Signature morpho-electric, transcriptomic, and dendritic properties of human layer 5 neocortical pyramidal neurons

Enhancer viruses for combinatorial cell-subclass-specific labeling

(2021) Lucas T. Graybuck et al.   NEURON

Scaled, high fidelity electrophysiological, morphological, and transcriptomic cell characterization

(2021) Brian R Lee et al.   eLife

Dendritic action potentials and computation in human layer 2/3 cortical neurons

(2020) Albert Gidon et al.   SCIENCE

Transcriptomic evidence that von Economo neurons are regionally specialized extratelencephalic-projecting excitatory neurons

(2020) Rebecca D. Hodge et al.   Nature Communications

Active dendritic currents gate descending cortical outputs in perception

(2020) Naoya Takahashi et al.   NATURE NEUROSCIENCE

Classification of electrophysiological and morphological neuron types in the mouse visual cortex

(2019) Nathan W. Gouwens et al.   NATURE NEUROSCIENCE

Conserved cell types with divergent features in human versus mouse cortex

(2019) Rebecca D. Hodge et al.   NATURE

Specialized Subpopulations of Deep-Layer Pyramidal Neurons in the Neocortex: Bridging Cellular Properties to Functional Consequences

(2018) Arielle Baker et al.   JOURNAL OF NEUROSCIENCE

Cell-Type Specificity of Callosally Evoked Excitation and Feedforward Inhibition in the Prefrontal Cortex

(2018) Paul G. Anastasiades et al.   Cell Reports

Enhanced Dendritic Compartmentalization in Human Cortical Neurons

(2018) Lou Beaulieu-Laroche et al.   CELL

Shared and distinct transcriptomic cell types across neocortical areas

(2018) Bosiljka Tasic et al.   NATURE

Distinct descending motor cortex pathways and their roles in movement

(2018) Michael N. Economo et al.   NATURE

Neocortical Topology Governs the Dendritic Integrative Capacity of Layer 5 Pyramidal Neurons

(2018) Lee N. Fletcher et al.   NEURON

h-Channels Contribute to Divergent Intrinsic Membrane Properties of Supragranular Pyramidal Neurons in Human versus Mouse Cerebral Cortex

(2018) Brian E. Kalmbach et al.   NEURON

PANTHER version 14: more genomes, a new PANTHER GO-slim and improvements in enrichment analysis tools

(2018) Huaiyu Mi et al.   NUCLEIC ACIDS RESEARCH

Assessing Transcriptome Quality in Patch-Seq Datasets

(2018) Shreejoy J. Tripathy et al.   Frontiers in Molecular Neuroscience

Systems-based analysis of dendritic nonlinearities reveals temporal feature extraction in mouse L5 cortical neurons

(2017) Brian E. Kalmbach et al.   JOURNAL OF NEUROPHYSIOLOGY

Neuronal cell-type classification: challenges, opportunities and the path forward

(2017) Hongkui Zeng et al.   NATURE REVIEWS NEUROSCIENCE

Relationships between structure, in vivo function and long-range axonal target of cortical pyramidal tract neurons

(2017) Gerardo Rojas-Piloni et al.   Nature Communications

Roles of specific Kv channel types in repolarization of the action potential in genetically identified subclasses of pyramidal neurons in mouse neocortex

(2016) Dhruba Pathak et al.   JOURNAL OF NEUROPHYSIOLOGY

Adult mouse cortical cell taxonomy revealed by single cell transcriptomics

(2016) Bosiljka Tasic et al.   NATURE NEUROSCIENCE

A Designer AAV Variant Permits Efficient Retrograde Access to Projection Neurons

(2016) D. Gowanlock R. Tervo et al.   NEURON

Unique membrane properties and enhanced signal processing in human neocortical neurons

(2016) Guy Eyal et al.   eLife

Mammalian Brains Are Made of These: A Dataset of the Numbers and Densities of Neuronal and Nonneuronal Cells in the Brain of Glires, Primates, Scandentia, Eulipotyphlans, Afrotherians and Artiodactyls, and Their Relationship with Body Mass

(2015) Suzana Herculano-Houzel et al.   BRAIN BEHAVIOR AND EVOLUTION

Reconstruction and Simulation of Neocortical Microcircuitry

(2015) Henry Markram et al.   CELL

Dendritic and Axonal Architecture of Individual Pyramidal Neurons across Layers of Adult Human Neocortex

(2015) Hemanth Mohan et al.   CEREBRAL CORTEX

Electrophysiological properties of genetically identified subtypes of layer 5 neocortical pyramidal neurons: Ca2+ dependence and differential modulation by norepinephrine

