Clinical trials in children

Parents’ Agendas in Paediatric Clinical Trial Recruitment Are Different from Researchers’ and Often Remain Unvoiced: A Qualitative Study

(2013) Kerry Woolfall et al.   PLoS One

Population survival from childhood cancer in Britain during 1978-2005 by eras of entry to clinical trials

(2012) C. A. Stiller et al.   ANNALS OF ONCOLOGY

StaR Child Health: Developing Evidence-Based Guidance for the Design, Conduct, and Reporting of Pediatric Trials

(2012) Lisa Hartling et al.   PEDIATRICS

Pediatric Versus Adult Drug Trials for Conditions With High Pediatric Disease Burden

(2012) F. T. Bourgeois et al.   PEDIATRICS

Standard 1: Consent and Recruitment

(2012) Patrina H. Y. Caldwell et al.   PEDIATRICS

Networking in paediatrics: the example of the Paediatric Rheumatology International Trials Organisation (PRINTO)

(2011) Nicolino Ruperto et al.   ARCHIVES OF DISEASE IN CHILDHOOD

Modelling and simulation as research tools in paediatric drug development

(2011) Francesco Bellanti et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

The status of paediatric medicines initiatives around the world—what has happened and what has not?

(2011) Kalle Hoppu et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

The ethics of paediatric research

(2011) Merle Spriggs et al.   JOURNAL OF PAEDIATRICS AND CHILD HEALTH

Pediatric Drug-Trial Recruitment: Enticement Without Coercion

(2011) C. L. Tishler et al.   PEDIATRICS

The development of medicines for children

(2011) Francesca Rocchi et al.   PHARMACOLOGICAL RESEARCH

The Quality of Registration of Clinical Trials

(2011) Roderik F. Viergever et al.   PLoS One

What parents think about being approached about children’s trials, how this differs from what practitioners expect, and what this tells us about enhancing recruitment

(2011) Bridget Young et al.   Trials

Innovative clinical trial design for pediatric therapeutics

(2011) Matthew M Laughon et al.   Expert Review of Clinical Pharmacology

Low quality of reporting adverse drug reactions in paediatric randomised controlled trials

(2010) T. W. de Vries et al.   ARCHIVES OF DISEASE IN CHILDHOOD

A systematic review of paediatric randomised controlled drug trials published in 2007

(2010) K. N. B. N. Aripin et al.   ARCHIVES OF DISEASE IN CHILDHOOD

Lessons from the Salk Polio Vaccine: Methods for and Risks of Rapid Translation

(2010) Justin E. Juskewitch B.A. et al.   CTS-Clinical and Translational Science

Randomized Clinical Trials in Children - Ethical and Methodological Issues

(2010) A.D. Henschel et al.   CURRENT PHARMACEUTICAL DESIGN

Clinical research in newborn infants: difficulties and specificity

(2010) Isabelle Ligi et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Comparative Effectiveness of Medical Interventions in Adults Versus Children

(2010) Despina G. Contopoulos-Ioannidis et al.   JOURNAL OF PEDIATRICS

Guidelines for the Ethical Conduct of Studies to Evaluate Drugs in Pediatric Populations

(2010) R. E. Shaddy et al.   PEDIATRICS

Controlled Trials in Children: Quantity, Methodological Quality and Descriptive Characteristics of Pediatric Controlled Trials Published 1948-2006

(2010) Denise Thomson et al.   PLoS One

Published Pediatric Randomized Drug Trials in Developing Countries, 1996–2002

(2010) Khairun N.B. Nor Aripin et al.   PEDIATRIC DRUGS

Strategies for Increasing Recruitment to Randomised Controlled Trials: Systematic Review

(2010) Patrina H. Y. Caldwell et al.   PLOS MEDICINE

Registration of trials in children: update of current international initiatives

(2009) C. Pandolfini et al.   ARCHIVES OF DISEASE IN CHILDHOOD

Ethical issues of clinical trials in children: a European perspective

(2009) H Sammons   ARCHIVES OF DISEASE IN CHILDHOOD

How do parents experience being asked to enter a child in a randomised controlled trial?

(2009) Valerie Shilling et al.   BMC Medical Ethics

Can we get the necessary clinical trials in children and avoid the unnecessary ones?

(2009) Kalle Hoppu   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Respiratory medicines for children: current evidence, unlicensed use and research priorities

(2009) A. R. Smyth et al.   EUROPEAN RESPIRATORY JOURNAL

Just a Spoonful of Sugar: Drug Safety for Pediatric Populations

(2009) Barbara A. Noah   JOURNAL OF LAW MEDICINE & ETHICS

StaR Child Health: an initiative for RCTs in children

(2009) Terry P Klassen et al.   LANCET

Avoidable waste in the production and reporting of research evidence

(2009) Iain Chalmers et al.   LANCET

Ethics and medical research in children

(2009) ANDREW J. DAVIDSON et al.   PEDIATRIC ANESTHESIA

Safety in paediatric clinical trials – a 7-year review

(2008) HM Sammons et al.   ACTA PAEDIATRICA

REPORTING OF INFORMED CONSENT, STANDARD OF CARE AND POST-TRIAL OBLIGATIONS IN GLOBAL RANDOMIZED INTERVENTION TRIALS: A SYSTEMATIC SURVEY OF REGISTERED TRIALS

(2008) EMMA R.M. COHEN et al.   Developing World Bioethics

Challenges for drug studies in children: CYP3A phenotyping as example

(2008) Saskia N. de Wildt et al.   DRUG DISCOVERY TODAY

Bitter medicine. New regulations aim to address the dearth of clinical safety trials for drugs used in children

(2008) Mark Greener   EMBO REPORTS

Clinical trials for children with cancer in Europe – Still a long way from harmonisation: A report from SIOP Europe

(2008) K. Pritchard-Jones   EUROPEAN JOURNAL OF CANCER

Good Clinical Practice and the Conduct of Clinical Studies in Pediatric Oncology

(2008) Susan Devine et al.   PEDIATRIC CLINICS OF NORTH AMERICA

Child Versus Adult Research: The Gap in High-Quality Study Design

(2008) C. Martinez-Castaldi et al.   PEDIATRICS

Pediatric developmental therapies: Interesting new drugs now in early-stage clinical trials

(2008) Margaret E. Macy et al.   Current Oncology Reports

A Systematic Review of Studies That Aim to Determine Which Outcomes to Measure in Clinical Trials in Children

(2008) Ian Sinha et al.   PLOS MEDICINE

Children Are Not Just Small Adults: The Urgent Need for High-Quality Trial Evidence in Children

(2008) Terry P Klassen et al.   PLOS MEDICINE