The mechanosensory neurons of touch and their mechanisms of activation

The emergence of transcriptional identity in somatosensory neurons

(2020) Nikhil Sharma et al.   NATURE

Getting in Touch with Mechanical Pain Mechanisms

(2020) Rose Z. Hill et al.   TRENDS IN NEUROSCIENCES

Meissner corpuscles and their spatially intermingled afferents underlie gentle touch perception

(2020) Nicole L. Neubarth et al.   SCIENCE

USH2A is a Meissner’s corpuscle protein necessary for normal vibration sensing in mice and humans

(2020) Fred Schwaller et al.   NATURE NEUROSCIENCE

Decoding Cellular Mechanisms for Mechanosensory Discrimination

(2020) Lars J. von Buchholtz et al.   NEURON

Lamellar cells in Pacinian and Meissner corpuscles are touch sensors

(2020) Yury A. Nikolaev et al.   Science Advances

The morphology, size and density of the touch dome in human hairy skin by scanning electron microscopy

(2019) Yudai Kabata et al.   Microscopy

Tiling and somatotopic alignment of mammalian low-threshold mechanoreceptors

(2019) Emily D. Kuehn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of norepinephrine and β2 receptor antagonist ICI 118,551 on whisker hair follicle mechanoreceptors dissatisfy Merkel discs being adrenergic synapses

(2019) Mayumi Sonekatsu et al.   Molecular Brain

Deep Sequencing of Somatosensory Neurons Reveals Molecular Determinants of Intrinsic Physiological Properties

(2019) Yang Zheng et al.   NEURON

Specialized cutaneous Schwann cells initiate pain sensation

(2019) Hind Abdo et al.   SCIENCE

The mechanosensitive ion channel TRAAK is localized to the mammalian node of Ranvier

(2019) Stephen G Brohawn et al.   eLife

TREK-1 and TRAAK Are Principal K+ Channels at the Nodes of Ranvier for Rapid Action Potential Conduction on Mammalian Myelinated Afferent Nerves

(2019) Hirosato Kanda et al.   NEURON

Somatosensory innervation of the oral mucosa of adult and aging mice

(2018) Yalda Moayedi et al.   Scientific Reports

Keratinocytes mediate innocuous and noxious touch via ATP-P2X4 signaling

(2018) Francie Moehring et al.   eLife

Specialized mechanoreceptor systems in rodent glabrous skin

(2018) Jan Walcher et al.   JOURNAL OF PHYSIOLOGY-LONDON

Merkel Cells Activate Sensory Neural Pathways through Adrenergic Synapses

(2018) Benjamin U. Hoffman et al.   NEURON

PIEZO2 mediates injury-induced tactile pain in mice and humans

(2018) Marcin Szczot et al.   Science Translational Medicine

Merkel cells and Meissner's corpuscles in human digital skin display Piezo2 immunoreactivity

(2017) Y. García-Mesa et al.   JOURNAL OF ANATOMY

Touch Receptor-Derived Sensory Information Alleviates Acute Pain Signaling and Fine-Tunes Nociceptive Reflex Coordination

(2017) Alice Arcourt et al.   NEURON

Specialized Mechanosensory Nociceptors Mediating Rapid Responses to Hair Pull

(2017) Nima Ghitani et al.   NEURON

Active Touch and Self-Motion Encoding by Merkel Cell-Associated Afferents

(2017) Kyle S. Severson et al.   NEURON

Sparse genetic tracing reveals regionally specific functional organization of mammalian nociceptors

(2017) William Olson et al.   eLife

Diversity amongst trigeminal neurons revealed by high throughput single cell sequencing

(2017) Minh Q. Nguyen et al.   PLoS One

A multiphysics model of the Pacinian corpuscle

(2016) Julia C. Quindlen et al.   Integrative Biology

The Role of PIEZO2 in Human Mechanosensation

(2016) Alexander T. Chesler et al.   NEW ENGLAND JOURNAL OF MEDICINE

Evolutionary Specialization of Tactile Perception in Vertebrates

(2016) Eve R. Schneider et al.   PHYSIOLOGY

Correction to Supporting Information for Wilcox et al., Threat of plastic pollution to seabirds is global, pervasive, and increasing

(2016)   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic Identification of an Expansive Mechanoreceptor Sensitive to Skin Stroking

(2015) Ling Bai et al.   CELL

Somatosensory neuron types identified by high-coverage single-cell RNA-sequencing and functional heterogeneity

(2015) Chang-Lin Li et al.   CELL RESEARCH

Merkel cells and neurons keep in touch

(2015) Seung-Hyun Woo et al.   TRENDS IN CELL BIOLOGY

The Low-Threshold Calcium Channel Cav3.2 Determines Low-Threshold Mechanoreceptor Function

