Neuroprotective effects of salidroside on ageing hippocampal neurons and naturally ageing mice via the PI3K /Akt/ TERT pathway

Remodeling of Intracellular Ca2+ Homeostasis in Rat Hippocampal Neurons Aged In Vitro

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Investigation of endogenous malondialdehyde through fluorescent probe MDA-6 during oxidative stress

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Brain aging: A Ianus -faced player between health and neurodegeneration

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Salidroside Protection Against Oxidative Stress Injury Through the Wnt/β-Catenin Signaling Pathway in Rats with Parkinson’s Disease

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Pharmacological activities, mechanisms of action, and safety of salidroside in the central nervous system

(2018) Zhifeng Zhong et al.   Drug Design Development and Therapy

Antidepressant-like effect of salidroside and curcumin on the immunoreactivity of rats subjected to a chronic mild stress model

(2018) Liliya V. Vasileva et al.   FOOD AND CHEMICAL TOXICOLOGY

Salidroside improves the hypoxic tumor microenvironment and reverses the drug resistance of platinum drugs via HIF-1α signaling pathway

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Salidroside suppressing LPS-induced myocardial injury by inhibiting ROS-mediated PI3K/Akt/mTOR pathway in vitro and in vivo

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(2017) Jean-Philippe Coutu et al.   NEUROBIOLOGY OF AGING

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Neuroprotective effects of the catalytic subunit of telomerase: A potential therapeutic target in the central nervous system

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Decreased mTOR signalling reduces mitochondrial ROS in brain via accumulation of the telomerase protein TERT within mitochondria

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FMRP regulates an ethanol-dependent shift in GABABR function and expression with rapid antidepressant properties

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Telomerase activation as a possible mechanism of action for psychopharmacological interventions

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Cordyceptin induces apoptosis through repressing hTERT expression and inducing extranuclear export of hTERT

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The Role of Telomerase Protein TERT in Alzheimer's Disease and in Tau-Related Pathology In Vitro

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An UPLC-MS-based metabolomics investigation on the anti-fatigue effect of salidroside in mice

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Physiological geroscience: targeting function to increase healthspan and achieve optimal longevity

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Extra-telomeric Functions of Human Telomerase: Cancer, Mitochondria and Oxidative Stress

(2014) G. Saretzki   CURRENT PHARMACEUTICAL DESIGN

Protective Effects of Salidroside in the MPTP/MPP+-Induced Model of Parkinson's Disease through ROS–NO-Related Mitochondrion Pathway

(2014) Songhai Wang et al.   MOLECULAR NEUROBIOLOGY

The Hallmarks of Aging

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Oxidative stress, DNA damage, and the telomeric complex as therapeutic targets in acute neurodegeneration

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The neuroprotective role and mechanisms of TERT in neurons with oxygen–glucose deprivation

(2013) J. Li et al.   NEUROSCIENCE

Activation of Ras/PI3K/ERK Pathway Induces c-Myc Stabilization to Upregulate Argininosuccinate Synthetase, Leading to Arginine Deiminase Resistance in Melanoma Cells

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Novel telomerase-increasing compound in mouse brain delays the onset of amyotrophic lateral sclerosis

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Nuclear import of hTERT requires a bipartite nuclear localization signal and Akt-mediated phosphorylation

(2012) J. Chung et al.   JOURNAL OF CELL SCIENCE

Characterizing cognitive aging of spatial and contextual memory in animal models

(2012) Thomas C. Foster et al.   Frontiers in Aging Neuroscience

Telomere-independent functions of telomerase in nuclei, cytoplasm, and mitochondria

(2012) Ilaria Chiodi et al.   Frontiers in Oncology

Telomere shortening reduces Alzheimer’s disease amyloid pathology in mice

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Human telomerase acts as a hTR-independent reverse transcriptase in mitochondria

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Senescence-associated beta-galactosidase activity expression in aging hippocampal neurons

(2010) Yi-Qun Geng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Evaluation of salidrosidein vitroandin vivogenotoxicity

(2010) Jiangbo Zhu et al.   DRUG AND CHEMICAL TOXICOLOGY

The essence of senescence

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Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice

(2010) Mariela Jaskelioff et al.   NATURE

Telomerase Deficiency Affects Normal Brain Functions in Mice

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