SARS-CoV-2 uses major endothelial integrin αvβ3 to cause vascular dysregulation in-vitro during COVID-19

Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study

(2020) Nanshan Chen et al.   LANCET

Autopsy Findings and Venous Thromboembolism in Patients With COVID-19

(2020) Dominic Wichmann et al.   ANNALS OF INTERNAL MEDICINE

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

SARS-CoV-2 infection of the liver directly contributes to hepatic impairment in patients with COVID-19

(2020) Yijin Wang et al.   JOURNAL OF HEPATOLOGY

Venous thromboembolism in COVID-19 patients

(2020) Angelo Porfidia et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Trials of anti-tumour necrosis factor therapy for COVID-19 are urgently needed

(2020) Marc Feldmann et al.   LANCET

Endothelial cell infection and endotheliitis in COVID-19

(2020) Zsuzsanna Varga et al.   LANCET

Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study

(2020) Fei Zhou et al.   LANCET

Large-Vessel Stroke as a Presenting Feature of Covid-19 in the Young

(2020) Thomas J. Oxley et al.   NEW ENGLAND JOURNAL OF MEDICINE

In situ detection of SARS-CoV-2 in lungs and airways of patients with COVID-19

(2020) Inga-Marie Schaefer et al.   MODERN PATHOLOGY

The protein expression profile of ACE2 in human tissues

(2020) Feria Hikmet et al.   Molecular Systems Biology

Incidence of thrombotic complications in critically ill ICU patients with COVID-19

(2020) F.A. Klok et al.   THROMBOSIS RESEARCH

New Strategy for COVID-19: An Evolutionary Role for RGD Motif in SARS-CoV-2 and Potential Inhibitors for Virus Infection

(2020) Shijia Yan et al.   Frontiers in Pharmacology

SARS-CoV-2 another kind of liver aggressor, how does it do that?

(2020) Sonia A. Lozano-Sepulveda et al.   Annals of Hepatology

A new perspective in sepsis treatment: could RGD-dependent integrins be novel targets?

(2020) Danielle Nader et al.   DRUG DISCOVERY TODAY

COVID-19 pulmonary pathology: a multi-institutional autopsy cohort from Italy and New York City

(2020) Alain C. Borczuk et al.   MODERN PATHOLOGY

Inhibition of Vascular Endothelial Cell Leak Following Escherichia coli Attachment in an Experimental Model of Sepsis

(2018) Tony M. McHale et al.   CRITICAL CARE MEDICINE

Synergistic Effect of TNF-α and Dengue Virus Infection on Adhesion Molecule Reorganization in Human Endothelial Cells

(2017) Sivaporn Inyoo et al.   JAPANESE JOURNAL OF INFECTIOUS DISEASES

A Comprehensive Evaluation of the Activity and Selectivity Profile of Ligands for RGD-binding Integrins

(2017) Tobias G. Kapp et al.   Scientific Reports

Inhibition of major integrin αVβ3reducesStaphylococcus aureusattachment to sheared human endothelial cells

(2016) C. J. McDonnell et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Arginine side chain interactions and the role of arginine as a gating charge carrier in voltage sensitive ion channels

(2016) Craig T. Armstrong et al.   Scientific Reports

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

A Study on the Effect of Surface Lysine to Arginine Mutagenesis on Protein Stability and Structure Using Green Fluorescent Protein

(2012) Sriram Sokalingam et al.   PLoS One

Phosphorylation of VE-cadherin is modulated by haemodynamic forces and contributes to the regulation of vascular permeability in vivo

(2012) Fabrizio Orsenigo et al.   Nature Communications

Absence of Integrin αvβ3 Enhances Vascular Leak in Mice by Inhibiting Endothelial Cortical Actin Formation

(2011) George Su et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Tumor necrosis factor alpha increases epithelial barrier permeability by disrupting tight junctions in Caco-2 cells

(2010) W. Cui et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH