Arsenic methylation – Lessons from three decades of research

Arsenic Metabolism in Mice Carrying a BORCS7/AS3MT Locus Humanized by Syntenic Replacement

(2020) Beverly H. Koller et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

The Structure of an As(III) S-Adenosylmethionine Methyltransferase with 3-Coordinately Bound As(III) Depicts the First Step in Catalysis

(2018) Charles Packianathan et al.   BIOCHEMISTRY

Ethnic, geographic and dietary differences in arsenic exposure in the multi-ethnic study of atherosclerosis (MESA)

(2018) Miranda R. Jones et al.   Journal of Exposure Science and Environmental Epidemiology

Polymorphisms of Arsenic (+3 Oxidation State) Methyltransferase and Arsenic Methylation Capacity Affect the Risk of Bladder Cancer

(2018) Ying-Chin Lin et al.   TOXICOLOGICAL SCIENCES

Ethnic, Geographic, and Genetic Differences in Arsenic Metabolism at Low Arsenic Exposure: A Preliminary Analysis in the Multi-Ethnic Study of Atherosclerosis (MESA)

(2018) Poojitha Balakrishnan et al.   International Journal of Environmental Research and Public Health

Estimating Inorganic Arsenic Exposure from U.S. Rice and Total Water Intakes

(2017) Madhavi Mantha et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Genetic susceptibility to breast cancer risk associated with inorganic arsenic exposure

(2017) Brenda Gamboa-Loira et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Conserved cysteine residues determine substrate specificity in a novel As(III) S-adenosylmethionine methyltransferase fromAspergillus fumigatus

(2017) Jian Chen et al.   MOLECULAR MICROBIOLOGY

AS3MT-mediated tolerance to arsenic evolved by multiple independent horizontal gene transfers from bacteria to eukaryotes

(2017) Michael Palmgren et al.   PLoS One

Recurrent horizontal transfer of arsenite methyltransferase genes facilitated adaptation of life to arsenic

(2017) Song-Can Chen et al.   Scientific Reports

Oxidation state specific analysis of arsenic species in tissues of wild-type and arsenic (+ 3 oxidation state) methyltransferase-knockout mice

(2016) Jenna M. Currier et al.   JOURNAL OF ENVIRONMENTAL SCIENCES

Comparative cytotoxicity of fourteen trivalent and pentavalent arsenic species determined using real-time cell sensing

(2016) Birget Moe et al.   JOURNAL OF ENVIRONMENTAL SCIENCES

Methylated and thiolated arsenic species for environmental and health research — A review on synthesis and characterization

(2016) William R. Cullen et al.   JOURNAL OF ENVIRONMENTAL SCIENCES

High exposure to inorganic arsenic by food: the need for risk reduction

(2015) Ursula Gundert-Remy et al.   ARCHIVES OF TOXICOLOGY

As(III) S-Adenosylmethionine Methyltransferases and Other Arsenic Binding Proteins

(2015) A. Abdul Ajees et al.   GEOMICROBIOLOGY JOURNAL

(A)Historical Science

(2015) Arturo Casadevall et al.   INFECTION AND IMMUNITY

Human Adaptation to Arsenic-Rich Environments

(2015) Carina M. Schlebusch et al.   MOLECULAR BIOLOGY AND EVOLUTION

Monomethylarsonous acid (MMA+3) Inhibits IL-7 Signaling in Mouse Pre-B Cells

(2015) Peace C. Ezeh et al.   TOXICOLOGICAL SCIENCES

A disulfide-bond cascade mechanism for arsenic(III)S-adenosylmethionine methyltransferase

(2015) Kavitha Marapakala et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Monomethylarsonous Acid (MMAIII) Has an Adverse Effect on the Innate Immune Response of Human Bronchial Epithelial Cells to Pseudomonas aeruginosa

(2015) Emily G. Notch et al.   PLoS One

Mutational analysis of residues in human arsenic (III) methyltransferase (hAS3MT) belonging to 5 Å around S-adenosylmethionine (SAM)

(2014) Xiangli Li et al.   BIOCHIMIE

Pathway of Human AS3MT Arsenic Methylation

(2014) Dharmendra S. Dheeman et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Chemical Mechanism of Arsenic Biomethylation

