Review
Chemistry, Analytical
Ying Lan, Baixun He, Cherie S. Tan, Dong Ming
Summary: Aptamers are functional recognition ligands with high specificity and affinity, which can be utilized in biosensors for sensing biomolecules. Aptasensors, based on aptamers, are specific, sensitive, and cost-effective, and have shown advantages when combined with smartphone devices for point-of-care testing.
Review
Biotechnology & Applied Microbiology
Wei Chen, Qingteng Lai, Yanke Zhang, Zhengchun Liu
Summary: The infection of Staphylococcus aureus and the spread of drug-resistant bacteria pose a serious global public health threat. Developing a fast, simple, low-cost, specific and sensitive detection method for S. aureus is of great significance. Aptasensors, as alternatives to traditional detection methods, have shown promising applications in S. aureus detection.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Review
Biotechnology & Applied Microbiology
Sha Liu, Kaixuan Zhao, Meiyuan Huang, Meimei Zeng, Yan Deng, Song Li, Hui Chen, Wen Li, Zhu Chen
Summary: The global burden of foodborne disease is significant, with foodborne pathogens being the primary cause. The detection of foodborne pathogenic bacteria has rapidly developed in recent years, with methods such as immunoassay, molecular biology, microfluidic chip, metabolism, biosensor, and mass spectrometry being the main techniques. This study provides a comprehensive review of various rapid detection methods and discusses their limitations, advantages, and future development direction for accurate and rapid diagnosis and control of diseases in point-of-care testing (POCT) applications.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Chemistry, Analytical
Melika Haji Mohammadi, Sterre Mulder, Patricia Khashayar, Alireza Kalbasi, Mostafa Azimzadeh, Amir Reza Aref
Summary: Lab-on-a-chip (LOC) devices have revolutionized the field of metabolic detection by combining the advantages of biosensors and microfluidics. Saliva is now being recognized as a non-invasive alternative biofluid for diagnostics, leading to promising applications of LOCs in analyzing saliva for a wide range of medical situations and diseases. Advancements in utilizing LOCs for detecting various bacteria and viruses, cytokines, metabolites, kidney related diseases, prostate cancer, and oral diseases are being explored with the potential to aid in addressing current pandemics.
MICROCHEMICAL JOURNAL
(2021)
Review
Food Science & Technology
Tracy Ann Bruce-Tagoe, Shyju Bhaskar, Ruchita Rao Kavle, Jaison Jeevanandam, Caleb Acquah, Godfred Ohemeng-Boahen, Dominic Agyei, Michael K. Danquah
Summary: This article provides an overview of the limitations of conventional foodborne pathogen detection methods and the ability of aptamer-based biosensors to overcome these limitations. Aptamers can bind to target molecules with high specificity and have advantages of fast production, high stability, and tailored applications.
JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE
(2023)
Article
Chemistry, Multidisciplinary
Yingjia Liu, Dong Jiang, Siyuan Wang, Gaozhe Cai, Li Xue, Yanbin Li, Ming Liao, Jianhan Lin
Summary: A microfluidic biosensor based on immunomagnetic separation, enzyme catalysis, and electrochemical impedance analysis was developed for rapid and sensitive detection of S. typhimurium. The biosensor could quantitatively detect S. typhimurium in 1 hour and demonstrated good feasibility for practical applications.
CHINESE CHEMICAL LETTERS
(2022)
Review
Chemistry, Analytical
Shuaiwen Li, Zihui Chen, Feng Yang, Wanqing Yue
Summary: This article presents a review of recent progress in the integration of emerging 2D materials into LOC devices for the development of high-sensitivity biosensors, discussing the integration methods and sensing principles of both electrochemical and optical LOC biosensors. The challenges and prospects of using 2D materials in LOC biosensors are also examined.
MICROCHEMICAL JOURNAL
(2023)
Article
Environmental Sciences
V Karthik, B. Karuna, P. Senthil Kumar, A. Saravanan, R. Hemavathy
Summary: Recently, the decrease in water availability and quality due to industrialization and anthropogenic activities has led to heavy metals becoming significant pollutants in the water environment. Conventional monitoring techniques have drawbacks, and biosensors have emerged as reasonable devices for detecting environmental contaminants. This review summarizes the toxic effect, source, and occurrence of heavy metals, and discusses the use of lab on a chip with suitable recognition materials for heavy metal detection. The lab on a chip is a promising micro-electrical mechanical system device that enables fast, cost-effective, and highly sensitive analysis of heavy metals.
