- (2013) LANCET
- Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
- (2013) S Hong Lee et al. NATURE GENETICS
- The Nature of Dopamine Dysfunction in Schizophrenia and What This Means for Treatment
- (2012) Oliver D. Howes et al. ARCHIVES OF GENERAL PSYCHIATRY
- De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia
- (2011) G Kirov et al. MOLECULAR PSYCHIATRY
- Neocortical excitation/inhibition balance in information processing and social dysfunction
- (2011) Ofer Yizhar et al. NATURE
- Dosage-dependent phenotypes in models of 16p11.2 lesions found in autism
- (2011) G. Horev et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Genome-Wide Association Study of Schizophrenia in a Japanese Population
- (2010) Masashi Ikeda et al. BIOLOGICAL PSYCHIATRY
- Abnormal neural oscillations and synchrony in schizophrenia
- (2010) Peter J. Uhlhaas et al. NATURE REVIEWS NEUROSCIENCE
- Resequencing and Association Analysis of the KALRN and EPHB1 Genes And Their Contribution to Schizophrenia Susceptibility
- (2010) Itaru Kushima et al. SCHIZOPHRENIA BULLETIN
- Kalirin loss results in cortical morphological alterations
- (2009) Zhong Xie et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Kalirin regulates cortical spine morphogenesis and disease-related behavioral phenotypes
- (2009) M. E. Cahill et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Kalirin-7 Is Required for Synaptic Structure and Function
- (2008) X.-M. Ma et al. JOURNAL OF NEUROSCIENCE
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