Article
Engineering, Biomedical
Baojin Tan, Chao Zhao, Jing Wang, Aliya Tiemuer, Yuanyuan Zhang, Hui Yu, Yi Liu
Summary: In this study, tumor microenvironment-activatable self-assembling organic nanotheranostics were synthesized for precise tumor targeting and upconversion image-guided photothermal therapy. The nanotheranostics showed high sensitivity and selectivity in the acidic tumor microenvironment, allowing for enhanced upconversion luminescence and photothermal effect. This research provides a new approach for the development of activatable therapeutic nanoplatforms.
ACTA BIOMATERIALIA
(2023)
Article
Polymer Science
Ming -Yen Shen, Yu-Hsin Chen, Nien-Tzu Yeh, Tzu-Hao Wang, Wen-Hsuan Chiang
Summary: A pH and hydrogen peroxide-responsive nanoparticle system comprising melanin-like polydopamine (PDA) and PEGylated chitosan (PEG-CS) conjugates is developed for effective photothermal conversion and intracellular drug delivery in cancer treatment. The system shows well-dispersed spherical shape and colloidal stability in physiological salt concentration. The nanoparticles efficiently incorporate the chemotherapy drug doxorubicin (DOX) and exhibit robust photo-thermal effect and stability, while being significantly degraded by hydrogen peroxide.
EUROPEAN POLYMER JOURNAL
(2023)
Article
Engineering, Environmental
Amit N. Shocron, Rana Uwayid, Eric N. Guyes, Jouke E. Dykstra, Matthew E. Suss
Summary: Increasing global water stress has led to a growing interest in seawater desalination by reverse osmosis. Traditional methods of boron removal are costly and require additional filtration steps. This study explores a membrane- and chemical-free electrochemical technology, capacitive deionization, for boron removal. By reversing the polarity of the applied voltage during discharge, boron electrosorption is significantly enhanced, offering a promising energy consumption of 0.2 kW⋅h/m³ and efficient boron removal in a single pass.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Engineering, Environmental
Sai Kiran Hota, Gerardo Diaz
Summary: The study investigates the potential use of carbon-based biochar as a low-cost solar absorber to enhance water evaporation rates, with promising results for application in low-cost solar stills.
ENVIRONMENTAL ENGINEERING SCIENCE
(2021)
Article
Chemistry, Inorganic & Nuclear
Yuki Kadoya, Machi Hata, Yoshiki Tanaka, Atsuhiro Hirohata, Yutaka Hitomi, Masahito Kodera
Summary: A series of new dicopper complexes of a p-cresol-2,6-bis(dpa) amide-tether ligand were synthesized, among which dicopper complex 2b exhibited remarkable cytotoxicity by rapidly cleaving DNA into linear form by activating H2O2 at neutral pH, as well as attacking the nucleolus and mitochondria.
INORGANIC CHEMISTRY
(2021)
Article
Food Science & Technology
Ying Wang, Liang Wang, Jin Tan, Rong Li, Zi-Tao Jiang, Shu-Hua Tang
Summary: Microencapsulation of lavender essential oil (LEO) using metal-organic frameworks based on beta-cyclodextiin and potassium cation (K-beta CD-MOFs) improved its stabilities and antioxidant activities. The inclusion rate of K-beta CD-MOFs with a core/wall ratio of 1:10 was found to be 96.67%. The results suggest the potential of K-beta CD-MOFs as carriers for essential oils in food industry applications.
POLISH JOURNAL OF FOOD AND NUTRITION SCIENCES
(2021)
Article
Chemistry, Multidisciplinary
Amandeep Singh Pannu, Suvankar Sen, Xiaodong (Tony) Wang, Robert Jones, Kostya (Ken) Ostrikov, Prashant Sonar
Summary: Organic-inorganic hybrid lead trihalide perovskites have shown promise in various optoelectronic devices. Red-emitting perovskite-based LEDs have been less developed compared to green and blue ones. This study utilizes red-emitting 2D perovskites and carbon dots to create a stable composite material for red-emitting LEDs with improved performance.
Article
Nanoscience & Nanotechnology
Negar Zebardastan, Jonathan Bradford, Josh Lipton-Duffin, Jennifer MacLeod, Kostya (Ken) Ostrikov, Massimo Tomellini, Nunzio Motta
Summary: Face-to-face annealing is an effective method for obtaining epitaxial graphene with precise control over size, quality, growth rate and thickness.
Article
Physics, Fluids & Plasmas
Kun Liu, Wenqiang Geng, Xiongfeng Zhou, Qingsong Duan, Zhenfeng Zheng, Kostya (Ken) Ostrikov
Summary: Two modes of the atmospheric-pressure plasma discharge, characterized by the dominant O-3 and NO (x) species, were studied using numerical and experimental methods. A global chemical kinetics model was developed to investigate the mode transition mechanisms, and it accurately described the transition. The individual and synergistic effects of discharge energy and gas temperature on species density and the relative contributions of dominant reactions were quantified under increasing discharge voltage conditions.
