4.6 Editorial Material

The emerging osteo-metabolic phenotype of COVID-19: clinical and pathophysiological aspects

Journal

NATURE REVIEWS ENDOCRINOLOGY
Volume 17, Issue 8, Pages 445-446

Publisher

NATURE PORTFOLIO
DOI: 10.1038/s41574-021-00516-y

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An emerging feature of COVID-19 is a clinically relevant osteo-metabolic phenotype characterized by acute hypocalcaemia and chronic hypovitaminosis D, with a high prevalence of vertebral fractures. This phenotype might have negative effects on disease severity and could potentially be targeted for prevention of SARS-CoV-2 infection and poor COVID-19 outcomes.
An emerging feature of COVID-19 is a clinically relevant osteo-metabolic phenotype characterized by widespread acute hypocalcaemia and chronic hypovitaminosis D with high prevalence of vertebral fractures. This phenotype might have negative effects on disease severity and its components could represent possible targets for prevention of SARS-CoV-2 infection and poor COVID-19 outcomes.

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