Article
Food Science & Technology
Li Xue, Fan Jiang, Xinge Xi, Yanbin Li, Jianhan Lin
Summary: This review focuses on the recent advances in microfluidic separators and biosensors for rapid and sensitive detection of foodborne pathogens. The key technologies for developing lab-on-chip separators and biosensors are illustrated, with particular emphasis on the strategy of lab-on-chip magnetic separation for continuous-flow isolation of pathogenic bacteria. The challenges and future perspectives for practical applications of lab-on-chip technologies in foods are also discussed.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2023)
Article
Chemistry, Analytical
Daphika S. Dkhar, Rohini Kumari, Shweta J. Malode, Nagaraj P. Shetti, Pranjal Chandra
Summary: Lab-on-a-chip (LOC) biosensors have attracted research interest for their potential in personal healthcare and disease diagnostics. This review discusses various fabrication methods and techniques for designing LOC sensing devices, as well as the types of transduction systems that play a crucial role in sensing. The detection of analytes, including small molecules, macromolecules, and cells, is comprehensively reviewed with illustrations and tables.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2023)
Article
Chemistry, Analytical
Xudong Shang, Jingyuan Yu, Chang Wang, Yan Du
Summary: In this study, an ultrasensitive pH-metric sandwich-type aptasensor was developed using CeO2 nanorods and MFP for detecting thrombin, showing eligible selectivity and detection limit of 1.17 nM.
Article
Chemistry, Analytical
Xin Li, Yishuang Li, Yuxin Wang, Pan Liang, Guosong Lai
Summary: A distance-regulated PEC sensor was developed for multiplex detection by using an i-Motif sequence as the signal transduction unit. By dynamically regulating the distance between the functional sequence and the electrode material, the photogenerated electrons on the sensor's surface were directionally transferred. The PEC sensor with dual signal output modes was successfully applied to detect two virus nucleic acid sequences.
ANALYTICAL CHEMISTRY
(2023)
Review
Chemistry, Analytical
Sheng Zhong, Linxi Chen, Xianhua Shi, Gangdong Chen, Duanping Sun, Luyong Zhang
Summary: Cardiovascular diseases (CVDs) are a serious threat to human life and health, and the rapid diagnosis and evaluation of CVDs have become crucial. Biosensors, especially electrochemical sensors based on aptamers, have shown great potential in detecting cardiac biomarkers. In this review, we introduce common cardiac biomarkers and summarize the detection strategies, structural types, detection range, and limit of detection (LOD) of electrochemical aptasensors for cardiac biomarkers such as cTnI, MYO, and CRP. The review also discusses the current obstacles and prospects for the development of electrochemical aptasensors.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Satish Kasturi, Sri Ramulu Torati, Yunji Eom, CheolGi Kim
Summary: This study developed a microfluidic channel and valves integrated electrochemical biosensor for detecting the neurotoxic beta-amyloid (1-42) biomarker. By forming antibody-antigen complexes on gold microelectrode integrated within fluidic chambers and controlling all measurements using pneumatic valves, the biosensor showed a linear response to various beta-amyloid antigen concentrations with enhanced detection limit and potential for efficient detection of other biomarkers.
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
(2021)
Article
Nanoscience & Nanotechnology
Kaizhen Wen, Yanyu Cai, Yuhong Guan
Summary: This research aimed to design a dual LAMP fluorescence detection system for HuNoVs, which can accurately detect the ORF1-ORF2 junction region, the most conserved area in HuNoVs genomes I and II. A rapid integrated detection platform for pediatric norovirus emergencies was built using a commercially available system based on magnetic bead-based nucleic acid extraction and LAMP fluorescence detection. The method showed cross-reactivity with four other viruses and demonstrated consistent results with conventional laboratory extracts for 28 clinical samples.