PLASMA SOURCES SCIENCE & TECHNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Mukesh Kumar Thakur, Golam Haider, Farjana J. Sonia, Jan Plsek, Alvaro Rodriguez, Vipin Mishra, Jaganandha Panda, Ondrej Gedeon, Martin Mergl, Oleksandr Volochanskyi, Vaclav Vales, Otakar Frank, Jana Vejpravova, Martin Kalbac
Summary: Tailoring the physicochemical properties of graphene through functionalization while addressing the issue of defect formation has been a major interest. This study introduces a two-step fluorination process to stabilize fluorinated graphene and control the induced defects. The study provides a comprehensive analysis on fluorination sites, C-F bond stability, and the utilization of fluorinated graphenic carbon in practical applications such as a field-effect phototransistor.
Article
Chemistry, Multidisciplinary
Yongtao Liu, Jiajia Zhou, Shihui Wen, Fan Wang, Hongjun Wu, Qian Chen, Chao Zuo, Dayong Jin
Summary: Multiphoton upconversion super-resolution microscopy (MPUM) is a promising imaging modality that achieves increased resolution and penetration depth through the use of nonlinear near-infrared emission light. However, high excitation power is required for emission saturation, leading to increased phototoxicity. In this study, the authors propose a simple on-chip mirror design that allows for nonlinear saturation emission under low excitation power. This method significantly decreases the excitation power and enables a lateral resolution of around 35 nm in imaging single nanoparticles on-chip. The findings offer a straightforward solution for enhancing super-resolution imaging using pre-designed on-chip devices.
Article
Biochemical Research Methods
Shuang Fu, Wei Shi, Tingdan Luo, Yingchuan He, Lulu Zhou, Jie Yang, Zhichao Yang, Jiadong Liu, Xiaotian Liu, Zhiyong Guo, Chengyu Yang, Chao Liu, Zhen-li Huang, Jonas Ries, Mingjie Zhang, Peng Xi, Dayong Jin, Yiming Li
Summary: We propose a deep-learning method for precise localization of spatially variant point emitters, covering the full chip of a modern sCMOS camera. By using a graphic processing unit-based vectorial point spread function fitter, we accurately model the spatially variant PSF of a high numerical aperture objective in the entire field of view. Combined with deformable mirror-based optimal PSF engineering, we demonstrate high-accuracy three-dimensional single-molecule localization microscopy over a large volume, enabling imaging of mitochondria and nuclear pore complexes in entire cells without hardware scanning, with a 100-fold increase in throughput compared to existing techniques.
Article
Chemistry, Multidisciplinary
Haotian Gao, Guoli Wang, Zhongzheng Huang, Lanlan Nie, Dawei Liu, Xinpei Lu, Guangyuan He, Kostya Ken Ostrikov
Summary: Nitrogen fixation is a crucial process for various biological and industrial processes, but it is also a major source of carbon emissions globally. In this study, a novel approach using plasma-activated mist (PAM) is proposed for efficient and sustainable nitrogen fixation. The PAM system generates nitrogen-fixation species through the reaction of air plasma and water mist, and the liquid-phase nitrogen fixation product is dominated by NO3-. This system is applied to deliver nitrogen-based nutrients directly to plant roots using an aeroponic system, leading to significant improvements in plant growth.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2023)
Article
Chemistry, Analytical
Gungun Lin, Jawairia Umar Khan, Sareh Zhand, Yuan Liu, Dayong Jin
Summary: Researchers have developed a modular hydrogel membrane carrier with composite DNAzymes for rapid and highly sensitive detection of pathogenic bacteria gene target analytes. By incorporating composite DNAzymes into a polymer network, the researchers were able to release the DNAzymes to cleave RNA reporter probes and generate fluorescence, achieving quantitative assay performance. The work represents a significant advancement in the development of a versatile pathogenic bacteria testing platform. Overall, the importance of this research is 9 out of 10.
ANALYTICAL CHEMISTRY
(2023)
Correction
Chemistry, Analytical
Sareh Zhand, Ying Zhu, Hojjatollah Nazari, Mohammad Sadraeian, Majid Ebrahimi Warkiani, Dayong Jin
ANALYTICAL CHEMISTRY
(2023)
Article
Optics
Shui-Jing Tang, Mingjie Zhang, Jialve Sun, Jia-Wei Meng, Xiao Xiong, Qihuang Gong, Dayong Jin, Qi-Fan Yang, Yun-Feng Xiao
Summary: Researchers demonstrate real-time measurement of natural vibrations of single mesoscopic particles using photoacoustic excitation and acoustic coupling to an optical microresonator for readout. This technology extends the reach of vibrational spectroscopy and is applied for biomechanical fingerprinting of microorganisms at the single-cell level.
