How can we bolster the antifungal drug discovery pipeline?

Synergistic Effect of Fluconazole and Calcium Channel Blockers against Resistant Candida albicans

(2016) Shuyuan Liu et al.   PLoS One

Myconanoparticles: synthesis and their role in phytopathogens management

(2015) Mousa A. Alghuthaymi et al.   BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT

Potential of agricultural fungicides for antifungal drug discovery

(2015) Josef Jampilek   Expert Opinion on Drug Discovery

How to bolster the antifungal pipeline

(2015) D. W. Denning et al.   SCIENCE

Identification of a New Class of Antifungals Targeting the Synthesis of Fungal Sphingolipids

(2015) Visesato Mor et al.   mBio

A combination approach to treating fungal infections

(2015) Sanjib K. Shrestha et al.   Scientific Reports

A novel small molecule inhibitor of Candida albicans biofilm formation, filamentation and virulence with low potential for the development of resistance

(2015) Christopher G Pierce et al.   npj Biofilms and Microbiomes

Scaffold hopping of sampangine: Discovery of potent antifungal lead compound against Aspergillus fumigatus and Cryptococcus neoformans

(2014) Zhigan Jiang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

In pursuit of the ideal antifungal agent for Candida infections: high-throughput screening of small molecules

(2014) Sarah S.W. Wong et al.   DRUG DISCOVERY TODAY

Antifungal drug discovery: the process and outcomes

(2014) Richard Calderone et al.   Future Microbiology

Combination of fluconazole with non-antifungal agents: A promising approach to cope with resistant Candida albicans infections and insight into new antifungal agent discovery

(2014) Shuyuan Liu et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Efflux pump proteins in antifungal resistance

(2014) Rajendra Prasad et al.   Frontiers in Pharmacology

Chemical Genomics-Based Antifungal Drug Discovery: Targeting Glycosylphosphatidylinositol (GPI) Precursor Biosynthesis

(2014) Paul A. Mann et al.   ACS Infectious Diseases

Crossover fungal pathogens: The biology and pathogenesis of fungi capable of crossing kingdoms to infect plants and humans

(2013) Gregory M. Gauthier et al.   FUNGAL GENETICS AND BIOLOGY

Emerging fungal threats to animal, plant and ecosystem health

(2012) Matthew C. Fisher et al.   NATURE

Antifungal Spectrum, In Vivo Efficacy, and Structure–Activity Relationship of Ilicicolin H

(2012) Sheo B. Singh et al.   ACS Medicinal Chemistry Letters

Fifty years of drug discovery from fungi

(2011) Amal H. Aly et al.   FUNGAL DIVERSITY

Cross-species discovery of syncretic drug combinations that potentiate the antifungal fluconazole

(2011) M. Spitzer et al.   Molecular Systems Biology