Sustained effects of rapidly acting antidepressants require BDNF-dependent MeCP2 phosphorylation

Single, Repeated, and Maintenance Ketamine Infusions for Treatment-Resistant Depression: A Randomized Controlled Trial

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CaM Kinase: Still Inspiring at 40

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Increasing doses of ketamine curtail antidepressant responses and suppress associated synaptic signaling pathways

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Calcium/Calmodulin-Dependent Protein Kinase II and Eukaryotic Elongation Factor 2 Kinase Pathways Mediate the Antidepressant Action of Ketamine

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Activity-Dependent Brain-Derived Neurotrophic Factor Release Is Required for the Rapid Antidepressant Actions of Scopolamine

(2018) Sriparna Ghosal et al.   BIOLOGICAL PSYCHIATRY

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Effects of a ketamine metabolite on synaptic NMDAR function

(2017) Kanzo Suzuki et al.   NATURE

Postnatal Loss of Mef2c Results in Dissociation of Effects on Synapse Number and Learning and Memory

(2016) Megumi Adachi et al.   BIOLOGICAL PSYCHIATRY

NMDAR inhibition-independent antidepressant actions of ketamine metabolites

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Essential roles of AMPA receptor GluA1 phosphorylation and presynaptic HCN channels in fast-acting antidepressant responses of ketamine

(2016) K. Zhang et al.   Science Signaling

Essential roles of AMPA receptor GluA1 phosphorylation and presynaptic HCN channels in fast-acting antidepressant responses of ketamine

(2016) K. Zhang et al.   Science Signaling

Activation of a ventral hippocampus–medial prefrontal cortex pathway is both necessary and sufficient for an antidepressant response to ketamine

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Rapid antidepressant actions of scopolamine: Role of medial prefrontal cortex and M1-subtype muscarinic acetylcholine receptors

(2015) Andrea Navarria et al.   NEUROBIOLOGY OF DISEASE

An acetylcholinesterase inhibitor, eserine, induces long-term depression at CA3-CA1 synapses in the hippocampus of adult rats

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Scopolamine Rapidly Increases Mammalian Target of Rapamycin Complex 1 Signaling, Synaptogenesis, and Antidepressant Behavioral Responses

(2013) Bhavya Voleti et al.   BIOLOGICAL PSYCHIATRY

Scopolamine and Ketamine: Evidence of Convergence?

(2013) Lisa M. Monteggia et al.   BIOLOGICAL PSYCHIATRY

Acute Suppression of Spontaneous Neurotransmission Drives Synaptic Potentiation

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Cholinergic signaling in the hippocampus regulates social stress resilience and anxiety- and depression-like behavior

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Rapid and Longer-Term Antidepressant Effects of Repeated Ketamine Infusions in Treatment-Resistant Major Depression

(2012) James W. Murrough et al.   BIOLOGICAL PSYCHIATRY

Nuclear Calcium Signaling Controls Methyl-CpG-binding Protein 2 (MeCP2) Phosphorylation on Serine 421 following Synaptic Activity

(2012) Bettina Buchthal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of MeCP2 at Ser421 Contributes to Chronic Antidepressant Action

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The Role of MeCP2 in the Brain

(2011) Jacky Guy et al.   Annual Review of Cell and Developmental Biology

Inhibition of glycogen synthase kinase-3 is necessary for the rapid antidepressant effect of ketamine in mice

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NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses

(2011) Anita E. Autry et al.   NATURE

Genome-Wide Activity-Dependent MeCP2 Phosphorylation Regulates Nervous System Development and Function

(2011) Sonia Cohen et al.   NEURON

Replication of Scopolamine's Antidepressant Efficacy in Major Depressive Disorder: A Randomized, Placebo-Controlled Clinical Trial

(2010) Wayne C. Drevets et al.   BIOLOGICAL PSYCHIATRY

Neuronal MeCP2 Is Expressed at Near Histone-Octamer Levels and Globally Alters the Chromatin State

(2010) Peter J. Skene et al.   MOLECULAR CELL

MeCP2 in the nucleus accumbens contributes to neural and behavioral responses to psychostimulants

(2010) Jie V Deng et al.   NATURE NEUROSCIENCE

mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists

(2010) N. Li et al.   SCIENCE

Safety and Efficacy of Repeated-Dose Intravenous Ketamine for Treatment-Resistant Depression

(2009) Marije aan het Rot et al.   BIOLOGICAL PSYCHIATRY

Transcription Factors in Long-Term Memory and Synaptic Plasticity

(2009) Cristina M. Alberini   PHYSIOLOGICAL REVIEWS

MEF2C, a transcription factor that facilitates learning and memory by negative regulation of synapse numbers and function

(2008) A. C. Barbosa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular Mechanisms Underlying the Antidepressant Effects of Ketamine: Role of α-Amino-3-Hydroxy-5-Methylisoxazole-4-Propionic Acid Receptors

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