Article
Critical Care Medicine
David M. Stieb, Greg J. Evans, Teresa M. To, Pascale S. J. Lakey, Manabu Shiraiwa, Marianne Hatzopoulou, Laura Minet, Jeffrey R. Brook, Richard T. Burnett, Scott A. Weichenthal
Summary: This study conducted a within-city analysis in Toronto on the COVID-19 incidence and ROS generation related to fine particulate matter. The results revealed a significant positive association between neighborhood-level ROS and COVID-19 incidence, with effect modification observed by measures of racialized group membership and socioeconomic status.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2021)
Article
Environmental Sciences
Rosane Bossle Bernardi, Ana Claudia Tedesco Zanchi, Nilsa Regina Damaceno-Rodrigues, Mariana Matera Veras, Paulo Hilario Nascimento Saldiva, Helena Maria Tannhauser Barros, Claudia Ramos Rhoden
Summary: The study found that the striatum and cortex have different reactions to air pollution, with the cortex able to avoid or reverse oxidative stress when transitioning to a non-polluted environment early in life, although some changes in the enzymatic antioxidant system may be permanent.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Review
Biochemistry & Molecular Biology
Martha Patricia Sierra-Vargas, Josaphat Miguel Montero-Vargas, Yazmin Debray-Garcia, Juan Carlos Vizuet-de-Rueda, Alejandra Loaeza-Roman, Luis M. Teran
Summary: Redox regulation plays a crucial role in controlling metabolism, with reactive oxygen and nitrogen species participating in various physiological reactions. Air pollution, particularly ambient particulate matter, containing transition metals and organic compounds, can induce inflammation, gene expression modulation, and activation of transcription factors, which contribute to the development of chronic respiratory diseases. This article provides an overview of the interaction between air pollution and redox regulation in the human body and its association with chronic respiratory diseases.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Environmental Sciences
Kexin Zhu, Richard W. Browne, Rachael Hageman Blair, Matthew R. Bonner, Mingmei Tian, Zhongzheng Niu, Furong Deng, Zeinab Farhat, Lina Mu
Summary: This study found that hydroxy metabolites derived from AA and LA are associated with air pollution and may interact with systemic inflammation in response to air pollution exposure.
ENVIRONMENTAL RESEARCH
(2021)
Article
Biochemistry & Molecular Biology
Anita Morandi, Massimiliano Corradi, Chiara Zusi, Claudia Piona, Silvia Costantini, Marco Marigliano, Claudio Maffeis
Summary: This study assessed the association between rs2364723 of NFE2L2 gene and oxidative stress in children/adolescents with T1D. The carriers of the minor genotype of rs2364723 may have increased oxidative stress, especially in case of poor glycemic control.
Article
Environmental Sciences
Sindy San Juan-Reyes, Leobardo Manuel Gomez-Olivan, Nely San Juan-Reyes, Hariz Islas-Flores, Octavio Dublan-Garcia, Jose Manuel Orozco-Hernandez, Itzayana Perez-alvarez, Alejandro Mejia-Garcia
Summary: Oxidative imbalance is a known pathophysiological mechanism in pregnant women with preeclampsia and their newborns, with similar effects seen in individuals exposed to air pollution. This study aimed to investigate the biomarkers of oxidative stress and their association with neonatal diseases in premature babies born to mothers with preeclampsia and exposed to air pollution during pregnancy. Results showed higher levels of oxidative stress markers in preeclamptic women and their newborns exposed to higher levels of air pollutants during the first and second trimesters. Neonatal diseases such as intrauterine growth restriction and necrotizing enterocolitis were significantly correlated with prooxidant agents and antioxidant enzyme activity in preeclampsia. The findings suggest increased oxidative damage in both maternal and fetal circulation in preeclamptic women exposed to air pollution, leading to worse outcomes in preterm infants.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Nicolas Visez, Mona Hamze, Klervi Vandenbossche, Florent Occelli, Patricia de Naidai, Yeny Tobon, Tomas Hajek, Marie Choel
Summary: Ozone can worsen allergy symptoms to certain pollens. The study investigated the uptake of ozone by different types of pollens and found that it varied greatly among the tested taxa. Tree pollens generally captured more ozone than herbaceous pollens, and lipids seemed to act as a protective barrier. After inhalation, pollen-transported ozone could exacerbate allergic symptoms through oxidative stress and local inflammation. The mechanism of pollen-induced oxidative stress could explain the aggravation of allergic symptoms during episodes of ozone pollution.