(2014) William R. Cullen   CHEMICAL RESEARCH IN TOXICOLOGY

Genetic variation in arsenic (+3 oxidation state) methyltransferase (AS3MT), arsenic metabolism and risk of basal cell carcinoma in a European population

(2014) Karin S. Engström et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

AS3MT, GSTO, and PNP polymorphisms: Impact on arsenic methylation and implications for disease susceptibility

(2014) Ray Antonelli et al.   ENVIRONMENTAL RESEARCH

Arsenic metabolism efficiency has a causal role in arsenic toxicity: Mendelian randomization and gene-environment interaction

(2014) B. L. Pierce et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Identification of the Third Binding Site of Arsenic in Human Arsenic (III) Methyltransferase

(2014) Xiangli Li et al.   PLoS One

Arsenic Binding to Proteins

(2013) Shengwen Shen et al.   CHEMICAL REVIEWS

Contribution of diet to aggregate arsenic exposures—An analysis across populations

(2013) Margaret Kurzius-Spencer et al.   Journal of Exposure Science and Environmental Epidemiology

Effect of dietary treatment with dimethylarsinous acid (DMAIII) on the urinary bladder epithelium of arsenic (+3 oxidation state) methyltransferase (As3mt) knockout and C57BL/6 wild type female mice

(2013) Puttappa R. Dodmane et al.   TOXICOLOGY

Structure of an As(III) S-Adenosylmethionine Methyltransferase: Insights into the Mechanism of Arsenic Biotransformation

(2012) A. Abdul Ajees et al.   BIOCHEMISTRY

Identification of Catalytic Residues in the As(III) S-Adenosylmethionine Methyltransferase

(2012) Kavitha Marapakala et al.   BIOCHEMISTRY

Rapid Equilibrium Kinetic Analysis of Arsenite Methylation Catalyzed by Recombinant Human Arsenic (+3 Oxidation State) Methyltransferase (hAS3MT)

(2012) Shuping Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Environmental exposure to arsenic, AS3MT polymorphism and prevalence of diabetes in Mexico

(2012) Zuzana Drobná et al.   Journal of Exposure Science and Environmental Epidemiology

Methylation of arsenic by recombinant human wild-type arsenic (+3 oxidation state) methyltransferase and its methionine 287 threonine (M287T) polymorph: Role of glutathione

(2012) Lan Ding et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Genome-Wide Association Study Identifies Chromosome 10q24.32 Variants Associated with Arsenic Metabolism and Toxicity Phenotypes in Bangladesh

(2012) Brandon L. Pierce et al.   PLoS Genetics

Analysis of arsenic metabolites in HepG2 and AS3MT-transfected cells

(2011) Takayuki Watanabe et al.   ARCHIVES OF TOXICOLOGY

Exposure to arsenic in drinking water is associated with increased prevalence of diabetes: a cross-sectional study in the Zimapán and Lagunera regions in Mexico

(2011) Luz M Del Razo et al.   Environmental Health

Direct analysis and stability of methylated trivalent arsenic metabolites in cells and tissues

(2011) Jenna M. Currier et al.   Metallomics

Effect of Sodium Arsenite Dose Administered in the Drinking Water on the Urinary Bladder Epithelium of Female Arsenic (+3 Oxidation State) Methyltransferase Knockout Mice

(2011) Masanao Yokohira et al.   TOXICOLOGICAL SCIENCES

Arsenic (+3 oxidation state) methyltransferase genotype affects steady-state distribution and clearance of arsenic in arsenate-treated mice

(2010) Michael F. Hughes et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Disruption of the Arsenic (+3 Oxidation State) Methyltransferase Gene in the Mouse Alters the Phenotype for Methylation of Arsenic and Affects Distribution and Retention of Orally Administered Arsenate

(2009) Zuzana Drobna et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Structure–function roles of four cysteine residues in the human arsenic (+3 oxidation state) methyltransferase (hAS3MT) by site-directed mutagenesis

(2009) Xiaoli Song et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Oxidation state specific generation of arsines from methylated arsenicals based on l-cysteine treatment in buffered media for speciation analysis by hydride generation-automated cryotrapping-gas chromatography-atomic absorption spectrometry with the multiatomizer

(2007) Tomáš Matoušek et al.   SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY