Investigating autism associated genes in C. elegans reveals candidates with a role in social behaviour

A Caenorhabditis elegans Model for Integrating the Functions of Neuropsychiatric Risk Genes Identifies Components Required for Normal Dendritic Morphology

(2020) Cristina Aguirre-Chen et al.   G3-Genes Genomes Genetics

Sensory Abnormalities in Autism Spectrum Disorders: A Focus on the Tactile Domain, From Genetic Mouse Models to the Clinic

(2020) Luigi Balasco et al.   Frontiers in Psychiatry

Homeostatic plasticity fails at the intersection of autism-gene mutations and a novel class of common genetic modifiers

(2020) Özgür Genç et al.   eLife

Complex Interactions between Genes and Social Environment Cause Phenotypes Associated with Autism Spectrum Disorders in Mice

(2020) Monika Sledziowska et al.   eNeuro

Understanding intellectual disability and autism spectrum disorders from common mouse models: synapses to behaviour

(2019) Vijaya Verma et al.   Open Biology

Getting to the Cores of Autism

(2019) Lilia M. Iakoucheva et al.   CELL

The expanding spectrum of neurological disorders of phosphoinositide metabolism

(2019) Jonathan R. Volpatti et al.   Disease Models & Mechanisms

Autism Spectrum Disorder-Related Syndromes: Modeling with Drosophila and Rodents

(2019) Ibuki Ueoka et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Genetic Causes and Modifiers of Autism Spectrum Disorder

(2019) Lauren Rylaarsdam et al.   Frontiers in Cellular Neuroscience

Phosphoinositides: Regulators of Nervous System Function in Health and Disease

(2019) Padinjat Raghu et al.   Frontiers in Molecular Neuroscience

An autism-causing calcium channel variant functions with selective autophagy to alter axon targeting and behavior

(2019) Tyler Buddell et al.   PLoS Genetics

Disrupted circuits in mouse models of autism spectrum disorder and intellectual disability

(2018) Carla EM Golden et al.   CURRENT OPINION IN NEUROBIOLOGY

Worms on the spectrum - C. elegans models in autism research

(2018) Kathrin Schmeisser et al.   EXPERIMENTAL NEUROLOGY

Multimodal sensory processing in Caenorhabditis elegans

(2018) Athanasios Metaxakis et al.   Open Biology

A Caenorhabditis elegans protein with a PRDM9-like SET domain localizes to chromatin-associated foci and promotes spermatocyte gene expression, sperm production and fertility

(2018) Christoph G. Engert et al.   PLoS Genetics

SET-9 and SET-26 are H3K4me3 readers and play critical roles in germline development and longevity

(2018) Wenke Wang et al.   eLife

Neurexin directs partner-specific synaptic connectivity in C. elegans

(2018) Alison Philbrook et al.   eLife

Synaptopathology Involved in Autism Spectrum Disorder

(2018) Shiqi Guang et al.   Frontiers in Cellular Neuroscience

A rapid chemical-genetic screen utilizing impaired movement phenotypes in C. elegans : Input into genetics of neurodevelopmental disorders

(2017) Kathrin Schmeisser et al.   EXPERIMENTAL NEUROLOGY

ASD and schizophrenia show distinct developmental profiles in common genetic overlap with population-based social communication difficulties

(2017) B St Pourcain et al.   MOLECULAR PSYCHIATRY

Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders

(2017) Daniel J Weiner et al.   NATURE GENETICS

Altered responses to social chemosignals in autism spectrum disorder

(2017) Yaara Endevelt-Shapira et al.   NATURE NEUROSCIENCE

Retrograde Synaptic Inhibition Is Mediated by α-Neurexin Binding to the α2δ Subunits of N-Type Calcium Channels

(2017) Xia-Jing Tong et al.   NEURON

The beneficial effects of dietary restriction on learning are distinct from its effects on longevity and mediated by depletion of a neuroinhibitory metabolite