ENVIRONMENTAL POLLUTION
(2023)
Article
Environmental Sciences
Kin-Fai Ho, Ya-Chun Lee, Xinyi Niu, Hongmei Xu, Renjian Zhang, Jun-Ji Cao, Cheng-Yu Tsai, Ta-Chih Hsiao, Hsiao-Chi Chuang
Summary: This study investigated the impact of chemical components in PM2.5 on particle bioreactivity during haze episodes in Chinese megacities, revealing that OC and acidic ions play important roles in regulating oxidative stress and inflammation. The findings suggest that severe haze PM2.5 events deteriorate air quality and may have adverse effects on human health.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Public, Environmental & Occupational Health
Xiao Wu, Xin Cao, Jutta Lintelmann, Annette Peters, Wolfgang Koenig, Ralf Zimmermann, Alexandra Schneider, Kathrin Wolf, for the KORA-Study Group
Summary: The results of this study suggest that exposure to polycyclic aromatic hydrocarbons (PAHs) is associated with oxidative stress even in a low exposure setting. Oxidative stress markers, but not PAHs, were associated with inflammation. Individual risk factors played an important role in these processes and should be considered in future studies.
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2022)
Review
Biochemistry & Molecular Biology
Miguel Santibanez-Andrade, Ericka Marel Quezada-Maldonado, Andrea Rivera-Pineda, Yolanda I. I. Chirino, Claudia M. Garcia-Cuellar, Yesennia Sanchez-Perez
Summary: Oxidative stress in cells is caused by an imbalance between oxidant production and the antioxidant system's ability to detoxify reactive products. This stress can lead to genotoxic damage, mutation, and play a role in carcinogenesis. Particulate matter (PM) air pollution has been identified as a cancer risk factor, and evidence suggests that PM-induced oxidative stress can contribute to various events promoting carcinogenesis. This review emphasizes the importance of studying the oxidative and genotoxic mechanisms associated with PM in malignant cell transformation and calls for more accurate approaches to assess its carcinogenic potential.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Engineering, Environmental
Xiaoyan Yang, Qin Wang, Feng Han, Bin Dong, Bo Wen, Li Li, Hongjie Ruan, Shaoping Zhang, Jian Kong, Hong Zhi, Chong Wang, Jun Wang, Ming Zhang, Dongqun Xu
Summary: The study showed that air cleaner intervention can reduce early abnormal responses in the respiratory system of healthy schoolchildren under short-term PM exposure, with boys being more sensitive than girls. PM concentrations have a lag and cumulative effect on biomarkers, with lag 1 day having the greatest impact.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Arianna Dondi, Claudio Carbone, Elisa Manieri, Daniele Zama, Chiara Del Bono, Ludovica Betti, Carlotta Biagi, Marcello Lanari
Summary: Air pollutants exert damaging effects through mechanisms such as oxidative stress promotion, inflammatory response induction, and immune system deregulation. Childhood, especially prenatal age, is the most vulnerable period due to the inability to efficiently detoxify oxidative damage and higher metabolic and breathing rates. Air pollution is associated with acute disorders like asthma exacerbations and respiratory infections, as well as chronic asthma, lung function deficit and growth impairment.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Environmental Sciences
Junnan Yang, Mengyu Chu, Chen Gong, Xian Gong, Bin Han, Li Chen, Jianmei Wang, Zhipeng Bai, Yujuan Zhang
Summary: This study found an association between exposure to fine particulate matter (PM2.5) and oxidative protein damage in early pregnant women, especially in those with clinically recognized early pregnancy loss (CREPL). The results showed that PM2.5 and nitrogen dioxide (NO2) exposure were associated with increased levels of serum 3-nitrotyrosine (3-NT) and advanced oxidation protein products (AOPP). The study also identified combustion PM2.5 as the crucial component. Therefore, wearing masks may potentially help prevent PM2.5 exposure and its related oxidative protein damage.