(2015) Dongxu Guan et al.   JOURNAL OF NEUROPHYSIOLOGY

Temporal Dynamics of L5 Dendrites in Medial Prefrontal Cortex Regulate Integration Versus Coincidence Detection of Afferent Inputs

(2015) N. C. Dembrow et al.   JOURNAL OF NEUROSCIENCE

Distribution and Function of HCN Channels in the Apical Dendritic Tuft of Neocortical Pyramidal Neurons

(2015) M. T. Harnett et al.   JOURNAL OF NEUROSCIENCE

A motor cortex circuit for motor planning and movement

(2015) Nuo Li et al.   NATURE

The neocortical circuit: themes and variations

(2015) Kenneth D Harris et al.   NATURE NEUROSCIENCE

Dysfunction of Cortical Dendritic Integration in Neuropathic Pain Reversed by Serotoninergic Neuromodulation

(2015) Mirko Santello et al.   NEURON

Three Types of Cortical Layer 5 Neurons That Differ in Brain-wide Connectivity and Function

(2015) Euiseok J. Kim et al.   NEURON

Anatomy and physiology of the thick-tufted layer 5 pyramidal neuron

(2015) Srikanth Ramaswamy et al.   Frontiers in Cellular Neuroscience

Physiology of Layer 5 Pyramidal Neurons in Mouse Primary Visual Cortex: Coincidence Detection through Bursting

(2015) Adam S. Shai et al.   PLoS Computational Biology

Expression of the Developmental Transcription Factor Fezf2 Identifies a Distinct Subpopulation of Layer 5 Intratelencephalic-Projection Neurons in Mature Mouse Motor Cortex

(2014) M. L. S. Tantirigama et al.   JOURNAL OF NEUROSCIENCE

Subcircuit-specific neuromodulation in the prefrontal cortex

(2014) Nikolai Dembrow et al.   Frontiers in Neural Circuits

Correlated Gene Expression and Target Specificity Demonstrate Excitatory Projection Neuron Diversity

(2013) Staci A. Sorensen et al.   CEREBRAL CORTEX

Dendritic Generation of mGluR-Mediated Slow Afterdepolarization in Layer 5 Neurons of Prefrontal Cortex

(2013) B. E. Kalmbach et al.   JOURNAL OF NEUROSCIENCE

Potassium Channels Control the Interaction between Active Dendritic Integration Compartments in Layer 5 Cortical Pyramidal Neurons

(2013) Mark T. Harnett et al.   NEURON

Diversity of layer 5 projection neurons in the mouse motor cortex

(2013) Manfred J. Oswald et al.   Frontiers in Cellular Neuroscience

Large-Scale Cellular-Resolution Gene Profiling in Human Neocortex Reveals Species-Specific Molecular Signatures

(2012) Hongkui Zeng et al.   CELL

Intrinsic Electrophysiology of Mouse Corticospinal Neurons: a Class-Specific Triad of Spike-Related Properties

(2012) B. A. Suter et al.   CEREBRAL CORTEX

A cellular mechanism for cortical associations: an organizing principle for the cerebral cortex

(2012) Matthew Larkum   TRENDS IN NEUROSCIENCES

Selective serotonergic excitation of callosal projection neurons

(2012) Daniel Avesar et al.   Frontiers in Neural Circuits

Corticospinal-specific HCN expression in mouse motor cortex: Ih-dependent synaptic integration as a candidate microcircuit mechanism involved in motor control

(2011) Patrick L. Sheets et al.   JOURNAL OF NEUROPHYSIOLOGY

Long-Range Neuronal Circuits Underlying the Interaction between Sensory and Motor Cortex

(2011) Tianyi Mao et al.   NEURON

Projection-Specific Neuromodulation of Medial Prefrontal Cortex Neurons

(2010) N. C. Dembrow et al.   JOURNAL OF NEUROSCIENCE

Cell-Type Specific Properties of Pyramidal Neurons in Neocortex Underlying a Layout that Is Modifiable Depending on the Cortical Area

(2009) Alexander Groh et al.   CEREBRAL CORTEX

Thalamic Input to Distal Apical Dendrites in Neocortical Layer 1 Is Massive and Highly Convergent

(2009) Pablo Rubio-Garrido et al.   CEREBRAL CORTEX

Intracortical circuits of pyramidal neurons reflect their long-range axonal targets

(2009) Solange P. Brown et al.   NATURE

Firing-Pattern-Dependent Specificity of Cortical Excitatory Feed-Forward Subnetworks

(2008) T. Otsuka et al.   JOURNAL OF NEUROSCIENCE