Dynorphin A analogs for the treatment of chronic neuropathic pain

Modification of amphipathic non-opioid dynorphin A analogues for rat brain bradykinin receptors

(2015) Yeon Sun Lee et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Structure–activity relationships of non-opioid [des-Arg7]-dynorphin A analogues for bradykinin receptors

(2014) Yeon Sun Lee et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Putative Kappa Opioid Heteromers As Targets for Developing Analgesics Free of Adverse Effects

(2014) Morgan Le Naour et al.   JOURNAL OF MEDICINAL CHEMISTRY

Discovery of Amphipathic Dynorphin A Analogues to Inhibit the Neuroexcitatory Effects of Dynorphin A through Bradykinin Receptors in the Spinal Cord

(2014) Yeon Sun Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Minocycline prevents dynorphin-induced neurotoxicity during neuropathic pain in rats

(2014) Ewelina Rojewska et al.   NEUROPHARMACOLOGY

Bolus Intrathecal Injection of Ziconotide (Prialt®) to Evaluate the Option of Continuous Administration via an Implanted Intrathecal Drug Delivery (ITDD) System: A Pilot Study

(2012) Salma I. Mohammed et al.   NEUROMODULATION

The NMDA receptor complex as a therapeutic target in epilepsy: a review

(2011) Mehdi Ghasemi et al.   EPILEPSY & BEHAVIOR

The evidence for pharmacological treatment of neuropathic pain

(2010) Nanna Brix Finnerup et al.   PAIN

Kinase cascades and ligand-directed signaling at the kappa opioid receptor

(2010) Michael R. Bruchas et al.   PSYCHOPHARMACOLOGY

Peptide Kappa Opioid Receptor Ligands: Potential for Drug Development

(2009) Jane V. Aldrich et al.   AAPS Journal

The dynorphin/kappa opioid system as a modulator of stress-induced and pro-addictive behaviors

(2009) M.R. Bruchas et al.   BRAIN RESEARCH

kappa-Opioid receptor signaling and brain reward function

(2009) Adrie W. Bruijnzeel   BRAIN RESEARCH REVIEWS

Local peripheral opioid effects and expression of opioid genes in the spinal cord and dorsal root ganglia in neuropathic and inflammatory pain

(2009) Ilona Obara et al.   PAIN

30 years of dynorphins — New insights on their functions in neuropsychiatric diseases

(2009) Christoph Schwarzer   PHARMACOLOGY & THERAPEUTICS

Zyklophin, a systemically active selective kappa opioid receptor peptide antagonist with short duration of action

(2009) J. V. Aldrich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spinal Dynorphin and Bradykinin Receptors Maintain Inflammatory Hyperalgesia

(2008) Miaw-Chyi Luo et al.   JOURNAL OF PAIN