Lipid-based and protein-based interactions synergize transmembrane signaling stimulated by antigen clustering of IgE receptors

Imaging FCS Delineates Subtle Heterogeneity in Plasma Membranes of Resting Mast Cells

(2020) Nirmalya Bag et al.   MOLECULAR BIOLOGY OF THE CELL

Plasma membranes are asymmetric in lipid unsaturation, packing and protein shape

(2020) J. H. Lorent et al.   Nature Chemical Biology

High-speed single-molecule imaging reveals signal transduction by induced transbilayer raft phases

(2020) Ikuko Koyama-Honda et al.   JOURNAL OF CELL BIOLOGY

How does T cell receptor clustering impact on signal transduction?

(2019) Jesse Goyette et al.   JOURNAL OF CELL SCIENCE

A lipid-based partitioning mechanism for selective incorporation of proteins into membranes of HIV particles

(2019) Prabuddha Sengupta et al.   NATURE CELL BIOLOGY

The combined hydrodynamic and thermodynamic effects of immobilized proteins on the diffusion of mobile transmembrane proteins

(2019) Rohit R. Singh et al.   JOURNAL OF FLUID MECHANICS

Synergistic factors control kinase-phosphatase organization in B cells engaged with supported bilayers

(2019) Marcos Francisco Núñez et al.   MOLECULAR BIOLOGY OF THE CELL

Computation of a Theoretical Membrane Phase Diagram and the Role of Phase in Lipid-Raft-Mediated Protein Organization

(2018) Eshan D. Mitra et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Short chain ceramides disrupt immunoreceptor signaling by inhibiting segregation of Lo from Ld Plasma membrane components

(2018) David Holowka et al.   Biology Open

“Rafts”: A nickname for putative transient nanodomains

(2018) Félix M. Goñi   CHEMISTRY AND PHYSICS OF LIPIDS

Raft-based sphingomyelin interactions revealed by new fluorescent sphingomyelin analogs

(2017) Masanao Kinoshita et al.   JOURNAL OF CELL BIOLOGY

The FcεRI signaling cascade and integrin trafficking converge at patterned ligand surfaces

(2017) Devin L. Wakefield et al.   MOLECULAR BIOLOGY OF THE CELL

The mystery of membrane organization: composition, regulation and roles of lipid rafts

(2017) Erdinc Sezgin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Localizing order to boost signaling

(2017) Štefan Bálint et al.   eLife

Protein sorting by lipid phase-like domains supports emergent signaling function in B lymphocyte plasma membranes

(2017) Matthew B Stone et al.   eLife

Roles for lipid heterogeneity in immunoreceptor signaling

(2016) David Holowka et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Functional nanoscale coupling of Lyn kinase with IgE-FcεRI is restricted by the actin cytoskeleton in early antigen-stimulated signaling

(2016) Sarah A. Shelby et al.   MOLECULAR BIOLOGY OF THE CELL

Phase separation of signaling molecules promotes T cell receptor signal transduction

(2016) Xiaolei Su et al.   SCIENCE

Plasma Membrane Organization of Epidermal Growth Factor Receptor in Resting and Ligand-Bound States

(2015) Nirmalya Bag et al.   BIOPHYSICAL JOURNAL

Nanodomains in early and later phases of FcɛRI signalling

(2015) David Holowka et al.   Essays in Biochemistry

Lipid–protein interactions

(2015) Anthony G. Lee   BIOCHEMICAL SOCIETY TRANSACTIONS

Lateral diffusion in a discrete fluid membrane with immobile particles

(2014) Ziya Kalay et al.   PHYSICAL REVIEW E

Distinct Stages of Stimulated FcεRI Receptor Clustering and Immobilization Are Identified through Superresolution Imaging

(2013) Sarah A. Shelby et al.   BIOPHYSICAL JOURNAL

Functions of the Lyn tyrosine kinase in health and disease

(2012) Evan Ingley   Cell Communication and Signaling

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Critical Casimir Forces in Cellular Membranes

(2012) Benjamin B. Machta et al.   PHYSICAL REVIEW LETTERS

Correlation Functions Quantify Super-Resolution Images and Estimate Apparent Clustering Due to Over-Counting

(2012) Sarah L. Veatch et al.   PLoS One

Measurement of Lipid Nanodomain (Raft) Formation and Size in Sphingomyelin/POPC/Cholesterol Vesicles Shows TX-100 and Transmembrane Helices Increase Domain Size by Coalescing Preexisting Nanodomains But Do Not Induce Domain Formation

(2011) Priyadarshini Pathak et al.   BIOPHYSICAL JOURNAL

Probing protein heterogeneity in the plasma membrane using PALM and pair correlation analysis

(2011) Prabuddha Sengupta et al.   NATURE METHODS

In-Plane Dynamics of Membranes with Immobile Inclusions

(2011) Naomi Oppenheimer et al.   PHYSICAL REVIEW LETTERS

What precedes the initial tyrosine phosphorylation of the high affinity IgE receptor in antigen-activated mast cell?

(2010) Viktor Bugajev et al.   FEBS LETTERS

Accumulation of raft lipids in T-cell plasma membrane domains engaged in TCR signalling

(2009) Tobias Zech et al.   EMBO JOURNAL

Small, Mobile FcɛRI Receptor Aggregates Are Signaling Competent

(2009) Nicholas L. Andrews et al.   IMMUNITY

Roles for SH2 and SH3 domains in Lyn kinase association with activated FcεRI in RBL mast cells revealed by patterned surface analysis

(2009) Stephanie Hammond et al.   JOURNAL OF STRUCTURAL BIOLOGY

Have we become overly reliant on lipid rafts? Talking Point on the involvement of lipid rafts in T-cell activation

(2008) Anne K Kenworthy   EMBO REPORTS

Actin restricts FcɛRI diffusion and facilitates antigen-induced receptor immobilization

(2008) Nicholas L. Andrews et al.   NATURE CELL BIOLOGY

Focal adhesion proteins connect IgE receptors to the cytoskeleton as revealed by micropatterned ligand arrays

(2008) A. J. Torres et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural determinants for partitioning of lipids and proteins between coexisting fluid phases in giant plasma membrane vesicles

(2007) Prabuddha Sengupta et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Src family kinases: Regulation of their activities, levels and identification of new pathways

(2007) Evan Ingley   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS