Preventing type 1 diabetes in childhood

An Age-Related Exponential Decline in the Risk of Multiple Islet Autoantibody Seroconversion During Childhood

(2021) Ezio Bonifacio et al.   DIABETES CARE

Teplizumab improves and stabilizes beta cell function in antibody-positive high-risk individuals

(2021) Emily K. Sims et al.   Science Translational Medicine

Anti-interleukin-21 antibody and liraglutide for the preservation of β-cell function in adults with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled, phase 2 trial

(2021) Matthias von Herrath et al.   Lancet Diabetes & Endocrinology

Yield of a Public Health Screening of Children for Islet Autoantibodies in Bavaria, Germany

(2020) Anette-Gabriele Ziegler et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Prediction and Prevention of Type 1 Diabetes

(2020) Marina Primavera et al.   Frontiers in Endocrinology

A hexavalent Coxsackievirus B vaccine is highly immunogenic and has a strong protective capacity in mice and nonhuman primates

(2020) V. M. Stone et al.   Science Advances

Efficacy of GAD-alum immunotherapy associated with HLA-DR3-DQ2 in recently diagnosed type 1 diabetes

(2020) Ulf Hannelius et al.   DIABETOLOGIA

A combined risk score enhances prediction of type 1 diabetes among susceptible children

(2020) Lauric A. Ferrat et al.   NATURE MEDICINE

Cognitive Function Following Diabetic Ketoacidosis in Children With New-Onset or Previously Diagnosed Type 1 Diabetes

(2020) Simona Ghetti et al.   DIABETES CARE

Clinical Impact of Residual C-Peptide Secretion in Type 1 Diabetes on Glycemia and Microvascular Complications

(2020) Anita Jeyam et al.   DIABETES CARE

Golimumab and Beta-Cell Function in Youth with New-Onset Type 1 Diabetes

(2020) Teresa Quattrin et al.   NEW ENGLAND JOURNAL OF MEDICINE

Demographic characteristics and acute complications among adults with type 1 diabetes: Comparison of two multicentre databases from Germany and the United States

(2020) Alexander J. Eckert et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Development and Standardization of an Improved Type 1 Diabetes Genetic Risk Score for Use in Newborn Screening and Incident Diagnosis

(2019) Seth A. Sharp et al.   DIABETES CARE

State of Type 1 Diabetes Management and Outcomes from the T1D Exchange in 2016–2018

(2019) Nicole C. Foster et al.   Diabetes Technology & Therapeutics

Disease-Modifying Therapies in Type 1 Diabetes: A Look into the Future of Diabetes Practice

(2019) Carla Greenbaum et al.   DRUGS

Age, HLA, and Sex Define a Marked Risk of Organ-Specific Autoimmunity in First-Degree Relatives of Patients With Type 1 Diabetes

(2019) Christiane Winkler et al.   DIABETES CARE

An Anti-CD3 Antibody, Teplizumab, in Relatives at Risk for Type 1 Diabetes

(2019) Kevan C. Herold et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification of infants with increased type 1 diabetes genetic risk for enrollment into Primary Prevention Trials—GPPAD‐02 study design and first results

(2019) Christiane Winkler et al.   PEDIATRIC DIABETES

Oral insulin therapy for primary prevention of type 1 diabetes in infants with high genetic risk: the GPPAD-POInT (global platform for the prevention of autoimmune diabetes primary oral insulin trial) study protocol

(2019) Anette-Gabriele Ziegler et al.   BMJ Open

Microbiome and type 1 diabetes

(2019) Heli Siljander et al.   EBioMedicine

Longitudinal Changes in Continuous Glucose Monitoring Use Among Individuals With Type 1 Diabetes: International Comparison in the German and Austrian DPV and U.S. T1D Exchange Registries

(2019) Kellee M. Miller et al.   DIABETES CARE

A novel LIPS assay for insulin autoantibodies

(2018) Daniela Liberati et al.   ACTA DIABETOLOGICA

Understanding Pre-Type 1 Diabetes: The Key to Prevention

(2018) Laura M. Jacobsen et al.   Frontiers in Endocrinology

Antigen-based immune modulation therapy for type 1 diabetes: the era of precision medicine

(2018) Bart O Roep et al.   Lancet Diabetes & Endocrinology

Metabolic and immune effects of immunotherapy with proinsulin peptide in human new-onset type 1 diabetes

(2017) Mohammad Alhadj Ali et al.   Science Translational Medicine

Childhood adiposity and risk of type 1 diabetes: A Mendelian randomization study

(2017) J. C. Censin et al.   PLOS MEDICINE

Therapeutic anti-CD3 monoclonal antibodies: from bench to bedside

(2016) Chantal Kuhn et al.   Immunotherapy

Genetic risk factors for type 1 diabetes

(2016) Flemming Pociot et al.   LANCET

Staging Presymptomatic Type 1 Diabetes: A Scientific Statement of JDRF, the Endocrine Society, and the American Diabetes Association

(2015) Richard A. Insel et al.   DIABETES CARE

Predictors of Progression From the Appearance of Islet Autoantibodies to Early Childhood Diabetes: The Environmental Determinants of Diabetes in the Young (TEDDY)

(2015) Andrea K. Steck et al.   DIABETES CARE

The 6 year incidence of diabetes-associated autoantibodies in genetically at-risk children: the TEDDY study

(2015) Jeffrey P. Krischer et al.   DIABETOLOGIA

The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study at 30 Years: Overview

(2013) David M. Nathan et al.   DIABETES CARE

Seroconversion to Multiple Islet Autoantibodies and Risk of Progression to Diabetes in Children

(2013) Anette G. Ziegler et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Differential Response of Regulatory and Conventional CD4+ Lymphocytes to CD3 Engagement: Clues to a Possible Mechanism of Anti-CD3 Action?

(2013) L. Li et al.   JOURNAL OF IMMUNOLOGY

Breast-Feeding and Childhood-Onset Type 1 Diabetes: A pooled analysis of individual participant data from 43 observational studies

(2012) C. R. Cardwell et al.   DIABETES CARE

Reduced Prevalence of Diabetic Ketoacidosis at Diagnosis of Type 1 Diabetes in Young Children Participating in Longitudinal Follow-Up

(2011) H. Elding Larsson et al.   DIABETES CARE