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY
(2023)
Article
Spectroscopy
Joost L. D. Nelis, J. Pablo Salvador, M. Pilar Marco, Christopher T. Elliott, Katrina Campbell
Summary: An immunoassay utilizing plasmonic coupling between immobilised gold nanorods and colloid gold nanospheres was developed for detecting the marine toxin domoic acid. By optimizing experimental conditions, uniform and high-quality nanorods were obtained, and plasmon coupling was used to detect the target substance.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Chemistry, Analytical
P. Nolan, S. Auer, A. Spehar, M. Oplatowska-Stachowiak, K. Campbell
Summary: To enhance global food security, there is a demand for improved monitoring of various toxins throughout the food supply chain. This study investigated the feasibility of using mass-based biosensors for multiplex mycotoxin detection, demonstrating the ability to simultaneously and semi-quantitatively detect three regulated toxins.
Review
Microbiology
Said Oulghazi, Sohaib Sarfraz, Maja A. Zaczek-Moczydlowska, Slimane Khayi, Abdelaziz Ed-Dra, Yassir Lekbach, Katrina Campbell, Lucy Novungayo Moleleki, Richard O'Hanlon, Denis Faure
Summary: The article introduces the characteristics, detection methods, genomics, distribution areas, taxonomical evolution, etc. of Pectobacterium brasiliense (Pbr), emphasizing the importance of its management.
Review
Chemistry, Analytical
Michael Dillon, Maja A. Zaczek-Moczydlowska, Christine Edwards, Andrew D. Turner, Peter I. Miller, Heather Moore, April McKinney, Linda Lawton, Katrina Campbell
Summary: In the past twenty years, the marine biotoxin analysis in routine regulatory monitoring has significantly advanced to high-end analytical techniques from the use of the mouse bioassay. Despite the availability of advanced methods and commercial standards, challenges such as high equipment costs, lengthy procedures, and qualified personnel remain for routine monitoring laboratories.
Article
Chemistry, Analytical
Joost L. D. Nelis, Davide Migliorelli, Lea Muehlebach, Silvia Generelli, Linda Stewart, Christopher T. Elliott, Katrina Campbell
Summary: A novel electrochemical immunosensor was developed for the detection of marine biotoxins DA and OA. The sensor showed excellent stability and sensitivity, achieving low LODs for both toxins in buffer and mussel extract.
Review
Food Science & Technology
Safiye Jafari, Julian Guercetti, Ariadni Geballa-Koukoula, Aristeidis S. Tsagkaris, Joost L. D. Nelis, M. -Pilar Marco, J. -Pablo Salvador, Arjen Gerssen, Jana Hajslova, Chris Elliott, Katrina Campbell, Davide Migliorelli, Loic Burr, Silvia Generelli, Michel W. F. Nielen, Shana J. Sturla
Summary: Standard methods for chemical food safety testing rely on mass spectrometry in official laboratories, but there is a demand for portable devices due to the need for sampling and expensive equipment. Recent technological advancements include smartphone-based, microfluidic chip-based, and paper-based devices, as well as the potential application of portable mass spectrometers in food testing.
Article
Chemistry, Analytical
M. S. Bacchu, M. R. Ali, S. Das, S. Akter, H. Sakamoto, S- Suye, M. M. Rahman, K. Campbell, M. Z. H. Khan
Summary: An electrochemical DNA biosensor was fabricated for the selective identification of S. Typhi in real samples. The biosensor showed a low limit of detection and the ability to be reused multiple times. The experimental results demonstrated the high feasibility and accuracy of using this biosensor for detecting S. Typhi in clinical and food samples.
ANALYTICA CHIMICA ACTA
(2022)
Article
Chemistry, Analytical
Prabir Kumar Kulabhusan, Katrina Campbell
Summary: Cyanobacteria are common in slow-moving and nutrient-rich water bodies due to changing climatic conditions, and the toxins produced by them, cyanotoxins, are increasing rapidly in freshwater, posing a challenge for detection. Various methods, including molecular and analytical techniques, as well as nanostructure-based sensors, are being used to detect cyanotoxins.
