Article
Chemistry, Analytical
Bingxi Feng, Yue Wu, Yuan Ren, YiQing Chen, Kaiping Yuan, Yonghui Deng, Jing Wei
Summary: A self-template synthesis strategy using plant polyphenol as a chelating agent was developed to successfully prepare mesoporous Au-SnO2 nanospheres for low-temperature detection of TEA. The nanospheres showed high response, low detection limit, and fast response time. This strategy has the potential to enhance the sensing performance of gas sensors.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Chemistry, Multidisciplinary
Tariq Aqeel, Vardan Galstyan, Elisabetta Comini, Ali Bumajdad
Summary: This study successfully enhanced the conductivity and sensitivity of tin dioxide to certain gases by synthesizing antimony-containing mesoporous tin dioxide materials, which provides highly conductive oxide nanomaterials for chemical gas sensing devices manufacturing.
ARABIAN JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Physical
Jiarui Huang, Chunyu Meng, Hui Wang, Haibo Ren, Xiaojing Lu, Sang Woo Joo
Summary: In this study, cross-linked porous tin dioxide nanosheets were successfully synthesized using three-dimensional reduced graphene oxide as a template. The resulting nanosheets exhibited high sensitivity to toxic organic vapors, making them promising candidates for practical detectors of volatile organic compounds.
JOURNAL OF ALLOYS AND COMPOUNDS
(2022)
Article
Polymer Science
Qiaohua Feng, Huanhuan Zhang, Yunbo Shi, Xiaoyu Yu, Guangdong Lan
Summary: This study successfully prepared PANI/SnO2 hybrid material for the detection of ammonia and benzene vapors, which showed good gas adsorption performance and linear response sensitivity at room temperature. The doped SnO2 significantly affected the sensitivity, response time, and recovery time of the PANI material.
Article
Chemistry, Multidisciplinary
Bingxi Feng, Youyou Feng, Yuxin Li, Yaqiong Su, Yonghui Deng, Jing Wei
Summary: The study demonstrated the fabrication of spherical mesoporous Ag2O/SnO2 sensing materials using silver/tin-polyphenol hybrid spheres as sacrificial templates. These materials exhibit uniform particle size, large pore size, high specific surface area, excellent response to formaldehyde at low temperatures, and exceptional selectivity towards interfering gases. Additionally, theoretical calculations suggest that the addition of Ag2O significantly enhances the adsorption energy towards formaldehyde, improving the overall sensing performance.
Article
Chemistry, Physical
Fanli Meng, Zhijia Liao, Chaoyang Xing, Zhenyu Yuan, Renze Zhang, Hongmin Zhu, Jin Li
Summary: SnO2/SiO2 nanocomposites were prepared by the sol-gel method, demonstrating superior gas sensing properties and the ability to detect triethylamine at a minimum concentration of 500 ppb.
JOURNAL OF ALLOYS AND COMPOUNDS
(2022)
Article
Chemistry, Physical
V. Ambardekar, T. Bhowmick, P. P. Bandyopadhyay, S. B. Majumder
Summary: This study compared the gas sensing characteristics of plasma sprayed tin dioxide thick film with tin dioxide bulk sensor in the presence of hydrogen and carbon monoxide gases. The results showed that the thick film exhibited superior hydrogen gas response, shorter response time, and recovery time, which were attributed to its porous morphology and small-sized particulates.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2021)
Article
Chemistry, Physical
Ping Li, Youyou Feng, Dong Cheng, Jing Wei
Summary: Mesoporous vanadium oxide nanospheres with small, uniform and adjustable particle size, large mesopore size, and high specific surface area were successfully synthesized via a self-template strategy. These nanospheres can effectively inhibit bacterial growth.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Article
Chemistry, Physical
Jing-Shuo Liu, Ning Wang, Xian-Fa Zhang, Zhao-Peng Deng, Ying-Ming Xu, Li-Hua Huo, Shan Gao
Summary: Mesoporous CeO2-550 nanosheets prepared by a simple method exhibit superior mesoporous structure and gas-sensing properties, making them suitable for detecting trace p-xylene vapors.
