Transcriptional processing of an unnatural base pair by eukaryotic RNA polymerase II

RNA polymerase II stalls on oxidative DNA damage via a torsion-latch mechanism involving lone pair–π and CH–π interactions

(2020) Juntaek Oh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural and biochemical analysis of DNA lesion-induced RNA polymerase II arrest

(2019) Juntaek Oh et al.   METHODS

Optimization of Replication, Transcription, and Translation in a Semi-Synthetic Organism

(2019) Aaron W. Feldman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Progress toward Eukaryotic Semisynthetic Organisms: Translation of Unnatural Codons

(2019) Anne Xiao-Zhou Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural basis of transcriptional stalling and bypass of abasic DNA lesion by RNA polymerase II

(2018) Wei Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A semi-synthetic organism that stores and retrieves increased genetic information

(2017) Yorke Zhang et al.   NATURE

A semisynthetic organism engineered for the stable expansion of the genetic alphabet

(2017) Yorke Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The landscape of transcription errors in eukaryotic cells

(2017) Jean-Francois Gout et al.   Science Advances

The Expanded Genetic Alphabet

(2015) Denis A. Malyshev et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mechanism of RNA polymerase II bypass of oxidative cyclopurine DNA lesions

(2015) Celine Walmacq et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A semi-synthetic organism with an expanded genetic alphabet

(2014) Denis A. Malyshev et al.   NATURE

Five checkpoints maintaining the fidelity of transcription by RNA polymerases in structural and energetic details

(2014) Beibei Wang et al.   NUCLEIC ACIDS RESEARCH

Millisecond dynamics of RNA polymerase II translocation at atomic resolution

(2014) D.-A. Silva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How good are my data and what is the resolution?

(2013) Philip R. Evans et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Natural-like Replication of an Unnatural Base Pair for the Expansion of the Genetic Alphabet and Biotechnology Applications

(2013) Lingjun Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural Insights into DNA Replication without Hydrogen Bonds

(2013) Karin Betz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Basic mechanism of transcription by RNA polymerase II

(2012) Vladimir Svetlov et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

RNA polymerase II transcription: Structure and mechanism

(2012) Xin Liu et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Mechanism of Translesion Transcription by RNA Polymerase II and Its Role in Cellular Resistance to DNA Damage

(2012) Celine Walmacq et al.   MOLECULAR CELL

KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry

(2012) Karin Betz et al.   Nature Chemical Biology

iMOSFLM: a new graphical interface for diffraction-image processing withMOSFLM

(2011) T. Geoff G. Battye et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The Catalytic Mechanism of RNA Polymerase II

(2011) Alexandra T. P. Carvalho et al.   Journal of Chemical Theory and Computation

Site-Specific Labeling of DNA and RNA Using an Efficiently Replicated and Transcribed Class of Unnatural Base Pairs

(2011) Young Jun Seo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dynamics of Pyrophosphate Ion Release and Its Coupled Trigger Loop Motion from Closed to Open State in RNA Polymerase II

(2011) Lin-Tai Da et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural basis of RNA polymerase II backtracking, arrest and reactivation

(2011) Alan C. M. Cheung et al.   NATURE

Evolution of multisubunit RNA polymerases in the three domains of life

(2011) Finn Werner et al.   NATURE REVIEWS MICROBIOLOGY

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Solution Structure, Mechanism of Replication, and Optimization of an Unnatural Base Pair

(2010) Denis A. Malyshev et al.   CHEMISTRY-A EUROPEAN JOURNAL

RNA polymerase II trigger loop residues stabilize and position the incoming nucleotide triphosphate in transcription

(2010) X. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Improved side-chain torsion potentials for the Amber ff99SB protein force field

(2010) Kresten Lindorff-Larsen et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Transcription of an Expanded Genetic Alphabet

(2009) Young Jun Seo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural Basis of Transcription: Mismatch-Specific Fidelity Mechanisms and Paused RNA Polymerase II with Frayed RNA

(2009) Jasmin F. Sydow et al.   MOLECULAR CELL

Structural Basis of Transcription: Backtracked RNA Polymerase II at 3.4 Angstrom Resolution

(2009) D. Wang et al.   SCIENCE