HIV is associated with an increased risk of age-related clonal hematopoiesis among older adults

The First-in-Class Anti-CD47 Antibody Magrolimab (5F9) in Combination with Azacitidine Is Effective in MDS and AML Patients: Ongoing Phase 1b Results

(2020) David A Sallman et al.   BLOOD

Phase Ib Study of the Anti-TIM-3 Antibody MBG453 in Combination with Decitabine in Patients with High-Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML)

(2020) Uma Borate et al.   BLOOD

Luspatercept in Patients with Lower-Risk Myelodysplastic Syndromes

(2020) Pierre Fenaux et al.   NEW ENGLAND JOURNAL OF MEDICINE

Comparison of Overall and Comorbidity-Free Life Expectancy Between Insured Adults With and Without HIV Infection, 2000-2016

(2020) Julia L. Marcus et al.   JAMA Network Open

High-sensitivity C-reactive protein is associated with clonal hematopoiesis of indeterminate potential

(2020) Lambert Busque et al.   Blood Advances

Characteristics, Prevention, and Management of Cardiovascular Disease in People Living With HIV: A Scientific Statement From the American Heart Association

(2019) Matthew J. Feinstein et al.   CIRCULATION

HIV portends a poor prognosis in myelodysplastic syndromes

(2019) Justin D. Kaner et al.   LEUKEMIA & LYMPHOMA

Genetic IL-6 Signaling Deficiency Attenuates Cardiovascular Risk in Clonal Hematopoiesis

(2019) Alexander G. Bick et al.   CIRCULATION

Excess Risk for Atherosclerotic Cardiovascular Outcomes Among US Adults With HIV in the Current Era

(2019) Robert S. Rosenson et al.   Journal of the American Heart Association

Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host

(2018) Marlies Meisel et al.   NATURE

Somatic mutations precede acute myeloid leukemia years before diagnosis

(2018) Pinkal Desai et al.   NATURE MEDICINE

Prediction of acute myeloid leukaemia risk in healthy individuals

(2018) Sagi Abelson et al.   NATURE

Inhibition of Inflammatory Signaling in Tet2 Mutant Preleukemic Cells Mitigates Stress-Induced Abnormalities and Clonal Hematopoiesis

(2018) Zhigang Cai et al.   Cell Stem Cell

Role of Donor Clonal Hematopoiesis in Allogeneic Hematopoietic Stem-Cell Transplantation

(2018) Mareike Frick et al.   JOURNAL OF CLINICAL ONCOLOGY

Global and regional trends of people living with HIV aged 50 and over: Estimates and projections for 2000–2020

(2018) Christine S. Autenrieth et al.   PLoS One

Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease

(2017) Siddhartha Jaiswal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice

(2017) José J. Fuster et al.   SCIENCE

ASXL1 c.1934dup;p.Gly646Trpfs*12—a true somatic alteration requiring a new approach

(2017) Costas K. Yannakou et al.   Blood Cancer Journal

Evolving epidemiology of HIV-associated malignancies

(2017) Meredith S. Shiels et al.   Current Opinion in HIV and AIDS

PathOS: a decision support system for reporting high throughput sequencing of cancers in clinical diagnostic laboratories

(2017) Kenneth D. Doig et al.   Genome Medicine

Life expectancy in HIV-positive persons in Switzerland

(2016) Aysel Gueler et al.   AIDS

Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal

(2016) Eric M. Pietras et al.   NATURE CELL BIOLOGY

Relevance of Interleukin-6 and D-Dimer for Serious Non-AIDS Morbidity and Death among HIV-Positive Adults on Suppressive Antiretroviral Therapy

(2016) Birgit Grund et al.   PLoS One

Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology

(2015) Sue Richards et al.   GENETICS IN MEDICINE

Effect of CD4+ cell count and viral suppression on risk of ischemic stroke in HIV infection

(2014) Felicia C. Chow et al.   AIDS

Cross-sectional Comparison of the Prevalence of Age-Associated Comorbidities and Their Risk Factors Between HIV-Infected and Uninfected Individuals: The AGEhIV Cohort Study

(2014) J. Schouten et al.   CLINICAL INFECTIOUS DISEASES

Re-entry into quiescence protects hematopoietic stem cells from the killing effect of chronic exposure to type I interferons

(2014) Eric M. Pietras et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Age-related mutations associated with clonal hematopoietic expansion and malignancies

(2014) Mingchao Xie et al.   NATURE MEDICINE

Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence

(2014) Giulio Genovese et al.   NEW ENGLAND JOURNAL OF MEDICINE

Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes

(2014) Siddhartha Jaiswal et al.   NEW ENGLAND JOURNAL OF MEDICINE

IL-1Β Enriched Monocytes Mount Massive IL-6 Responses to Common Inflammatory Triggers among Chronically HIV-1 Infected Adults on Stable Anti-Retroviral Therapy at Risk for Cardiovascular Disease

(2013) Emilie Jalbert et al.   PLoS One

Morbidity and Aging in HIV-Infected Persons: The Swiss HIV Cohort Study

(2011) B. Hasse et al.   CLINICAL INFECTIOUS DISEASES

Association of Immunologic and Virologic Factors With Myocardial Infarction Rates in a US Healthcare System

(2010) Virginia A Triant et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Persistent Microbial Translocation and Immune Activation in HIV‐1–Infected South Africans Receiving Combination Antiretroviral Therapy

(2010) Edana Cassol et al.   JOURNAL OF INFECTIOUS DISEASES

Markers of Inflammation, Coagulation, and Renal Function Are Elevated in Adults with HIV Infection

(2010) Jacqueline Neuhaus et al.   JOURNAL OF INFECTIOUS DISEASES

Inflammatory and Coagulation Biomarkers and Mortality in Patients with HIV Infection

(2008) Lewis H Kuller et al.   PLOS MEDICINE