ENVIRONMENTAL POLLUTION
(2023)
Article
Environmental Sciences
Beate Ritz, Qi Yan, Di He, Jun Wu, Douglas Walker, Karan Uppal, Dean P. Jones, Julia E. Heck
Summary: This study investigated the metabolic effects of air pollution exposure during pregnancy on neonates and found that neonates exposed to air pollution exhibit alterations in oxidative stress and inflammation pathways related to lipid metabolism.
ENVIRONMENTAL RESEARCH
(2022)
Article
Environmental Sciences
Xinhui Wu, Chiara Ciminieri, I. Sophie T. Bos, Manon E. Woest, Angela D'Ambrosi, Rene Wardenaar, Diana C. J. Spierings, Melanie Konigshoff, Martina Schmidt, Loes E. M. Kistemaker, Reinoud Gosens
Summary: Chronic obstructive pulmonary disease (COPD) is a progressive lung disease caused by environmental pollution, particularly motor vehicle emissions. Diesel exhaust particles (DEP) exposure affects the epithelial-mesenchymal signaling niche in the distal lung, impairing tissue repair. Targeting oxidative stress and the WNT/β-catenin signaling pathway may be a potential strategy for restoring tissue repair in COPD.
ENVIRONMENTAL POLLUTION
(2022)
Article
Agronomy
Anthony Digrado, Noah G. Mitchell, Christopher M. Montes, Paulina Dirvanskyte, Elizabeth A. Ainsworth
FOOD AND ENERGY SECURITY
(2020)
Article
Plant Sciences
Shuai Li, Christopher A. Moller, Noah G. Mitchell, DoKyoung Lee, Elizabeth A. Ainsworth
Summary: The research found that bioenergy sorghum is tolerant to elevated tropospheric ozone concentration and could be used to enhance biomass productivity in regions with ozone pollution.
PLANT CELL AND ENVIRONMENT
(2021)
Review
Biochemistry & Molecular Biology
Jessica M. Wedow, Elizabeth A. Ainsworth, Shuai Li
Summary: Tropospheric ozone is a harmful air pollutant to plants, and plants can both emit volatile organic compounds that contribute to ozone formation and take in ozone through dry deposition. The biochemical fate of ozone within leaves is not fully understood, but new tracking techniques show promise in revealing this process.
TRENDS IN BIOCHEMICAL SCIENCES
(2021)
Article
Environmental Sciences
Hyungsuk Kimm, Kaiyu Guan, Chongya Jiang, Guofang Miao, Genghong Wu, Andrew E. Suyker, Elizabeth A. Ainsworth, Carl J. Bernacchi, Christopher M. Montes, Joseph A. Berry, Xi Yang, Christian Frankenberg, Min Chen, Philipp Kohler
Summary: This study evaluates the potential of using SIF-derived physiological signals to quantify crop responses to environmental stresses at different spatial scales within the U.S. Corn Belt. The findings suggest that physiological variations contribute significantly to SIF signals, and this physiological information can reflect crop responses to stresses with greater sensitivity and spatial scalability compared to SIF alone.
ENVIRONMENTAL RESEARCH LETTERS
(2021)
Article
Biodiversity Conservation
Shuai Li, Christopher A. Moller, Noah G. Mitchell, DoKyoung Lee, Erik J. Sacks, Elizabeth A. Ainsworth
Summary: There is significant variation in O-3 sensitivity among C-4 species, with stomatal conductance and leaf structure playing important roles in determining this variation.
GLOBAL CHANGE BIOLOGY
(2022)
Article
Plant Sciences
Etsushi Kumagai, Charles H. Burroughs, Taylor L. Pederson, Christopher M. Montes, Bin Peng, Hyungsuk Kimm, Kaiyu Guan, Elizabeth A. Ainsworth, Carl J. Bernacchi
Summary: Hyperspectral reflectance can accurately measure the maximum rate of photosynthesis and maximum electron transport in soybean leaves, providing insights into the biochemical acclimation process to high temperatures.
