Review
Chemistry, Multidisciplinary
Kory Schlingman, Yiting Chen, R. Stephen Carmichael, Tricia Breen Carmichael
Summary: Light-emitting electrochemical cells (LECs) are simple electroluminescent devices that use a mechanism involving both ionic and electronic transport. Unlike organic light-emitting diodes (OLED), LECs have flourished in academic research due to their simple structure and unique features, leading to the development of flexible and stretchable light-emitting devices.
ADVANCED MATERIALS
(2021)
Article
Materials Science, Multidisciplinary
Ulrika Boda, Ioannis Petsagkourakis, Valerio Beni, Peter Andersson Ersman, Klas Tybrandt
Summary: The challenge of high-performance fully printed stretchable OECTs is addressed by developing fully screen-printed stretchable OECTs. Three stretchable functional screen-printing inks are developed, enabling the fabrication of OECTs. The stretchable OECTs show good characteristics and can withstand high strains. An electrochromic smart pixel is demonstrated by connecting a stretchable OECT to a stretchable electrochromic display. The development of screen-printed stretchable electrochemical devices, particularly OECTs, is believed to pave the way for their use in wearable applications and commercial products.
ADVANCED MATERIALS TECHNOLOGIES
(2023)
Article
Polymer Science
Kirill Puchnin, Dmitriy Ryazantsev, Vitaliy Grudtsov, Yaroslav Golubev, Alexander Kuznetsov
Summary: New modified off-stoichiometry thiol-enes polymers (OSTE-MS polymers) were developed by introducing mercaptosilane into the polymer mixture, enabling the polymer to bond with silicon wafers without modifying the wafer surface. Optimized composition for creating 3D polymer structures on a chip was selected and successful fabrication of well type and microfluidic system structures on silicon chips was achieved based on OSTE-MS polymers.
Review
Chemistry, Multidisciplinary
Yi Zhao, Kai-Qi Jin, Jing-Du Li, Kai-Kai Sheng, Wei-Hua Huang, Yan-Ling Liu
Summary: The development of flexible and stretchable electronics has revolutionized biosensor techniques for probing biological systems. Flexible and stretchable electrochemical sensors (FSECSs) enable the in situ quantification of biochemical molecules in different biological entities due to their exceptional sensitivity, fast response, and easy miniaturization. This review discusses the key developments in electrode fabrication and FSECSs functionalization, as well as their applications in exploring the chemical information from different biological entities. Current challenges and future opportunities for FSECSs are also highlighted.
ADVANCED MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Yahao Dai, Shilei Dai, Nan Li, Yang Li, Maximilian Moser, Joseph Strzalka, Aleksander Prominski, Youdi Liu, Qingteng Zhang, Songsong Li, Huawei Hu, Wei Liu, Shivani Chatterji, Ping Cheng, Bozhi Tian, Iain McCulloch, Jie Xu, Sihong Wang
Summary: Organic electrochemical transistors (OECTs) have high amplification and sensitivity to biological signals, making them a promising platform for next-generation bioelectronics. However, achieving seamless tissue-electronics interfaces with softness and stretchability has been a challenge due to the lack of stretchable redox-active semiconducting polymers. This study reports a stretchable semiconductor for OECT devices, which exhibits exceptional stretchability and high OECT performance. The polymer's design features, including a nonlinear backbone architecture, moderate side-chain density, and high molecular weight, enable the combination of stretchability and OECT performance. The highly stretchable polymer semiconductor allows for fabricating intrinsically stretchable OECTs with high transconductance and biaxial stretchability, and demonstrates on-skin electrocardiogram recording with built-in amplification and unprecedented skin conformability.
ADVANCED MATERIALS
(2022)
Review
Chemistry, Multidisciplinary
Yao Yao, Wei Huang, Jianhua Chen, Xiaoxue Liu, Libing Bai, Wei Chen, Yuhua Cheng, Jianfeng Ping, Tobin J. Marks, Antonio Facchetti
Summary: Flexible and stretchable bioelectronics, such as organic electrochemical transistors (OECTs), have received significant attention for in situ monitoring of biological systems. These devices exhibit advantages in biological sensing due to their ionic switching behavior, low driving voltage, and high transconductance. Recent research has focused on developing flexible/stretchable OECTs (FSOECTs) for biochemical and bioelectrical sensors, and this review summarizes the major accomplishments and challenges in this field.