(2017) Mihir Vohra et al.   PLOS BIOLOGY

The homeodomain-interacting protein kinase HPK-1 preserves protein homeostasis and longevity through master regulatory control of the HSF-1 chaperone network and TORC1-restricted autophagy in Caenorhabditis elegans

(2017) Ritika Das et al.   PLoS Genetics

An oxytocin-dependent social interaction between larvae and adult C. elegans

(2017) Euan Scott et al.   Scientific Reports

Neuronal mechanisms and circuits underlying repetitive behaviors in mouse models of autism spectrum disorder

(2016) Hyopil Kim et al.   Behavioral and Brain Functions

Multiple excitatory and inhibitory neural signals converge to fine-tune Caenorhabditis elegans feeding to food availability

(2016) Nicolas Dallière et al.   FASEB JOURNAL

Neurobiology of social behavior abnormalities in autism and Williams syndrome

(2016) Boaz Barak et al.   NATURE NEUROSCIENCE

A cellular and regulatory map of the GABAergic nervous system of C. elegans

(2016) Marie Gendrel et al.   eLife

Kynurenic Acid Is a Nutritional Cue that Enables Behavioral Plasticity

(2015) George A. Lemieux et al.   CELL

Trimethylation of Lys36 on H3 restricts gene expression change during aging and impacts life span

(2015) Mintie Pu et al.   GENES & DEVELOPMENT

Genetics and genomics of autism spectrum disorder: embracing complexity

(2015) Silvia De Rubeis et al.   HUMAN MOLECULAR GENETICS

Repression of the Heat Shock Response Is a Programmed Event at the Onset of Reproduction

(2015) Johnathan Labbadia et al.   MOLECULAR CELL

From the genetic architecture to synaptic plasticity in autism spectrum disorder

(2015) Thomas Bourgeron   NATURE REVIEWS NEUROSCIENCE

MADD-4/Punctin and Neurexin Organize C. elegans GABAergic Postsynapses through Neuroligin

(2015) Géraldine S. Maro et al.   NEURON

Genes, circuits, and precision therapies for autism and related neurodevelopmental disorders

(2015) M. Sahin et al.   SCIENCE

Distinct roles of the RasGAP family proteins in C. elegans associative learning and memory

(2015) M. Dávid Gyurkó et al.   Scientific Reports

Multisensory Temporal Integration in Autism Spectrum Disorders

(2014) Ryan A. Stevenson et al.   JOURNAL OF NEUROSCIENCE

Synaptic, transcriptional and chromatin genes disrupted in autism

(2014) Silvia De Rubeis et al.   NATURE

Sequential histone-modifying activities determine the robustness of transdifferentiation

(2014) S. Zuryn et al.   SCIENCE

A de novo convergence of autism genetics and molecular neuroscience

(2014) Niklas Krumm et al.   TRENDS IN NEUROSCIENCES

Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism

(2014) Roser Corominas et al.   Nature Communications

Neurexin Dysfunction in Adult Neurons Results in Autistic-like Behavior in Mice

(2014) Luis G. Rabaneda et al.   Cell Reports

A Histone Methylation Network Regulates Transgenerational Epigenetic Memory in C. elegans

(2014) Eric L. Greer et al.   Cell Reports

The Genetic Landscapes of Autism Spectrum Disorders

(2013) Guillaume Huguet et al.   Annual Review of Genomics and Human Genetics

Human alpha- and beta-NRXN1 isoforms rescue behavioral impairments ofCaenorhabditis elegansneurexin-deficient mutants

(2013) F. Calahorro et al.   GENES BRAIN AND BEHAVIOR

Shank mutant mice as an animal model of autism

(2013) J. Yoo et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The contactin RIG-6 mediates neuronal and non-neuronal cell migration in Caenorhabditis elegans

