Journal
FUTURE MICROBIOLOGY
Volume 11, Issue 7, Pages 973-985Publisher
FUTURE MEDICINE LTD
DOI: 10.2217/fmb-2016-0062
Keywords
diagnosis; gold nanorods; gold nanospheres; Paracoccidioides brasiliensis; Paracoccidioides lutzii; paracoccidioidomycosis
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Paracoccidioidomycosis (PCM) is a human systemic granulomatous mycosis caused by thermodimorphic fungi from Paracoccidioides genus. The disease is prevalent in Latin America and triggers a serious clinical condition. Consequently, rapid diagnosis and treatment are crucial to prevent progression of the disease, which can result in death. Currently, there are several established methods for PCM diagnosis. However, many of these tests still present challenges in terms of cost, accessibility and efficiency. In this scenario, gold nanoparticles represent a promising alternative since they have particular optical and electronic properties, which allow its use for biomolecules detection. This review will briefly present techniques available for PCM diagnosis and the perspectives of implementation of gold nanoparticles for diagnosis of this mycosis.
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