Article
Chemistry, Analytical
Tingting Liu, Ruiyong Zhou, Kechen Wu, Gangbing Zhu
Summary: A Ti(3)C(2)Tx MXene nanoribbons@gold (Ti(3)C(2)Tx MNR@Au) nanohybrid was prepared via a self-reduction process and its nanozyme activity was studied. The nanozyme activity of Ti(3)C(2)Tx MNR@Au was weak, but in the presence of Hg2+, it was significantly improved. Based on this, a highly sensitive homogeneous voltammetric (HVC) sensing strategy was proposed for detecting Hg2+.
ANALYTICA CHIMICA ACTA
(2023)
Article
Environmental Sciences
Rajib Biswas, Chinmay Barman, Ashamoni Neog, Sankar Biswas, Nirmal Mazumder
Summary: The proliferation of heavy metal ions in water is a serious problem that is escalating. Rapid detection of these ions in an aqueous solution is of immense significance. To address the growing concentration of heavy metal ions, a facile and cost-effective sensing scheme based on intensity modulation is proposed. The scheme, comprising of a smartphone, light source, and analyte, can detect heavy metal ions at ppb level with an average limit of detection (LOD) of approximately 0.5 ppb. Additionally, the scheme shows a recovery level of approximately 95% when assessing spiked tap water, indicating its applicability. Overall, this sensing scheme with minimal logistics has the potential to replace complex analysis procedures using bulky and sophisticated instruments.
Article
Biochemical Research Methods
Fei Hua, Fenglan Pan, Juanhua Yang, Yongkang Yan, Xueer Huang, Yali Yuan, Jinfang Nie, Hua Wang, Yun Zhang
Summary: This work presents two new colorimetric nanosensors for label-free and equipment-free quantitative detection of nanomolar concentrations of copper (II) (Cu2+) and mercury (II) (Hg2+) ions. The Cu2+ nanosensor utilizes the analyte to accelerate the formation of dispersed, uniform, spherical gold nanoparticles (AuNPs), resulting in a red solution. On the other hand, the Hg2+ nanosensor produces a blue solution consisting of aggregated AuNPs with various sizes and an enhanced Tyndall effect signal. By measuring the time of producing the red solution and the Tyndall effect intensity of the blue solution using a timer and a smartphone, respectively, the nanosensors achieve linear ranges and detection limits for Cu2+ and Hg2+.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Inorganic & Nuclear
Deepika Rani, Kuldeep Kumar Bhasin, Monika Singh
Summary: This study reported the first non-porous MOF material with an interpenetrating ladder structure for iodide sensing, exhibiting a unique double nucleophilic substitution reaction mechanism. The supramolecular structure of Co-bpe MOF was stabilized by strong hydrogen bonding. The material showed a significant color change in the presence of iodide, with a detection limit of 2.7 x 10(-7) M.
DALTON TRANSACTIONS
(2021)
Review
Engineering, Environmental
Zhuo Chen, Zhiyang Zhang, Ji Qi, Jinmao You, Jiping Ma, Lingxin Chen
Summary: This paper focuses on the chromogenic materials and sensing strategies for the colorimetric detection of heavy metal ions. The unique optical and chemical properties of each chromogenic material result in different colorimetric sensing mechanisms. The review categorizes the chromogenic materials into organic, inorganic, and other materials, and discusses their detailed sensing strategies, performance, and real sample applications. Current challenges and prospects related to the colorimetry of heavy metal ions are also explored.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Chemistry, Analytical
Lu Xiao, Yulan Zhao, Gang Chang, Huiling Yan, Rong Zou, Xiuhua Zhang, Shengfu Wang, Hanping He
Summary: In this study, a 3D high-porous conductive polymer hydrogel was developed for the effective capture of multiplex heavy metal ions. The hydrogel exhibited excellent electrical conductivity and a large surface area for increased ion immobilization. The sensor based on the hydrogel showed high sensitivities, low detection limit, and wide detection ranges for Cd2+, Pb2+, Hg2+, and Cu2+. Additionally, it demonstrated high accuracy in lake water testing.