(2012) Markella Katidou et al.   DEVELOPMENTAL BIOLOGY

Depletion ofmboa-7, an enzyme that incorporates polyunsaturated fatty acids into phosphatidylinositol (PI), impairs PI 3-phosphate signaling inCaenorhabditis elegans

(2012) Hyeon-Cheol Lee et al.   GENES TO CELLS

An Evolutionarily Conserved Innate Immunity Protein Interaction Network

(2012) Lesly De Arras et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LPIAT1 regulates arachidonic acid content in phosphatidylinositol and is required for cortical lamination in mice

(2012) Hyeon-Cheol Lee et al.   MOLECULAR BIOLOGY OF THE CELL

Functional Phenotypic Rescue of Caenorhabditis elegans Neuroligin-Deficient Mutants by the Human and Rat NLGN1 Genes

(2012) Fernando Calahorro et al.   PLoS One

Dissecting a central flip-flop circuit that integrates contradictory sensory cues in C. elegans feeding regulation

(2012) Zhaoyu Li et al.   Nature Communications

Sensory Processing in Autism: A Review of Neurophysiologic Findings

(2011) ELYSA J. MARCO et al.   PEDIATRIC RESEARCH

OrthoList: A Compendium of C. elegans Genes with Human Orthologs

(2011) Daniel D. Shaye et al.   PLoS One

Genetics of autism spectrum disorders

(2011) Daniel H. Geschwind   TRENDS IN COGNITIVE SCIENCES

The Postsynaptic Organization of Synapses

(2011) M. Sheng et al.   Cold Spring Harbor Perspectives in Biology

Autism spectrum disorders

(2010) Hadeel Faras et al.   ANNALS OF SAUDI MEDICINE

Neuroligin-deficient mutants of C. elegans have sensory processing deficits and are hypersensitive to oxidative stress and mercury toxicity

(2010) J. W. Hunter et al.   Disease Models & Mechanisms

The neurexin superfamily of Caenorhabditis elegans

(2010) Liat Haklai-Topper et al.   GENE EXPRESSION PATTERNS

Reversal of Salt Preference Is Directed by the Insulin/PI3K and Gq/PKC Signaling in Caenorhabditis elegans

(2010) T. Adachi et al.   GENETICS

ANK repeat-domain of SHN-1 Is indispensable for in vivo SHN-1 function in C. elegans

(2010) Won Chan Oh et al.   MOLECULES AND CELLS

Behavioural phenotyping assays for mouse models of autism

(2010) Jill L. Silverman et al.   NATURE REVIEWS NEUROSCIENCE

Caenorhabditis elegans: a model system for systems neuroscience

(2009) Piali Sengupta et al.   CURRENT OPINION IN NEUROBIOLOGY

A Role for C. elegans Eph RTK Signaling in PTEN Regulation

(2009) Sarah Brisbin et al.   DEVELOPMENTAL CELL

A hub-and-spoke circuit drives pheromone attraction and social behaviour in C. elegans

(2009) Evan Z. Macosko et al.   NATURE

IgCAMs redundantly control axon navigation in Caenorhabditis elegans

(2009) Valentin Schwarz et al.   Neural Development

Memory in Caenorhabditis elegans Is Mediated by NMDA-Type Ionotropic Glutamate Receptors

(2008) Takashi Kano et al.   CURRENT BIOLOGY

Gustatory plasticity in C. elegans involves integration of negative cues and NaCl taste mediated by serotonin, dopamine, and glutamate

(2008) R. K. Hukema et al.   LEARNING & MEMORY

Neuroligins and neurexins link synaptic function to cognitive disease

(2008) Thomas C. Südhof   NATURE

Caenorhabditis elegans mboa-7, a Member of the MBOAT Family, Is Required for Selective Incorporation of Polyunsaturated Fatty Acids into Phosphatidylinositol

(2007) Hyeon-Cheol Lee et al.   MOLECULAR BIOLOGY OF THE CELL