TRENDS IN ENVIRONMENTAL ANALYTICAL CHEMISTRY
(2021)
Review
Biotechnology & Applied Microbiology
Clare Mills, Katrina Campbell
Summary: There is an increasing demand for rapid and affordable in-field screening methods for low molecular weight (LMW) compound detection. This review examines the recent resurgence of using anti-idiotypes (Ab2s) and the potential role of phage display and nanobodies in improving LMW compound immunoassays.
TRENDS IN BIOTECHNOLOGY
(2022)
Article
Food Science & Technology
Edel Stone, Vincenzo Pennone, Kerri Reilly, Irene R. Grant, Katrina Campbell, Eric Altermann, Olivia McAuliffe
Summary: The study demonstrated that tailored polyhydroxyalkanoate bionanoparticles (PHA BNPs) displaying recombinant listeriophage enzymes have the ability to lysine and inhibit the growth of Listeria monocytogenes. In laboratory conditions, BNPs displaying only the amidase domain of the phage endolysin were more effective than BNPs displaying the full-length endolysin. However, under conditions that better represent those found in food processing environments, BNPs displaying the full-length endolysin showed a greater inhibitory effect.
Article
Chemistry, Analytical
Safiye Jafari, Loic Burr, Davide Migliorelli, Roger Galve, M. Pilar Marco, Katrina Campbell, Chris Elliott, Michele Suman, Shana J. Sturla, Silvia Generelli
Summary: Considering the complexities and speed of modern food chains, there is an increasing demand for point-of-need detection of food contaminants, particularly highly regulated chemicals and carcinogens such as aflatoxin B1. We report a user-friendly smartphone-based magneto-immunosensor on carbon black modified electrodes for point-of-need detection of aflatoxin B1 in cereals. The assay demonstrated a low limit of detection and high reproducibility, and its applicability was validated on the basis of EU guidelines. An open-source android application, AflaESense, was designed to provide a simple interface for data analysis.
ANALYTICA CHIMICA ACTA
(2022)
Article
Engineering, Environmental
Clare Mills, Michael J. Dillon, Prabir Kumar Kulabhusan, Diana Senovilla-Herrero, Katrina Campbell
Summary: A multiplex lateral flow immunoassay has been developed to detect marine biotoxins, with specific antibodies for each toxin group. The assay is capable of accurately detecting okadaic acid, saxitoxin, and domoic acid within EU regulatory limits. It offers a simple and portable solution for toxin screening in shellfish.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Water Resources
Andrew A. Meharg, Caroline Meharg, Manus Carey, Paul Williams, Zhengyu Shi, Katrina Campbell, Christopher Elliott, Ernest Marwa, Xiao Jiujin, Julia Gomes Farias, Fernando Teixeira Nicoloso, P. Mangala C. S. De Silva, Ying Lu, Andy J. Green, Eduardo Moreno-Jimenez, Angel Antonio Carbonell-Barrachina, Alessia Sommella, Massimo Pigna, Catherine Brabet, Didier Montet, Mahmud Hossain, M. Rafiqul Islam
Summary: Despite the lack of understanding about the variation and correlation of elements in staple grains, a comprehensive analysis of polished rice samples from 18 countries revealed major differences in elemental content based on geographic location, with some elements strongly associated while others showing weaker correlations.
EXPOSURE AND HEALTH
(2023)
Article
Food Science & Technology
Sim Ray Yue, Rajeev Shrivastava, Katrina Campbell, Michael John Walker
Summary: This study analyzed allergen food recalls issued by food regulatory bodies in the UK from 2016 to 2021. The analysis included food type, allergenic food group, reasons for recall, and food expiry status. The findings revealed an increasing trend in allergen-related recalls until 2019, with a peak of 118 recalls, followed by a decrease to 82 and 84 recalls in 2020 and 2021 respectively. Milk was the most recalled allergenic food group, accounting for 25.2% of recalls. The omission of priority allergens from the list of ingredients was the main reason for recalls, and the supermarket Lidl issued the most recalls with 37 recalls involving 62 products. Some recalls with expiry dates posed microbiological risks to consumers, especially in cereal & bakery products.