JOURNAL OF ALLOYS AND COMPOUNDS
(2021)
Article
Polymer Science
Irina Kononova, Vyacheslav Moshnikov, Pavel Kononov
Summary: Porous nanocomposites using two and three-component systems were created for gas sensors with the sol-gel method. The Langmuir model and the Brunauer-Emmett-Teller theory were used for calculations to understand the physical-chemical processes during gas adsorption. X-ray diffraction, thermogravimetric analysis, and other techniques were used to analyze the interaction between components and determine optimal annealing temperature. Introduction of a semiconductor additive increased the sensitivity of the nanostructured layers to reductional reagent gases.
Article
Nanoscience & Nanotechnology
Lanpeng Guo, Hongping Liang, Dongmin An, Huimin Yang
Summary: Noble metal doping, such as silver (Ag), is an efficient way to improve the sensing performance of metal oxide semiconductor nanomaterials. In this study, uniform Ag-doped SnO2 nanoparticles with a diameter of less than 10 nm were successfully synthesized. Compared to pure SnO2-based sensors, the Ag/SnO2-based sensors showed enhanced sensitivity and selectivity towards ethanol, especially the 6% Ag/SnO2-based sensor with a high response (Ra/Rg = 135) to 50 ppm ethanol at 180 degrees C. These results suggest that Ag-doped SnO2 nanoparticles have potential application for ethanol sensors.
PHYSICA E-LOW-DIMENSIONAL SYSTEMS & NANOSTRUCTURES
(2023)
Article
Chemistry, Applied
Alka Singh, Mansi Vats, Satyabrata Mohapatra, Monika Tomar, Arijit Chowdhuri, Vaishali Singh
Summary: The work demonstrates the synthesis of mesoporous tin oxide (m-SnO2) with enhanced gas sensing performance for Nitrogen Dioxide (NO2) by using Cetyl Trimethyl Ammonium Bromide (CTAB) as the soft template. The resulting sensor exhibits a high response and good repeatability and selectivity towards NO2 gas. The enhanced sensor performance is attributed to the large surface area, mesoporous structure, and small crystallite size of the m-SnO2 material.
JOURNAL OF POROUS MATERIALS
(2023)
Article
Chemistry, Analytical
Run-Hui Wang, Wei Wen, Shilie Zheng, Zhizhen Ye, Jin-Ming Wu
Summary: In this study, a layered mesoporous aggregate of tin oxide nanocrystals with high specific surface area and mesoporous structure was synthesized. The tin oxide showed high ethanol sensing performance at low temperatures, with high selectivity and stability. The ethanol sensing mechanism changed with increasing operating temperature.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Review
Chemistry, Inorganic & Nuclear
Gen Wang, Shengjiong Yang, Li Cao, Pengkang Jin, Xiangkang Zeng, Xiwang Zhang, Jing Wei
Summary: Chemiresistive gas sensors based on semiconducting metal oxides (SMOs) are widely used in various fields, but developing sensors with high selectivity and low working temperature remains a challenge. Metal-organic frameworks (MOFs) derived SMOs have shown promise due to their mesoporous structure and unique morphology. This review systematically summarizes recent developments in this area and discusses strategies for enhancing sensing performance, such as constructing novel nanostructures and combining with highly-conductive materials.
