Inhibition of bacterial and fungal pathogens by the orphaned drug auranofin

Antifungal susceptibilities of Candida, Cryptococcus neoformans and Aspergillus fumigatus from the Asia and Western Pacific region: data from the SENTRY antifungal surveillance program (2010–2012)

(2015) Michael A Pfaller et al.   JOURNAL OF ANTIBIOTICS

Auranofin exerts broad-spectrum bactericidal activities by targeting thiol-redox homeostasis

(2015) Michael B. Harbut et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Declining Incidence of Candidemia and the Shifting Epidemiology of Candida Resistance in Two US Metropolitan Areas, 2008–2013: Results from Population-Based Surveillance

(2015) Angela Ahlquist Cleveland et al.   PLoS One

Drug repositioning: auranofin as a prospective antimicrobial agent for the treatment of severe staphylococcal infections

(2014) Maria Iris Cassetta et al.   BIOMETALS

Differential Response of Candida albicans and Candida glabrata to Oxidative and Nitrosative Stresses

(2014) Mayra Cuéllar-Cruz et al.   CURRENT MICROBIOLOGY

Clinical Management ofStaphylococcus aureusBacteremia

(2014) Thomas L. Holland et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Whole Animal Automated Platform for Drug Discovery against Multi-Drug Resistant Staphylococcus aureus

(2014) Rajmohan Rajamuthiah et al.   PLoS One

Antifungal Application of Nonantifungal Drugs

(2013) Marios Stylianou et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A Reprofiled Drug, Auranofin, Is Effective against Metronidazole-Resistant Giardia lamblia

(2013) Noa Tejman-Yarden et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

High-Throughput Screening of a Collection of Known Pharmacologically Active Small Compounds for Identification of Candida albicans Biofilm Inhibitors

(2013) Samuel A. Siles et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The thioredoxin antioxidant system

(2013) Jun Lu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Small molecules inhibit growth, viability and ergosterol biosynthesis in Candida albicans

(2013) Sandeep B Rajput et al.   SpringerPlus

Inhibition of bacterial thioredoxin reductase: an antibiotic mechanism targeting bacteria lacking glutathione

(2012) Jun Lu et al.   FASEB JOURNAL

Resistance of Asian Cryptococcus neoformans Serotype A Is Confined to Few Microsatellite Genotypes

(2012) Weihua Pan et al.   PLoS One

Gold(I) Complexes of N-Heterocyclic Carbene Ligands Containing Benzimidazole: Synthesis and Antimicrobial Activity

(2010) İlknur Özdemir et al.   MOLECULES

Inhibition of Selenium Metabolism in the Oral Pathogen Treponema denticola

(2009) S. Jackson-Rosario et al.   JOURNAL OF BACTERIOLOGY

Inhibition ofSchistosoma mansoniThioredoxin-glutathione Reductase by Auranofin

(2009) Francesco Angelucci et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Auranofin disrupts selenium metabolism in Clostridium difficile by forming a stable Au–Se adduct

(2009) Sarah Jackson-Rosario et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Platyhelminth Mitochondrial and Cytosolic Redox Homeostasis Is Controlled by a Single Thioredoxin Glutathione Reductase and Dependent on Selenium and Glutathione

(2008) Mariana Bonilla et al.   JOURNAL OF BIOLOGICAL CHEMISTRY