SARS-CoV-2 vs. human gametes, embryos and cryopreservation

Human SARS CoV ‐2 spike protein mutations

(2021) Lalitha Guruprasad   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

SARS-CoV-2 persistence at subzero temperatures

(2021) Catello Scarica et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Maternal, neonatal and placental characteristics of SARS-CoV-2 positive mothers

(2021) Peilin Zhang et al.   Journal of Maternal-Fetal & Neonatal Medicine

COVID-19 and male reproductive function: a prospective, longitudinal cohort study

(2021) Behzad Hajizadeh Maleki et al.   REPRODUCTION

Embryotoxic impact of Zika virus in a rhesus macaque in vitro implantation model†

(2020) Lindsey N Block et al.   BIOLOGY OF REPRODUCTION

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

(2020) Daniel Wrapp et al.   SCIENCE

Susceptibility of Chicken Embryos, Sheep, Cattle, Pigs, and Chickens to Zika Virus Infection

(2020) Aruna Ambagala et al.   Frontiers in Veterinary Science

Is there an impact of the COVID-19 pandemic on male fertility? The ACE2 connection

(2020) Johnny S. Younis et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Tmprss12 is required for sperm motility and uterotubal junction migration in mice†

(2020) Tamara Larasati et al.   BIOLOGY OF REPRODUCTION

Absence of 2019 novel coronavirus in semen and testes of COVID-19 patients†

(2020) Ci Song et al.   BIOLOGY OF REPRODUCTION

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

COVID-19 Transmission Within a Family Cluster by Presymptomatic Carriers in China

(2020) Guoqing Qian et al.   CLINICAL INFECTIOUS DISEASES

SARS ‐CoV‐2 receptor ACE 2 and TMPRSS 2 are primarily expressed in bronchial transient secretory cells

(2020) Soeren Lukassen et al.   EMBO JOURNAL

Coronavirus disease (COVID-19) and fertility: viral host entry protein expression in male and female reproductive tissues

(2020) Kate E. Stanley et al.   FERTILITY AND STERILITY

COVID-19: lessons from the Italian reproductive medical experience

(2020) Antonio La Marca et al.   FERTILITY AND STERILITY

Assessment of SARS-CoV-2 in human semen - a cohort study

(2020) Holtmann Nora et al.   FERTILITY AND STERILITY

Second-Trimester Miscarriage in a Pregnant Woman With SARS-CoV-2 Infection

(2020) David Baud et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

A recommendation for IVF lab practice in light of the current COVID-19 pandemic

(2020) Amir Arav   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

COVID-19 and assisted reproductive technology services: repercussions for patients and proposal for individualized clinical management

(2020) Carlo Alviggi et al.   Reproductive Biology and Endocrinology

Potential risks of SARS-CoV-2 infection on reproductive health

(2020) Rong Li et al.   REPRODUCTIVE BIOMEDICINE ONLINE

COVID-19 and fertility: a virtual reality

(2020) George Anifandis et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Managing the IVF laboratory during a pandemic: International perspectives from laboratory managers

(2020) Cristina Hickman et al.   REPRODUCTIVE BIOMEDICINE ONLINE

A picture of the covid-19 impact on IVIRMA fertility treatment clinics in Spain and Italy

(2020) Antonio Requena et al.   REPRODUCTIVE BIOMEDICINE ONLINE

SARS‐CoV‐2 Presence in seminal fluid: myth or reality

(2020) Donatella Paoli et al.   Andrology

It is currently unknown whether SARS‐CoV‐2 is viable in semen or whether COVID‐19 damages sperm

(2020) Melissa J. Perry et al.   Andrology

SARS-CoV-2 infection, male fertility and sperm cryopreservation: a position statement of the Italian Society of Andrology and Sexual Medicine (SIAMS) (Società Italiana di Andrologia e Medicina della Sessualità)

(2020) G. Corona et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

COVID-19 and the endocrine system: exploring the unexplored

(2020) R. Pal et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

scRNA-seq Profiling of Human Testes Reveals the Presence of the ACE2 Receptor, A Target for SARS-CoV-2 Infection in Spermatogonia, Leydig and Sertoli Cells

(2020) Zhengpin Wang et al.   Cells

EZH2-mediated H3K27me3 inhibits ACE2 expression

(2020) Yuanyuan Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

SARS-CoV-2 infection risk assessment in the endometrium: viral infection-related gene expression across the menstrual cycle

(2020) Ismael Henarejos-Castillo et al.   FERTILITY AND STERILITY

Coronavirus disease 2019 and men’s reproductive health

(2020) Michael L. Eisenberg   FERTILITY AND STERILITY

No evidence of severe acute respiratory syndrome–coronavirus 2 in semen of males recovering from coronavirus disease 2019

(2020) Feng Pan et al.   FERTILITY AND STERILITY

Potential effects of SARS‐CoV ‐2 infection during pregnancy on fetuses and newborns are worthy of attention

(2020) Dan Dang et al.   JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH

Viral dynamics in mild and severe cases of COVID-19

(2020) Yang Liu et al.   LANCET INFECTIOUS DISEASES

Assessment and management of the risk of SARS-CoV-2 infection in an IVF laboratory

(2020) Roberta Maggiulli et al.   REPRODUCTIVE BIOMEDICINE ONLINE

COVID-19: should we continue to cryopreserve sperm during the pandemic?