(2015) Amaury François et al.   Cell Reports

Merkel Cells Transduce and Encode Tactile Stimuli to Drive Aβ-Afferent Impulses

(2014) Ryo Ikeda et al.   CELL

The Cellular and Molecular Basis of Direction Selectivity of Aδ-LTMRs

(2014) Michael Rutlin et al.   CELL

Piezo2 is the major transducer of mechanical forces for touch sensation in mice

(2014) Sanjeev S. Ranade et al.   NATURE

Epidermal Merkel cells are mechanosensory cells that tune mammalian touch receptors

(2014) Srdjan Maksimovic et al.   NATURE

Piezo2 is required for Merkel-cell mechanotransduction

(2014) Seung-Hyun Woo et al.   NATURE

Edge-orientation processing in first-order tactile neurons

(2014) J Andrew Pruszynski et al.   NATURE NEUROSCIENCE

Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing

(2014) Dmitry Usoskin et al.   NATURE NEUROSCIENCE

Tuning Piezo ion channels to detect molecular-scale movements relevant for fine touch

(2014) Kate Poole et al.   Nature Communications

Diversification and Specialization of Touch Receptors in Skin

(2014) D. M. Owens et al.   Cold Spring Harbor Perspectives in Medicine

The structure and organization of lanceolate mechanosensory complexes at mouse hair follicles

(2014) Lishi Li et al.   eLife

Computation identifies structural features that govern neuronal firing properties in slowly adapting touch receptors

(2014) Daine R Lesniak et al.   eLife

Three-Dimensional Morphology of Touch Domes in Human Hairy Skin by Correlative Light and Scanning Electron Microscopy

(2013) Mari Orime et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The Transcription Factor c-Maf Controls Touch Receptor Development and Function

(2012) H. Wende et al.   SCIENCE

Morphologic diversity of cutaneous sensory afferents revealed by genetically directed sparse labeling

(2012) Hao Wu et al.   eLife

The Functional Organization of Cutaneous Low-Threshold Mechanosensory Neurons

(2011) Lishi Li et al.   CELL

The Cav3.2 T-type calcium channel regulates temporal coding in mouse mechanoreceptors

(2011) Rui Wang et al.   JOURNAL OF PHYSIOLOGY-LONDON

Laminin-332 coordinates mechanotransduction and growth cone bifurcation in sensory neurons

(2011) Li-Yang Chiang et al.   NATURE NEUROSCIENCE

KCNQ4 K+ channels tune mechanoreceptors for normal touch sensation in mouse and man

(2011) Matthias Heidenreich et al.   NATURE NEUROSCIENCE

Evidence for a protein tether involved in somatic touch

(2010) Jing Hu et al.   EMBO JOURNAL

The Regularity of Sustained Firing Reveals Two Populations of Slowly Adapting Touch Receptors in Mouse Hairy Skin

(2010) Scott A. Wellnitz et al.   JOURNAL OF NEUROPHYSIOLOGY

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

(2010) B. Coste et al.   SCIENCE

Cellular and Molecular Mechanisms of Pain

(2009) Allan I. Basbaum et al.   CELL

GABAergic/Glutamatergic-Glial/Neuronal Interaction Contributes to Rapid Adaptation in Pacinian Corpuscles

(2009) L. Pawson et al.   JOURNAL OF NEUROSCIENCE

Injury-induced mechanical hypersensitivity requires C-low threshold mechanoreceptors

(2009) Rebecca P. Seal et al.   NATURE

Coding of pleasant touch by unmyelinated afferents in humans

(2009) Line S Löken et al.   NATURE NEUROSCIENCE

Molecular Identification of Rapidly Adapting Mechanoreceptors and Their Developmental Dependence on Ret Signaling

(2009) Wenqin Luo et al.   NEURON

Low-Threshold Mechanoreceptor Subtypes Selectively Express MafA and Are Specified by Ret Signaling

(2009) Steeve Bourane et al.   NEURON

Distinct subsets of unmyelinated primary sensory fibers mediate behavioral responses to noxious thermal and mechanical stimuli

(2009) D. J. Cavanaugh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Merkel Cells Are Essential for Light-Touch Responses

(2009) S. M. Maricich et al.   SCIENCE

Identity of myelinated cutaneous sensory neurons projecting to nocireceptive laminae following nerve injury in adult mice

(2008) C. Jeffery Woodbury et al.   JOURNAL OF COMPARATIVE NEUROLOGY

The Meissner and Pacinian sensory corpuscles revisited new data from the last decade

(2008) José A. Vega et al.   MICROSCOPY RESEARCH AND TECHNIQUE

Three-dimensional analyses of touch domes in the hairy skin of the cat paw reveal morphological substrates for complex sensory processing

(2008) Satomi Ebara et al.   NEUROSCIENCE RESEARCH