ADVANCED MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Ethan J. Krings, Benjamin D. Hage, Sequoia L. Truong, Kiersten A. Reeser, Eli L. Fox, Matthew G. Snyder, Quentin Walker, Gregory R. Bashford, Eric J. Markvicka
Summary: This study presents a systematic exploration of soft composites with liquid metal fillers dispersed in elastomers to create a stretchable acoustic matching layer. The material achieves a high acoustic impedance (> 440% increase over the polymer matrix), low modulus, and high stretchability. The experiments demonstrate that the material maintains sound transmittance and attenuation even when mechanically strained.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Chemistry, Physical
Yujie Peng, Lin Gao, Changjian Liu, Jinyi Deng, Miao Xie, Libing Bai, Gang Wang, Yuhua Cheng, Wei Huang, Junsheng Yu
Summary: This work demonstrates stretchable synaptic OECTs using a three-dimensional P3HT/SEBS blend porous elastic film which can fully emulate biological synaptic behaviors. The architecture allows for adjustable OECT output and hysteresis, enabling plasticity transition. The stretchable synaptic OECTs exhibit excellent mechanical robustness at a 30% strain and reliable electrical characteristics after 500 stretching cycles. Furthermore, near-ideal weight updates, symmetric long-term potentiation and depression, and image simulation applications are validated.
Review
Energy & Fuels
Erfan Sadeghi, Mohammad Mahdi Gholami, Mohsen Hamzeh, Seyed Mohammad Mahdi Alavi, Mehrdad Saif
Summary: With the automotive industry's shift towards electric vehicles and the consequent reliance on energy storage systems, the interest in Power Electronics Interfaced Electrochemical Impedance Spectroscopy (PEI-EIS) is rapidly growing. This paper provides an engineering perspective on the PEI-EIS process, guiding researchers through the main phases, reviewing recent work, and highlighting the challenging issues encountered. It discusses the often overlooked role of the controller, the generation of required excitation signals by power electronics devices, the type of excitations needed, data measurement, and result presentation. Furthermore, it evaluates the pros and cons of past contributions to PEI-EIS from an engineering viewpoint.
JOURNAL OF ENERGY STORAGE
(2023)
Article
Nanoscience & Nanotechnology
Changjian Liu, Jinyi Deng, Lin Gao, Jingliang Cheng, Yujie Peng, Hongjuan Zeng, Wei Huang, Liang-Wen Feng, Junsheng Yu
Summary: Porous films provide a simple strategy for balancing the electron/hole transport and ion doping/dedoping process in organic electrochemical transistors (OECTs). In this study, a 3D integrated approach was demonstrated to achieve enhanced transconductance (g(m)) and mechanical stretchability by constructing a multilayer breath-figured porous polymer channel. The porous structure not only provides efficient ion-electron coupling and transport pathways, but also offers resistance against mechanical deformation. The results showed that the 3D porous structure enhanced the stretchability and electrical performance of OECTs, making it a promising approach for stretchable electronics.
ADVANCED ELECTRONIC MATERIALS
(2023)
Article
Chemistry, Analytical
Haihong Guo, Changjian Liu, Yujie Peng, Lin Gao, Junsheng Yu
Summary: We proposed breathable OECT-based glucose sensors with a porous structure, realizing optimal breathable and stretchable properties. The sensors exhibit exceptional electrical properties and can retain up to about 44% of their initial performance even at 30% stretching. Furthermore, they show obvious responses to glucose even under 30% strain, with a normalized response of 26% and 21% for 10(-4) M glucose for the pristine sensor and under 30% strain, respectively. This work offers a new strategy for developing advanced breathable and wearable bioelectronics.
Article
Polymer Science
Albert Fabregat-Sanjuan, Xavier Fernandez-Francos, Francesc Ferrando-Piera
Summary: It is essential to control curing rate and exothermicity during the processing of thermosetting composite materials in order to minimize internal stresses and defects. Experimental proof of the concept of sequential heat release for dual-curing thermosets has been demonstrated in this article, showing better control of conversion and temperature profiles during the crosslinking stage.
JOURNAL OF APPLIED POLYMER SCIENCE
(2022)
Article
Physics, Multidisciplinary
Michael Lerond, Arunprabaharan Subramanian, W. G. Skene, Fabio Cicoira
Summary: Stretchable conductors and organic electrochemical transistors were fabricated from PEDOT:Tos nanofibers using a combination of electrospinning, electrode printing, and vapor phase polymerization. The electrical properties of the spun fibers remained stable, allowing the devices to maintain transistor behavior up to 50% strain.