Review
Peripheral Vascular Disease
Saad Mahjub Atiku, Dennis Kasozi, Katrina Campbell
Summary: This study explored the prevalence of single nucleotide polymorphisms (SNPs) in ACE1 and ACE2 in different geographic locations and their association with COVID-19 prevalence. The DD genotype of ACE1 was found to be more prevalent in Europe and America, which had a higher impact of COVID-19 compared to Asia and Africa. The rs2285666 SNP of ACE2 varied in different locations. However, the association between ACE2 and COVID-19 remains inconclusive and further research is needed.
JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM
(2023)
Review
Food Science & Technology
Peiling Yan, Weiqing Lan, Jing Xie
Summary: Sodium alginate (SA) is an important marine polysaccharide that has extensive applications in food preservation and quality maintenance. Modification methods can be used to improve the properties of SA and make it compatible with other materials. Solvent-casting films and gels are common methods for using modified SA in food preservation.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2024)
Article
Food Science & Technology
Zhihui Yu, Yating Gao, Xinyi Jia, Shuai Cui, Li Ma, Dan Zheng, Xin Li, Long Li, Lixin Zhang, Yisheng Chen
Summary: This review provides a new perspective on the state-of-the-art research and application of high-intensity ultrasound (HIU) for modifying blue food proteins (BFPs). The effects of HIU treatment on the functional properties and structural composition of BFPs are comprehensively evaluated.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2024)
Review
Food Science & Technology
Honghong Zhang, Haoran Fan, Xueming Xu, Dan Xu
Summary: This review provides a comprehensive summary of changes in different components in frozen dough, including starch, gluten protein, lipid, and yeast, from a multiscale perspective. The methods of improving the production process of frozen dough, from main materials to end products, have been discussed. Key findings include the use of high gluten strength wheat flour and composite flour with high dietary fiber to improve the freezing resistance of gluten-starch matrix, as well as various methods to improve yeast freeze tolerance and the effects of different freezing rates.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2024)
Article
Food Science & Technology
Junhua Xie, Qiqiong Li, Shaoping Nie
Summary: This review provides an overview of bEVs' biology, evidence for their health benefits, and possible molecular pathways involved in their health-promoting effects, as well as perspectives for applications in foods and pharmaceuticals.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2024)
Article
Food Science & Technology
Jose Bueno-Mancebo, Adriana Artola, Raquel Barrena, Fernando Rivero-Pino
Summary: This review provides an overview of the characterization, production, and applications of sophorolipids (SLs) in the food industry. SLs exhibit bioactivity and environmental friendliness, making them suitable for various applications in food packaging, agriculture, and other areas. The importance of SLs in the context of the One Health approach is emphasized.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2024)
Letter
Food Science & Technology
Saurabh Singh
Summary: This paper is interesting and relevant to determining the moisture content of food products. However, it lacks the classification of oven drying methods, which are cost-effective and important for drying solids and semisolids.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2024)
Article
Food Science & Technology
Yong Cheng, Beijun Ang, Chaoyi Xue, Zhenyu Wang, Liduan Yin, Tong Wang, Qiuming Chen, Zhaojun Wang, Maomao Zeng, Wei Zhang, Jie Chen, Zhiyong He
Summary: Pollen fermentation can improve its nutrient profile, degrade allergenic compounds, enhance bioavailability, and promote gut health. Pollen can serve key roles in fermented food production and create opportunities for innovative product development. However, quality and safety considerations are important in pollen fermentation.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2024)
Review
Food Science & Technology
Fanghua Guo, Fereidoon Shahidi
Summary: This contribution summarizes the potential of anthocyanins as alternatives to antibiotics, focusing on their anti-oxidation, anti-inflammation, absorption, metabolism, antibacterial effects, and the possible mechanisms behind these effects. The use of encapsulation to improve stability and bioavailability of anthocyanins, as well as targeted delivery to the lower digestive tract, shows promise in replacing antibiotics. However, more in vivo studies are needed to further support these findings.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2024)
Article
Food Science & Technology
Muhammad Rehan Khan, Elena Torrieri, Florent Allais, Sami Fadlallah
Summary: This opinion paper explores the potential of integrating synthetic biology into microbial polymers to produce tailored biopolymers for food packaging applications. By leveraging synthetic biology tools and adopting safety assessment protocols established within the regulatory framework, this innovative approach has the potential to not only replace conventional methods but also address environmental concerns associated with traditional food packaging.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2024)
