The role of reciprocal fusions in MLL-r acute leukemia: studying the chromosomal translocation t(4;11)

The reciprocal world of MLL fusions: A personal view

(2020) Rolf Marschalek   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Only Hematopoietic Stem and Progenitor Cells from Cord Blood Are Susceptible to Malignant Transformation by MLL-AF4 Translocations

(2020) Kathy-Ann Secker et al.   Cancers

Unravelling the cellular origin and clinical prognostic markers of infant B-cell acute lymphoblastic leukemia using genome-wide analysis

(2019) Antonio Agraz-Doblas et al.   HAEMATOLOGICA

Expression of mitochondrial genes predicts survival in pediatric acute myeloid leukemia

(2019) Anudishi Tyagi et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

The MLL recombinome of acute leukemias in 2017

(2017) C Meyer et al.   LEUKEMIA

An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues

(2017) M Ryan Corces et al.   NATURE METHODS

Instructive Role of MLL-Fusion Proteins Revealed by a Model of t(4;11) Pro-B Acute Lymphoblastic Leukemia

(2016) Shan Lin et al.   CANCER CELL

Optimized Sleeping Beauty transposons rapidly generate stable transgenic cell lines

(2015) Eric Kowarz et al.   Biotechnology Journal

The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias

(2015) Anna K Andersson et al.   NATURE GENETICS

Optimized Sleeping Beauty transposons rapidly generate stable transgenic cell lines

(2015) Eric Kowarz et al.   Biotechnology Journal

RUNX1 Is a Key Target in t(4;11) Leukemias that Contributes to Gene Activation through an AF4-MLL Complex Interaction

(2013) Adam C. Wilkinson et al.   Cell Reports

Secondary mutations in t(4;11) leukemia patients

(2012) C Prelle et al.   LEUKEMIA

The super elongation complex (SEC) family in transcriptional control

(2012) Zhuojuan Luo et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The AF4{middle dot}MLL fusion protein is capable of inducing ALL in mice without requirement of MLL{middle dot}AF4

(2010) A. Bursen et al.   BLOOD

CYCLINg through transcription: Post-translational modifications of P-TEFb regulate transcription elongation

(2010) Sungyoo Cho et al.   CELL CYCLE

The leukemogenic AF4–MLL fusion protein causes P-TEFb kinase activation and altered epigenetic signatures

(2010) A Benedikt et al.   LEUKEMIA

Circos: An information aesthetic for comparative genomics

(2009) M. Krzywinski et al.   GENOME RESEARCH

DNA copy-number abnormalities do not occur in infant ALL with t(4;11)/MLL-AF4

(2009) M Bardini et al.   LEUKEMIA