ANALYTICA CHIMICA ACTA
(2023)
Review
Engineering, Environmental
Yongbiao Hua, Younes Ahmadi, Ki-Hyun Kim
Summary: Aluminum is a cost-effective and abundant metal used for the mass production of metal-organic frameworks (MOFs). Aluminum-based MOFs (Al-MOFs) have unique properties, such as excellent chemical and structural stability, making them highly researched for various applications. This review summarizes the recent progress in the synthesis/functionalization of Al-MOF materials, with a focus on their sensing applications for metal ion pollutants in liquids. The performances of Al-MOF-based sensing systems are evaluated and compared to other sensing systems in terms of key quality assurance criteria, such as the limit of detection (LOD). The challenges and future outlook for Al-MOF-based sensing systems are also discussed to promote their real-world applications.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Review
Chemistry, Analytical
Sayo O. Fakayode, Charuksha Walgama, Vivian E. Fernand Narcisse, Cidya Grant
Summary: Human exposure to heavy metal ions is linked to various health issues, and developing low-cost detection methods is a global priority.
Article
Chemistry, Multidisciplinary
Kangwoo Jin, Dohyun Moon, Ying-Pin Chen, Jinhee Park
Summary: In this study, a vapochromic sensor array based on metal-organic frameworks (MOFs) is developed to detect volatile organic compounds (VOCs) and humidity. The sensor changes color from red to green in response to VOCs, which is influenced by solvent pretreatment. The system enables qualitative and quantitative sensing of VOCs, generating unique color patterns corresponding to specific VOC types.
ADVANCED MATERIALS
(2023)
Article
Nanoscience & Nanotechnology
Li Li, Dexi CiRen, Zhengbo Chen
Summary: This report describes dual-channel colorimetric array sensors that can rapidly distinguish metal ions. By utilizing gold nanoparticles (AuNPs) and two colorimetric reactions, different metal ions exhibit distinct colorimetric response modes. Additionally, the DNA absorbed on the AuNP surface can alter the catalytic ability of the AuNPs to varying degrees, resulting in different visual response modes. Linear discriminant analysis (LDA) is employed to analyze and classify these signal modes, enabling clear discrimination of each analyte on a LDA plot.
ACS APPLIED NANO MATERIALS
(2022)
Review
Chemistry, Multidisciplinary
Pattan-Siddappa Ganesh, Sang-Youn Kim
Summary: This review investigates the latest research on MXenes in the fabrication of electrochemical sensors, with a particular focus on their application in detecting hazardous environmental pollutants. It also compares the properties of MXene with different nanomaterials and discusses the potential use of MXenes as electrode modifiers.
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
(2022)
Review
Chemistry, Inorganic & Nuclear
Sobhan Chatterjee, Xin-Yue Lou, Feng Liang, Ying-Wei Yang
Summary: Surface-functionalized gold and silver nanoparticles, known as AuNPs and AgNPs, have attracted widespread attention due to their exceptional properties and specific surface plasmon resonance. They have been extensively studied as colorimetric and fluorescent sensors, showing great potential in various applications.
COORDINATION CHEMISTRY REVIEWS
(2022)
Review
Materials Science, Multidisciplinary
Jiewei Zheng, Md Arifur Rahim, Jianbo Tang, Francois-Marie Allioux, Kourosh Kalantar-Zadeh
Summary: Contamination of heavy metal ions poses a growing threat to human health and ecosystems, requiring effective analytic sensing techniques. Electroanalytical techniques, particularly stripping voltammetry, play a crucial role in detecting heavy metal ions at trace levels. Post-transition metals exhibit unique properties that enhance the performance of stripping voltammetry in heavy metal ion sensing applications.