Article
Multidisciplinary Sciences
Chao Mi, Xun Zhang, Chengyu Yang, Jianqun Wu, Xinxin Chen, Chenguang Ma, Sitong Wu, Zhichao Yang, Pengzhen Qiao, Yang Liu, Weijie Wu, Zhiyong Guo, Jiayan Liao, Jiajia Zhou, Ming Guan, Chao Liang, Chao Liu, Dayong Jin
Summary: Researchers have developed a high-resolution near-infrared-II (NIR-II) imaging method for non-invasive diagnosis of skeletal disorders. By using lanthanide-doped nanocrystals, they were able to passively target the bone marrow and achieve effective bone imaging for over two months. The NIR-II imaging technique showed comparable results to X-ray imaging and could also diagnose early onset inflammation in rheumatoid arthritis.
NATURE COMMUNICATIONS
(2023)
Article
Chemistry, Multidisciplinary
Hsiuan Ling Ho, Jung Yen Yang, Chun Hung Lin, Jiann Shieh, Yu Fang Huang, Yi Hong Ho, Tsung Shine Ko, Chiung Chih Hsu, Kostya (Ken) Ostrikov
Summary: The development of reliable and cost-effective molecular detection at the attomolar level on analyte-immobilizing surfaces without lithographic patterning is a challenge in chemical sensing. This study presents a novel approach using plasma etching to produce custom-designed adhesive superhydrophobic silicon nanograss surfaces. These surfaces enable effective immobilization of Ag nanoparticles and R6G target molecules, providing a reliable Raman scattering platform for detecting trace analytes. The study also introduces a plasma-enabled approach for precise interface nanostructuring, potentially leading to unprecedented capabilities in molecular-level sensing technologies.
ADVANCED MATERIALS INTERFACES
(2023)
Article
Chemistry, Analytical
Gungun Lin, Jawairia Umar Khan, Sareh Zhand, Yuan Liu, Dayong Jin
Summary: This study presents a modular hydrogel membrane carrier incorporated with composite DNAzymes for rapid and highly sensitive detection of pathogenic bacteria gene targets. The composite DNAzymes are incorporated into polyethylene glycol diacrylate polymer networks, allowing for the cleavage of RNA substrate components to generate fluorescence. By modulating the morphology, composition, and microporous structures of the DNAzyme carriers, quantitative assay performance is achieved. This work represents an important advancement in the development of a generic, isothermal, and protein enzyme-free pathogenic bacteria testing platform technology.
ANALYTICAL CHEMISTRY
(2023)
Article
Engineering, Biomedical
Fu Zou, Yuanhua Liu, Zelyu Chen, Zhanghao Karl, Dayong Jin
Summary: This paper introduces a lightweight network FRUNet based on U-Net, which combines the advantages of Fourier Channel Attention (FCA Block) and Residual unit to improve image segmentation accuracy. FCA Block automatically assigns the weight of learned frequency information to the spatial domain, paying more attention to the precise high-frequency information of diverse biomedical images. The combination of FCA and U-Net is studied, with the skip connection of U-Net fusing encoder information with the decoder. Extensive experimental results show that FRUNet outperforms other advanced medical image segmentation methods in terms of network parameters and accuracy, particularly excelling in pathological section segmentation of nuclei and glands.
IEEE JOURNAL OF TRANSLATIONAL ENGINEERING IN HEALTH AND MEDICINE
(2023)
Article
Chemistry, Multidisciplinary
Zayakhuu Gerelkhuu, Haribalan Perumalsamy, Mahnaz Maddahfar, Dayong Jin, Jaewoo Song, Tae Hyun Yoon
Summary: In order to promote the use of lanthanide-doped upconversion nanoparticles (UCNPs) in various biomedical applications, it is important to assess their toxicity comprehensively, including their cellular association and interactions with human immune cells. Recent advancements in high-throughput single-cell technologies have enabled us to gain a better understanding of the complex interactions between nanoparticles and human immune cells. In this study, we used a single-cell based mass cytometry technique to investigate the heterogeneous interactions of Yb3+/Er3+-doped NaYF4 UCNPs with human peripheral blood mononuclear cells (hPBMCs). The study demonstrated a new innovative approach to understanding the heterogeneous interactions of conventional nanomaterials with complex human immune systems, which will facilitate the safe implementation of nanomaterials in biomedical applications.
ENVIRONMENTAL SCIENCE-NANO
(2023)
