Analysis of multispectral imaging with the AstroPath platform informs efficacy of PD-1 blockade
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Analysis of multispectral imaging with the AstroPath platform informs efficacy of PD-1 blockade
Authors
Keywords
-
Journal
SCIENCE
Volume 372, Issue 6547, Pages eaba2609
Publisher
American Association for the Advancement of Science (AAAS)
Online
2021-06-11
DOI
10.1126/science.aba2609
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Neoadjuvant checkpoint blockade for cancer immunotherapy
- (2020) Suzanne L. Topalian et al. SCIENCE
- The Society for Immunotherapy in Cancer statement on best practices for multiplex immunohistochemistry (IHC) and immunofluorescence (IF) staining and validation
- (2020) Janis M Taube et al. Journal for ImmunoTherapy of Cancer
- A dynamic CD2-rich compartment at the outer edge of the immunological synapse boosts and integrates signals
- (2020) Philippos Demetriou et al. NATURE IMMUNOLOGY
- Checkpoint Blockade Immunotherapy Induces Dynamic Changes in PD-1−CD8+ Tumor-Infiltrating T Cells
- (2019) Sema Kurtulus et al. IMMUNITY
- Efficacy of PD-1 blockade in cervical cancer is related to a CD8+FoxP3+CD25+ T-cell subset with operational effector functions despite high immune checkpoint levels
- (2019) A. M. Heeren et al. Journal for ImmunoTherapy of Cancer
- Neoadjuvant nivolumab modifies the tumor immune microenvironment in resectable glioblastoma
- (2019) Kurt A. Schalper et al. NATURE MEDICINE
- Siglec-15 as an immune suppressor and potential target for normalization cancer immunotherapy
- (2019) Jun Wang et al. NATURE MEDICINE
- B7-H3 expression in Merkel cell carcinoma-associated endothelial cells correlates with locally aggressive primary tumor features and increased vascular density
- (2019) Phyu P Aung et al. CLINICAL CANCER RESEARCH
- Comparison of Biomarker Modalities for Predicting Response to PD-1/PD-L1 Checkpoint Blockade
- (2019) Steve Lu et al. JAMA Oncology
- Transcriptional Basis of Mouse and Human Dendritic Cell Heterogeneity
- (2019) Chrysothemis C. Brown et al. CELL
- Inhibitory receptors and ligands beyond PD-1, PD-L1 and CTLA-4: breakthroughs or backups
- (2019) Lawrence P. Andrews et al. NATURE IMMUNOLOGY
- A transcriptionally and functionally distinct PD-1+ CD8+ T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade
- (2018) Daniela S. Thommen et al. NATURE MEDICINE
- MHC proteins confer differential sensitivity to CTLA-4 and PD-1 blockade in untreated metastatic melanoma
- (2018) Scott J. Rodig et al. Science Translational Medicine
- Quantitative Analysis of Immune Infiltrates in Primary Melanoma
- (2018) Robyn D. Gartrell et al. Cancer Immunology Research
- Effect of neoadjuvant chemotherapy on the immune microenvironment in non–small cell lung carcinomas as determined by multiplex immunofluorescence and image analysis approaches
- (2018) Edwin R. Parra et al. Journal for ImmunoTherapy of Cancer
- A Structured Tumor-Immune Microenvironment in Triple Negative Breast Cancer Revealed by Multiplexed Ion Beam Imaging
- (2018) Leeat Keren et al. CELL
- Multidimensional, quantitative assessment of PD-1/PD-L1 expression in patients with Merkel cell carcinoma and association with response to pembrolizumab
- (2018) Nicolas A. Giraldo et al. Journal for ImmunoTherapy of Cancer
- Eight-Color Multiplex Immunohistochemistry for Simultaneous Detection of Multiple Immune Checkpoint Molecules within the Tumor Microenvironment
- (2017) Mark A. J. Gorris et al. JOURNAL OF IMMUNOLOGY
- Implications of the tumor immune microenvironment for staging and therapeutics
- (2017) Janis M Taube et al. MODERN PATHOLOGY
- Elements of cancer immunity and the cancer–immune set point
- (2017) Daniel S. Chen et al. NATURE
- Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade
- (2017) Dung T. Le et al. SCIENCE
- Validation of multiplex immunofluorescence panels using multispectral microscopy for immune-profiling of formalin-fixed and paraffin-embedded human tumor tissues
- (2017) Edwin R. Parra et al. Scientific Reports
- Quantitative Multiplex Immunohistochemistry Reveals Myeloid-Inflamed Tumor-Immune Complexity Associated with Poor Prognosis
- (2017) Takahiro Tsujikawa et al. Cell Reports
- Early Effector T Lymphocytes Coexpress Multiple Inhibitory Receptors in Primary Non–Small Cell Lung Cancer
- (2016) Elena Tassi et al. CANCER RESEARCH
- PD-1/PD-L1 inhibitors
- (2015) Joel Sunshine et al. CURRENT OPINION IN PHARMACOLOGY
- Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer
- (2015) N. A. Rizvi et al. SCIENCE
- Principles of Analytic Validation of Immunohistochemical Assays: Guideline From the College of American Pathologists Pathology and Laboratory Quality Center
- (2014) Patrick L. Fitzgibbons et al. ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE
- Progenitor and Terminal Subsets of CD8+ T Cells Cooperate to Contain Chronic Viral Infection
- (2012) M. A. Paley et al. SCIENCE
- Colocalization of Inflammatory Response with B7-H1 Expression in Human Melanocytic Lesions Supports an Adaptive Resistance Mechanism of Immune Escape
- (2012) J. M. Taube et al. Science Translational Medicine
- Tumor-Reactive CD8+ Early Effector T Cells Identified at Tumor Site in Primary and Metastatic Melanoma
- (2010) A. Anichini et al. CANCER RESEARCH
- CD8+Foxp3+ tumor infiltrating lymphocytes accumulate in the context of an effective anti-tumor response
- (2010) Dung T. Le et al. INTERNATIONAL JOURNAL OF CANCER
- Selective expansion of a subset of exhausted CD8 T cells by PD-L1 blockade
- (2008) S. D. Blackburn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now