FRONTIERS IN PHYSICS
(2021)
Article
Chemistry, Physical
Zhiwei Gong, Wei Xu, N. A. Liedienov, D. S. Butenko, I. Zatovsky, I. A. Gural'skiy, Ziyu Wei, Quanjun Li, Bingbing Liu, Yu A. Batman, A. Pashchenko, G. G. Levchenko
Summary: Comprehensive studies of the physical and chemical properties of manganites are required for their prospects in modern technologies. This study investigates the control of the magnetocaloric effect of LMO under changing internal and external conditions and evaluates its potential applications as an electrocatalyst in the OER process.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2022)
Article
Chemistry, Multidisciplinary
Jing Li, Guoyun Zhou, Yan Hong, Chia-Yun Chen, Wei He, Shouxu Wang, Yuanming Chen, Chong Wang, Yukai Sun, Chingping Wong
Summary: The new design of copper conductive patterns on cloth fibers achieves reliable signal transmission with excellent stretchability and reliability.
ADVANCED MATERIALS INTERFACES
(2022)
Article
Pharmacology & Pharmacy
Iiro Kiiski, Elisa Ollikainen, Sanna Artes, Paivi Jarvinen, Ville Jokinen, Tiina Sikanen
Summary: This study introduces a microfluidic reactor design using immobilized human liver microsomes to study UGT-mediated drug clearance under flow-through conditions. Characterization of the microreactor performance is done using glucuronidation of two model reactions. Conducting UGT metabolism assays under flow conditions facilitates in-depth mechanistic studies and may shed light on UGT latency.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2021)
Article
Chemistry, Multidisciplinary
Paavo Raittinen, Pinja Elomaa, Paivi Saavalainen, Ville Jokinen
Summary: Single cell trapping is demonstrated on superhydrophobic-superhydrophilic patterned microarrays. The optimal method for trapping single cells is found to be using superhydrophilic spots that are twice the size of the cells. The trapping is based on size exclusivity rather than heavy dilution of the cell suspension and relying on Poisson statistics.
ADVANCED MATERIALS INTERFACES
(2021)
Article
Nanoscience & Nanotechnology
Hamidreza Daghigh Shirazi, Yujiao Dong, Jukka Niskanen, Chiara Fedele, Arri Priimagi, Ville P. Jokinen, Jaana Vapaavuori
Summary: A simple hierarchical surface patterning method is proposed by combining buckling instability and azopolymer-based surface relief grating inscription, allowing for the fabrication of surfaces with different length scales and the tuning of wetting properties. The demonstrated fine-tuning of the surface patterns may be useful in optimizing material properties related to surfaces and producing substrates of potential interest in mechanobiology and tissue engineering.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Environmental Sciences
Tea L. M. Pihlaja, Sanna M. Niemissalo, Tiina M. Sikanen
Summary: The study found that antimicrobials, commonly found in the environment, can accumulate in fish and affect the CYP system in rainbow trout liver, potentially leading to broad CYP inactivation and bioaccumulation risk.
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Sara Feola, Markus Haapala, Karita Peltonen, Cristian Capasso, Beatriz Martins, Gabriella Antignani, Antonio Federico, Vilja Pietiainen, Jacopo Chiaro, Michaela Feodoroff, Salvatore Russo, Antti Rannikko, Manlio Fusciello, Satu Koskela, Jukka Partanen, Firas Hamdan, Sari M. Tahka, Erkko Ylosmaki, Dario Greco, Mikaela Gronholm, Tuija Kekarainen, Masoumeh Eshaghi, Olga L. Gurvich, Seppo Yla-Herttuala, Rui M. M. Branca, Janne Lehtio, Tiina M. Sikanen, Vincenzo Cerullo
Summary: This study successfully identified and characterized tumor-specific ligands using a microfluidic-based chip, highlighting the potential for personalized cancer therapeutic vaccine design. The developed technology showed improved efficiency in isolating peptides and has the capability for high-throughput analysis with potential clinical applications.
Article
Chemistry, Physical
Yalda Shoja, Noora Isoaho, Ville Jokinen, Sami Franssila
Summary: TiN thin films are being studied as electrochemical signal transducers for neurotransmitter dopamine (DA) detection, with a focus on investigating the impact of oxygen functionalities on the electrochemical performance of the films. Surface modification of TiN thin films is explored through a hybrid approach of microfabrication and nanocomposite methods. The developed sensor shows high sensitivity and selectivity for DA detection, with good stability and a low detection limit.