COORDINATION CHEMISTRY REVIEWS
(2021)
Article
Chemistry, Analytical
Jingyu Zhang, Meng Kong, Kai Li, Xi Chen, Xin Li, Lu Yue, Xiuli Yang, Rongfeng Guan, Wenhui Zhang
Summary: Hierarchical S-doped In2O3 networks were synthesized with graphene oxide as a template and annealed. The effects of graphene oxide and annealing temperature on the morphology and phase of the samples were investigated. The hierarchical S-doped In2O3 networks consisted of nanosheets and microspheres assembled with nanowires and nanoparticles. The annealed hierarchical S-doped In2O3 networks at 500 degrees C showed the highest response (Ra/Rg) of 74.4 towards 50 ppm ethanol at 180 degrees C, which was approximately 2 times higher than that of S-doped In2O3 micro pompons prepared without graphene oxide. Moreover, the hierarchical In2O3 networks exhibited excellent selectivity and good stability to ethanol, which may be attributed to their unique hierarchical networks, high specific surface area (295.23 m2/g), and sulfur doping.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Chemistry, Physical
Youyou Feng, Jing Qin, Yu Zhou, Qin Yue, Jing Wei
Summary: The combination of mesoporous Fe-N-C SAzyme with photothermal treatment enhances the catalytic performance, resulting in a more effective antibacterial treatment compared to using single antibacterial methods.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Article
Chemistry, Analytical
Yiqing Chen, Yuxin Li, Bingxi Feng, Yue Wu, Yongheng Zhu, Jing Wei
Summary: A new gas sensor based on mesoporous Au-ZnO nanospheres was developed for the detection of seafood quality. The sensor showed higher response and shorter response time compared to traditional methods, and demonstrated better selectivity and sensitivity for detecting TMA.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Chemistry, Analytical
Bingxi Feng, Yue Wu, Yuan Ren, YiQing Chen, Kaiping Yuan, Yonghui Deng, Jing Wei
Summary: A self-template synthesis strategy using plant polyphenol as a chelating agent was developed to successfully prepare mesoporous Au-SnO2 nanospheres for low-temperature detection of TEA. The nanospheres showed high response, low detection limit, and fast response time. This strategy has the potential to enhance the sensing performance of gas sensors.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Nanoscience & Nanotechnology
Bingxi Feng, Yue Wu, Yiqing Chen, Kaiping Yuan, Qin Yue, Yonghui Deng, Jing Wei
Summary: In this study, mesoporous Au-In2O3 spheres were synthesized by direct thermal decomposition of metal-polyphenol hybrids and used for room-temperature detection of triethylamine vapor. The modified Au-In2O3 spheres exhibited a high response and stability at a lower working temperature, making them suitable for the fabrication of gas sensors with low energy consumption and high sensitivity.
ACS APPLIED NANO MATERIALS
(2022)
Review
Chemistry, Inorganic & Nuclear
Youyou Feng, Ping Li, Jing Wei
Summary: Metal-organic hybrids, especially derived from plant polyphenols, have shown great potential in the field of functional nanoporous materials due to their tunable compositions and structures. These materials can be prepared in various forms, such as metal-polyphenol coordination polymers, mesoporous carbon materials, and mesoporous metal oxide spheres, with applications in energy, environment, sensor, and biomedicine fields. The use of plant polyphenols as a sustainable carbon source and molecular glue allows for the creation of diverse functional porous materials, providing promising prospects for future research and development.
COORDINATION CHEMISTRY REVIEWS
(2022)
Article
Chemistry, Physical
Yaozhen Huang, Jing Peng, Yang Gao, Zheng Wang, Jing Li, Feng Li
Summary: By growing ternary FeCo2Mo5 LDH nanosheets on the surface of vulcanized Ni foam, the mass and electron transport for the oxygen evolution reaction (OER) can be improved. This research has important implications for the design of cheap and efficient catalytic electrodes.
ACS APPLIED ENERGY MATERIALS
(2022)
Review
Biochemical Research Methods
Jin Zhang, Jing Xue, Ningfeng Luo, Feng Chen, Badong Chen, Yongxi Zhao
Summary: Single-cell profiling is crucial for understanding cellular heterogeneity and cell fate. Microfluidics has emerged as an optimal tool for single-cell profiling due to its high throughput and automation advantages. Among different microfluidic platforms, microwell array chips offer simplicity and easy integration with in situ analysis, making them ideal for single-cell studies. This review summarizes recent advances in single-cell analysis based on microwell array chips, including chip design and preparation, cell capture and lysis strategies, as well as advanced analysis of single-cell proteins, nucleic acids, and metabolites. The challenges and opportunities in the development of microwell-based single-cell analysis are also discussed.
Article
Biochemistry & Molecular Biology
Xiaowen Cao, Feng Chen, Jing Xue, Yue Zhao, Min Bai, Yongxi Zhao
Summary: Here, we present a hierarchical DNA branch assembly-encoded fluorescent nanoladders for denoised and highly multiplexed signal amplification of single-cell transcripts. Our method achieves independent RNA-primed rolling circle amplification without nonspecific amplification and allows for programmable DNA branch assembly to encode virtual signals for visualizing numbers of targets. We demonstrate accurate RNA profiling in different cancer cells and reveal diverse localization patterns for spatial regulation of transcripts.