(2020) Michael Bright Yakass et al.   REPRODUCTIVE BIOMEDICINE ONLINE

After corona: there is life after the pandemic

(2020) Jan Tesarik   REPRODUCTIVE BIOMEDICINE ONLINE

SARS-CoV-2 and the testis: similarity with other viruses and routes of infection

(2020) Walter D. Cardona Maya et al.   REPRODUCTIVE BIOMEDICINE ONLINE

SARS‐CoV‐2 in the semen: Where does it come from?

(2020) Claudia Massarotti et al.   Andrology

Human sperm vitrification: A scientific report

(2020) Mabel Schulz et al.   Andrology

SARS-CoV-2 host receptors ACE2 and CD147 (BSG) are present on human oocytes and blastocysts

(2020) Wafaa Essahib et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Caution in the use of standard sperm-washing procedures for assisted reproduction in HPV-infected patients

(2020) Andrea Garolla et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Fertility preservation during the COVID-19 pandemic: mitigating the viral contamination risk to reproductive cells in cryostorage

(2020) Satish K. Adiga et al.   REPRODUCTIVE BIOMEDICINE ONLINE

COVID-19 unlikely to cause birth defects, but doctors await fall births

(2020) Meredith Wadman   SCIENCE

SARS-CoV-2 and the reproductive system: assessment of risk and considerations for infection control in reproductive departments

(2020) Guanjian Li et al.   Systems Biology in Reproductive Medicine

Gender susceptibility to COVID-19: a review of the putative role of sex hormones and X chromosome

(2020) C. Foresta et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

SARS-CoV-2 Entry Factors: ACE2 and TMPRSS2 Are Expressed in Peri-Implantation Embryos and the Maternal–Fetal Interface

(2020) Wei Chen et al.   Engineering

Investigation of SARS‐CoV‐2 in semen samples and the effects of COVID‐19 on male sexual health by using semen analysis and serum male hormone profile: A cross‐sectional, pilot study

(2020) Mustafa Zafer Temiz et al.   ANDROLOGIA

Susceptibility of turkeys, chickens and chicken embryos to SARS‐CoV‐2

(2020) Yohannes Berhane et al.   Transboundary and Emerging Diseases

D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction

(2020) Sophie M.-C. Gobeil et al.   Cell Reports

No detection of SARS‐CoV‐2 from urine, expressed prostatic secretions, and semen in 74 recovered COVID‐19 male patients: A perspective and urogenital evaluation

(2020) Yajun Ruan et al.   Andrology

TMPRSS2 contributes to virus spread and immunopathology in the airways of murine models after coronavirus infection

(2019) Naoko Iwata-Yoshikawa et al.   JOURNAL OF VIROLOGY

Persistence and clinical relevance of Zika virus in the male genital tract

(2019) Fábio A. Kurscheidt et al.   Nature Reviews Urology

Pre- and peri-implantation Zika virus infection impairs fetal development by targeting trophectoderm cells

(2019) Lei Tan et al.   Nature Communications

Virus in Semen and the Risk of Sexual Transmission

(2018) Heinz Feldmann   NEW ENGLAND JOURNAL OF MEDICINE

Single-Cell RNA Sequencing Analysis Reveals Sequential Cell Fate Transition during Human Spermatogenesis

(2018) Mei Wang et al.   Cell Stem Cell

Genetic deletion of the Angiotensin-(1–7) receptor Mas leads to a reduced ovulatory rate

(2018) Kinulpe Honorato-Sampaio et al.   PEPTIDES

Semen as virus reservoir?

(2016) Walter D. Cardona Maya et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Protective effect of butylated hydroxytoluene on sperm function in human spermatozoa cryopreserved by vitrification technique

(2014) O. Merino et al.   ANDROLOGIA

Angiotensin-Converting Enzymes Play a Dominant Role in Fertility

(2013) Pei-Pei Pan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The components of the angiotensin-(1-7) system are differentially expressed during follicular wave in cattle

(2013) Marcos Henrique Barreta et al.   JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM

Single-cell RNA-Seq profiling of human preimplantation embryos and embryonic stem cells

(2013) Liying Yan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A reliable procedure for decontamination before thawing of human specimens cryostored in liquid nitrogen: three washes with sterile liquid nitrogen (SLN2)

(2012) Lodovico Parmegiani et al.   FERTILITY AND STERILITY

Angiotensin-converting enzyme 2, angiotensin-(1–7) and Mas: new players of the renin–angiotensin system

(2012) Robson A S Santos et al.   JOURNAL OF ENDOCRINOLOGY

Angiotensin-(1-7), its receptor Mas, and the angiotensin-converting enzyme type 2 are expressed in the human ovary

(2010) Fernando M. Reis et al.   FERTILITY AND STERILITY