APPLIED SURFACE SCIENCE
(2022)
Article
Materials Science, Multidisciplinary
Jussi Isokuortti, Iiro Kiiski, Tiina Sikanen, Nikita Durandin, Timo Laaksonen
Summary: The potential of triplet fusion photon upconversion (TF-UC) in biomedicine and life sciences is restricted by its sensitivity to oxygen. This study demonstrates the use of microfluidic chips made of oxygen depleting materials to evaluate the oxygen tolerability of different nanocarriers in physiological oxygen levels. The addition of oxygen scavengers in the nanocarrier's oil phase significantly improves their ability to tolerate oxygen.
JOURNAL OF MATERIALS CHEMISTRY C
(2022)
Article
Chemistry, Multidisciplinary
Heikki A. Nurmi, Cunming Yu, Dmytro Toptunov, Robin H. A. Ras, Ville Jokinen
Summary: Lubrication is an important method to reduce friction. The focus is now shifting towards environmentally-friendly green lubrication. This study introduces a novel concept for green lubrication using a bilayer of water and ambient air as the lubricant, achieving superlubricity.
ADVANCED MATERIALS INTERFACES
(2022)
Article
Environmental Sciences
Laura M. Langan, Martin Paparella, Natalie Burden, Lisa Constantine, Luigi Margiotta-Casaluci, Thomas H. Miller, S. Jannicke Moe, Stewart F. Owen, Alexandra Schaffert, Tiina Sikanen
Summary: This article reviews the current level of knowledge around nonanimal testing methods for hazard and exposure assessment, and environmental and health risks of pharmaceuticals and personal care products in the natural environment. It highlights advancements in aquatic environmental risk assessment and emphasizes the need for a global and inclusive approach to establish consensus for regulatory assessment and decision-making.
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Calvin Thenarianto, Xue Qi Koh, Marcus Lin, Ville Jokinen, Dan Daniel
Summary: A water droplet can rebound multiple times on superhydrophobic surfaces, and the energy loss during such rebounds depends on the ratio of rebound speed to initial impact speed. We conducted experiments on different superhydrophobic surfaces with droplets of various sizes and proposed scaling laws to explain the nonmonotonic relationship between the energy loss and impact speed. At low impact speeds, the energy loss is influenced by contact-line pinning and the surface wetting properties, while at high impact speeds, it is dominated by inertial-capillary effects.
Article
Chemistry, Multidisciplinary
Sakari Lepikko, Ygor Morais Jaques, Muhammad Junaid, Matilda Backholm, Jouko Lahtinen, Jaakko Julin, Ville Jokinen, Timo Sajavaara, Maria Sammalkorpi, Adam S. Foster, Robin H. A. Ras
Summary: This study challenges the traditional assumption of surface heterogeneity as the major factor that affects the motion of liquid droplets on solid surfaces. It reveals a counterintuitive mechanism of slipperiness that is not expected based on the chemical heterogeneity of the surface. This finding opens up new avenues for enhancing the mobility of droplets.
Article
Chemistry, Multidisciplinary
Mohammad Awashra, Pinja Elomaa, Tuomas Ojalehto, Paivi Saavalainen, Ville Jokinen
Summary: This paper presents a method of using superhydrophilic/superhydrophobic micropatterned surfaces to create droplet arrays for RNA analysis. It overcomes the challenges brought by different fluid properties and allows the formation of droplets from a broader range of biofluids by using a prewetting and protective oil step. The method is applied to SARS-CoV-2 virus nucleic acid detection.
ADVANCED MATERIALS INTERFACES
(2023)
Article
Chemistry, Physical
Arthur Vieira, Wenjuan Cui, Ville Jokinen, Robin H. A. Ras, Quan Zhou
Summary: Many natural and artificial water-repellent surfaces have micro- and nano-roughness and their wetting properties can be determined by observing the contact angles at the liquid-solid interface. However, a generally applicable method to directly observe the moving contact lines on such surfaces is missing. In this study, we demonstrate that a transparent droplet probe combined with a conventional optical microscope can accurately quantify the contact angles and contact area on water-repellent surfaces.
Article
Biochemical Research Methods
Iiro Kiiski, Paivi Jarvinen, Elisa Ollikainen, Ville Jokinen, Tiina Sikanen
Summary: This study utilized the oxygen scavenging property of off-stoichiometric thiol-enes (OSTE) to create physiologically relevant oxygen concentrations in microfluidic immobilized enzyme reactors. The results showed that the oxygen scavenging rate of OSTE depended on the type and amount of thiol monomer used, and the surface-to-volume ratio of the chip design. The mechanism of OSTE-induced oxygen scavenging was examined in depth, providing insights for precise adjustment of oxygen concentrations in microfluidic devices.
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)