ADVANCED MATERIALS TECHNOLOGIES
(2022)
Article
Chemistry, Physical
Parinaz Abdollahiyan, Mohammad Hasanzadeh, Paria Pashazadeh-Panahi, Farzad Seidi
Summary: This study presents an innovative method for sensitive detection of Hg and Cu ions using cysteamine@gold nanoparticles and a novel microfluidic paper-based analytical device. The device offers selective, simple, fast, sensitive, quantitative, cost-effective, and eco-friendly detection of mercury and copper ions, with naked-eye detection capabilities and admirable stability.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Biophysics
Xianqiang Song, Xin Chen, Zhaoxiong Liang, Dan Xu, Yong Liang
Summary: A simple, rapid, and effective colorimetric sensor array for discrimination of metal ions is proposed in this study. By utilizing gold nanoparticles and two sensing channels, nine metal ions were successfully distinguished with a discrimination accuracy of 100%.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Article
Chemistry, Analytical
Qian Wu, Li Tian, Xiangyu Shan, Huiling Li, Chao Li, Juan Lu
Summary: A novel ECL sensor was developed by modifying Fe3CuO4-Ru(bpy)3+ and GO-CdS@ZnS on the electrode for the detection of permethrin. The sensor exhibited high sensitivity and a wide detection range.
Article
Chemistry, Analytical
Tingting Gong, Lei Liao, Bingying Jiang, Ruo Yuan, Yun Xiang
Summary: In this study, a fluorescent biosensing system for high sensitivity detection of MT was established using a new Ag+-stabilized DNA triplex probe (Ag+-SDTP) combined with catalytic hairpin assembly (CHA) and CRISPR/Cas12a signal enhancements. The sensing method is able to selectively detect MT from other non-specific molecules and can achieve low level detection of MT in diluted human serums, demonstrating its potential for monitoring disease-specific MT biomarker at trace levels.
Article
Chemistry, Analytical
Estrella Sanz Rodriguez, Kyra Wood, Paul R. Haddad, Brett Paull
Summary: This study presents a simple, rapid, and reliable method for determining boron in aqueous solutions using suppressed ion chromatography coupled to electrospray ionisation-triple quadrupole mass spectrometry. The method achieved a low limit of detection and demonstrated excellent analytical performance.
Article
Chemistry, Analytical
Aline Cournut, Paul Moustiez, Yannick Coffinier, Christine Enjalbal, Claudia Bich
Summary: Alzheimer's disease is a major cause of senile dementia and is characterized by the aggregation of neurofibrillary tangles and amyloid plaques in the brain. The A beta 1-42 peptide is considered the primary cause of neurotoxicity due to its insolubility and subsequent aggregation. A beta 1-42 and A beta 1-40 have been identified as relevant biomarkers for AD diagnosis, and SurfaceAssisted Laser Desorption/Ionization Mass Spectrometry (SALDI-MS) was used to monitor the A beta 1-42/A beta 1-40 ratio without prior sample treatment.
Article
Chemistry, Analytical
Dotse Selali Chormey, Buse Tugba Zaman, Tulay Borahan Kustanto, Sezin Erarpat Bodur, Suleyman Bodur, Elif Ozturk Er, Sezgin Bakirdere
Summary: This review provides an overview of the harmful effects of endocrine disrupting chemicals (EDCs) on human health and introduces the methods for analyzing EDCs. Recent research has focused on using green chemicals, such as deep eutectic solvents (DESs), for microextraction to ensure environmental safety.
Article
Chemistry, Analytical
Yan Zhang, Renfeng Xu, Jingjing Wu, Zhenghong Zhang, Yuhuang Wang, Hongqin Yang, Sheng Zhang
Summary: This study visualized the pore-like structures in prostate cancer cell membranes after treatment with the anticancer drug paclitaxel, demonstrating its mechanism of action related to oxidative damage.
Article
Chemistry, Analytical
Chihong Ma, Qin Zhou, Jinjin Shi, Hua Gao, Di Huang, Huimin Xue, Han Wang, Zhenzhong Zhang, Sen Yang, Junli Zhang, Kaixiang Zhang
Summary: We developed a CRISPR-empowered electrochemical biosensor, named PER-E-CRISPR, for amplification-free and sensitive detection of miR-21. The biosensor combines the advantages of CRISPR/Cas13a and primer exchange reaction (PER) for target amplification. Under optimized conditions, the PER-E-CRISPR assay exhibits a linear range from 10-13 to 10-7 M and a limit of detection of 30.2 fM. The biosensor shows excellent performance in actual plasma, indicating promising prospects for miRNA detection in molecular diagnosis.