NUCLEIC ACIDS RESEARCH
(2023)
Article
Chemistry, Multidisciplinary
Siqi Xie, Cheng Zhao, Jiabin Shen, Jing Wei, Haiquan Liu, Yingjie Pan, Yong Zhao, Yongheng Zhu
Summary: Nowadays, indirectly detecting the metabolite biomarker of L. monocytogenes, 3-hydroxy-2-butanone, has been proven effective to evaluate the contamination of L. monocytogenes. In this study, low-cost and highly sensitive and selective 3-hydroxy-2-butanone sensors based on bimetallic AuPd decorated hierarchical flower-like WO3 nanospheres have been proposed. These sensors showed outstanding selectivity, rapid response/recovery, and a low detection limit, enabling the evaluation of L. monocytogenes with high sensitivity and specificity.
Article
Chemistry, Physical
Gen Wang, Ke Wang, Zhuoyue Liu, Youyou Feng, Shengjiong Yang, Yaqiong Su, Xufang Qian, Pengkang Jin, Jing Wei
Summary: This study designs NiO nanospheres with hollow multi-shelled structure as a nanoreactor for the activation of peroxydisulfate to improve decomposition efficiency. The 3-shelled NiO HoMS exhibits enhanced kinetic rate (0.08 min-1) and mineralization degree (79.2%) compared to the 2-shelled NiO HoMS (0.04 min-1, 50%) and NiO nanoparticles (0.01 min-1, 29.8%) for the degradation of bis-phenol A. The hollow multi-shelled structure increases the accessibility of oxygen vacancy and enriches the local concentration of reactants, contributing to the enhanced catalytic efficiency.
APPLIED CATALYSIS B-ENVIRONMENTAL
(2023)
Article
Biophysics
Yuxin Li, Ping Li, Yiqing Chen, Yue Wu, Jing Wei
Summary: In this study, a structurally tunable nanomaterials platform for indirect detection of glutathione (GSH) through surface enhanced Raman scattering (SERS) was developed. The CuTA@Ag nanostructures demonstrated satisfactory SERS performance with a low detection limit of 10-7 M for GSH, and were able to accurately and reliably detect the glutathione content in cancer cells.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Chemistry, Multidisciplinary
Ping Li, Bingxi Feng, Youyou Feng, Guoxin Song, Xiaoli Cheng, Yonghui Deng, Jing Wei
Summary: A highly sensitive glutaraldehyde gas sensor was developed using mesoporous lanthanum-doped SnO2 spheres, which exhibited a high specific surface area and highly crystalline framework. The sensor showed a high response, rapid response time, and low limit of detection, enabling effective detection of glutaraldehyde disinfectants.
Review
Biochemical Research Methods
Huan Liu, Lang Nan, Feng Chen, Yue Zhao, Yongxi Zhao
Summary: Droplet microfluidics coupled with artificial intelligence (AI) provides new opportunities for autonomous system optimization and control, enabling innovative functions and applications. This review elucidates the principles and functions of AI, and summarizes the intelligent microfluidic systems used in droplet generation, material synthesis, and biological analysis. The current challenges in combining AI and droplet microfluidics more widely are discussed, along with potential strategies to tackle these challenges. This review aims to deepen our understanding of intelligent droplet microfluidics and inspire functional designs for emerging demands.
Article
Chemistry, Multidisciplinary
Xueqi Zhao, Yue Zhao, Jing Xue, Min Bai, Feng Chen, Ying Sun, Daqian Song, Yongxi Zhao
Summary: This paper reviews the research progress of nucleic acids-encoded amplification in single-cell fluorescence imaging, highlighting its advantages in sensitive and multiplex imaging of low abundance targets and discussing the challenges of multiplex detection in living cells and future development directions.
CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE
(2022)
Review
Materials Science, Multidisciplinary
You-you Feng, Yi-qing Chen, Zheng Wang, Jing Wei
Summary: Mesoporous carbon materials, with high specific surface area, tunable surface chemistry and pore structure, and good chemical stability and conductivity, have gained significant attention in environmental remediation, industrial catalysis, energy conversion, and storage. Plant polyphenols, a universal biomass with low cost, nontoxicity, and sustainability, are suitable carbon sources for the synthesis of mesoporous carbon composites due to their good adhesion and metal chelating ability. This article provides methods for synthesizing different forms of mesoporous carbon from plant polyphenols and summarizes their applications in environmental and energy studies.
NEW CARBON MATERIALS
(2022)
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)