Amide Formation: Choosing the Safer Carbodiimide in Combination with OxymaPure to Avoid HCN Release

Minimizing HCN in DIC/Oxyma-Mediated Amide Bond-Forming Reactions

(2020) Marion Erny et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Generation of Hydrogen Cyanide from the Reaction of Oxyma (Ethyl Cyano(hydroxyimino)acetate) and DIC (Diisopropylcarbodiimide)

(2019) Adam D. McFarland et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Choosing the Right Coupling Reagent for Peptides: A Twenty-Five-Year Journey

(2018) Fernando Albericio et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Peptide Coupling Reagents, More than a Letter Soup

(2011) Ayman El-Faham et al.   CHEMICAL REVIEWS

The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates

(2011) Stephen D. Roughley et al.   JOURNAL OF MEDICINAL CHEMISTRY

Factors Determining the Selection of Organic Reactions by Medicinal Chemists and the Use of These Reactions in Arrays (Small Focused Libraries)

(2010) Tony W. J. Cooper et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Novel Family of Onium Salts Based Upon Isonitroso Meldrum's Acid Proves Useful as Peptide Coupling Reagents

(2010) Ayman El-Faham et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

PyOxP and PyOxB: the Oxyma-based novel family of phosphonium salts

(2010) Ramon Subirós-Funosas et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Amino Acid-Protecting Groups

(2009) Albert Isidro-Llobet et al.   CHEMICAL REVIEWS

COMU: A Safer and More Effective Replacement for Benzotriazole-Based Uronium Coupling Reagents

(2009) Ayman El-Faham et al.   CHEMISTRY-A EUROPEAN JOURNAL

Oxyma: An Efficient Additive for Peptide Synthesis to Replace the Benzotriazole-Based HOBt and HOAt with a Lower Risk of Explosion[1]

(2009) Ramon Subirós-Funosas et al.   CHEMISTRY-A EUROPEAN JOURNAL

COMU: A third generation of uronium-type coupling reagents

(2009) Ayman El-Faham et al.   JOURNAL OF PEPTIDE SCIENCE