Article
Chemistry, Analytical
Gang Liang, Jie Zhao, Yufei Gao, Tao Xie, Jianhui Zhen, Ligang Pan, Wenwen Gong
Summary: Molecular docking (MD) analysis is widely used for studying the interaction between aptamers and small molecules. This study established steady-state aptamers of tertiary structures (SATS) using specific aptamers of tetracycline antibiotics as docking models. Molecular docking results revealed multiple binding sites in the SATS of aptamers, with significant variations in binding free energy (BFE) and docking score (DS). The study also proposed a method for MD analysis based on SATS, providing insights into binding mode and predicting binding sites.
Article
Chemistry, Analytical
Yixuan Xu, Changchang Teng, Huiping Dang, Dalong Yin, Lifeng Yan
Summary: Stable organic radical molecules with high NIR fluorescence quantum efficiency have been synthesized and encapsulated into nanoparticles, which show great potential for both photodynamic therapy (PDT) and photothermal therapy (PTT) of tumors.
Article
Chemistry, Analytical
Yu Su, Dandan Yang, Yanjie Wang, Jie Ding, Lan Ding, Daqian Song
Summary: In this study, a highly selective molecularly imprinted polymer Cu-MIPs@CS was designed and synthesized for bisphenol A (BPA). Cu-MIPs@CS showed significantly enhanced imprinting factor and selective factor towards BPA compared to MIPs@CS. It also exhibited superior discrimination ability between BPA and its structural analogue. Additionally, Cu-MIPs@CS were successfully applied as a solid phase extraction adsorbent for the determination of BPA in drinking water samples.
Article
Chemistry, Analytical
Yi Qiao, Qiongdan Zhang, Yukun He, Tianguang Cheng, Jing Tu
Summary: Single cell heterogeneity plays an important role in many biological phenomena, and distinguishing cells with specific mutations is beneficial for clinical diagnosis and drug screening. This study introduces a gel plate platform that can distinguish cell types based on their phenotypes, with low equipment requirement. The gel platform has potential in point-of-care circumstances and single-cell stimulation responses that prioritize efficiency and simplicity.
Article
Chemistry, Analytical
Chengke Wang, Shuyang Sun, Ping Wang, Huawei Zhao, Wenling Li
Summary: The food safety of aquatic products is a global concern. Nanotechnology-based analyses have advantages in the detection of bacteria, metal ions, and small molecule contaminants. This review summarizes the recent advances in biosensing strategies for aquatic products and highlights the application of nanomaterials, lateral flow-based biosensors, surface-enhanced Raman scattering, microfluidic chips, and molecular imprinting technologies.
Article
Chemistry, Analytical
Liping Zhu, Zeng Tang, Xuemei Zhang, Li Zhu, Tian Meng, Linying Yu, Ting Xiao, Shasha Lu, Xiaoli Xiong, Xiurong Yang
Summary: A sensitive off-on electrochemiluminescence DNA sensor was developed using Exo III-assisted cascade amplification system. The sensor achieved high selectivity and ultra-high sensitivity in detecting target DNA by utilizing ECL and SPR effects. This study provides a new perspective for designing highly sensitive and programmable ECL biosensors.
Article
Chemistry, Analytical
Tong Li, Mengxu Sun, Suping Xia, Ting Huang, Rong-Tian Li, Chunrong Li, Zong Dai, Jin-Xiang Chen, Jun Chen, Nuan Jia
Summary: Here, we developed a binary system based on DNA tetrahedron and fluorogenic RNA aptamers for highly specific and label-free mRNA imaging in living cells. This system achieved high specificity label-free detection of nucleic acids with a detection limit of 1.34 nM. The method has potential applications in early disease diagnosis and new drug development.
Article
Chemistry, Analytical
Yao Zhao, Shu Zhang, Wang Yao, Yuxuan Zhu, Jing Qian, Juan Yang, Nianjun Yang
Summary: A new hierarchical nanostructured composite with high conductivity and catalytic activity is synthesized. The sensor exhibits significant catalytic effect and high sensitivity for monitoring the environmental endocrine disruptor bisphenol A (BPA).