PLANT CELL AND ENVIRONMENT
(2022)
Review
Plant Sciences
Peng Fu, Christopher M. Montes, Matthew H. Siebers, Nuria Gomez-Casanovas, Justin M. McGrath, Elizabeth A. Ainsworth, Carl J. Bernacchi
Summary: High-throughput phenotyping of photosynthesis is crucial for improving crop yield. Gas exchange techniques have revolutionized plant research but are limited by equipment and personnel availability for high-throughput phenotyping. Remote sensing techniques offer the potential to assess photosynthesis at finer spatial scales. This review outlines the interests and advances in high-throughput techniques for characterizing photosynthesis and discusses the current limitations, bottlenecks, and opportunities facing this field.
JOURNAL OF EXPERIMENTAL BOTANY
(2022)
Article
Genetics & Heredity
Christopher M. Montes, Carolyn Fox, Alvaro Sanz-Saez, Shawn P. Serbin, Etsushi Kumagai, Matheus D. Krause, Alencar Xavier, James E. Specht, William D. Beavis, Carl J. Bernacchi, Brian W. Diers, Elizabeth A. Ainsworth
Summary: Photosynthesis is a key target for improving crop production, but traditional methods for studying photosynthetic traits are slow and destructive. Researchers used leaf reflectance spectroscopy to build models for estimating photosynthetic traits and applied them to a soybean population, finding insights into the genetic architecture of photosynthetic traits and their impact on soybean yield.
Article
Plant Sciences
Shuai Li, Christopher A. Moller, Noah G. Mitchell, Duncan G. Martin, Erik J. Sacks, Sampurna Saikia, Nicholas R. Labonte, Brian S. Baldwin, Jesse Morrison, John N. Ferguson, Andrew D. B. Leakey, Elizabeth A. Ainsworth
Summary: This study investigated the trait variations of C-4 species Miscanthusx giganteus and its potential contribution to the leaf economics spectrum (LES). The results revealed that M.x giganteus genotypes displayed higher photosynthetic rates, lower stomatal conductance, and less nitrogen content compared to the global LES, indicating greater water and photosynthetic nitrogen use efficiency in C-4 species. Additionally, the study found that tetraploid genotypes of M.x giganteus exhibited thicker leaves, greater leaf mass per area, and lower leaf density than triploid genotypes, suggesting the potential impact of ploidy on LES traits.
PLANT CELL AND ENVIRONMENT
(2022)
Article
Plant Sciences
Shunsuke Adachi, Matt Stata, Duncan G. Martin, Shifeng Cheng, Hongbing Liu, Xin-Guang Zhu, Rowan F. Sage
Summary: Flaveria is an important model for understanding C-4 plant evolution. Through studying different Flaveria species, this research discovered functional clusters and identified certain characteristics that may facilitate the evolution of the full C-4 photosynthetic pathway.
Article
Plant Sciences
Charles H. Burroughs, Christopher M. Montes, Christopher A. Moller, Noah G. Mitchell, Anne Marie Michael, Bin Peng, Hyungsuk Kimm, Taylor L. Pederson, Alexander E. Lipka, Carl J. Bernacchi, Kaiyu Guan, Elizabeth A. Ainsworth
Summary: Improvements in genetics, technology, and agricultural intensification have increased soybean yields, but adverse climate conditions may hinder further progress. This study found that high temperature has a nonlinear impact on yield, with decreases observed when canopy temperature exceeds a threshold. In the US Midwest, increased temperature reduces soybean yields through reduced leaf area, fewer pods per node, smaller seeds, and decreased harvest index.
JOURNAL OF EXPERIMENTAL BOTANY
(2023)
Article
Multidisciplinary Sciences
Elise Kole Aspray, Timothy A. Mies, Jesse A. McGrath, Christopher M. Montes, Bradley Dalsing, Kannan K. Puthuval, Andrew Whetten, Jelena Herriott, Shuai Li, Carl J. Bernacchi, Evan H. DeLucia, Andrew D. B. Leakey, Stephen P. Long, Justin M. McGrath, Franco Miglietta, Donald R. Ort, Elizabeth A. Ainsworth
Summary: The Soybean Free Air Concentration Enrichment (SoyFACE) facility is the longest running open-air carbon dioxide and ozone enrichment facility in the world. It exposes crops to elevated atmospheric concentrations and provides important data for predicting future crop productivity. This study collates 20 years of data to facilitate trend analysis and crop modeling efforts.