Clonal fitness inferred from time-series modelling of single-cell cancer genomes

The evolutionary history of 2,658 cancers

(2020) Moritz Gerstung et al.   NATURE

Patterns of somatic structural variation in human cancer genomes

(2020) Yilong Li et al.   NATURE

Interplay between whole-genome doubling and the accumulation of deleterious alterations in cancer evolution

(2020) Saioa López et al.   NATURE GENETICS

Estimating growth patterns and driver effects in tumor evolution from individual samples

(2020) Leonidas Salichos et al.   Nature Communications

Exploiting evolutionary steering to induce collateral drug sensitivity in cancer

(2020) Ahmet Acar et al.   Nature Communications

Exact simulation for multivariate Itô diffusions

(2020) Jose Blanchet et al.   ADVANCES IN APPLIED PROBABILITY

Context is everything: aneuploidy in cancer

(2019) Uri Ben-David et al.   NATURE REVIEWS GENETICS

Clonal Decomposition and DNA Replication States Defined by Scaled Single-Cell Genome Sequencing

(2019) Emma Laks et al.   CELL

A view on drug resistance in cancer

(2019) Neil Vasan et al.   NATURE

NRF2 and the Hallmarks of Cancer

(2018) Montserrat Rojo de la Vega et al.   CANCER CELL

Chromosomal instability drives metastasis through a cytosolic DNA response

(2018) Samuel F. Bakhoum et al.   NATURE

Genome doubling shapes the evolution and prognosis of advanced cancers

(2018) Craig M. Bielski et al.   NATURE GENETICS

Quantification of subclonal selection in cancer from bulk sequencing data

(2018) Marc J. Williams et al.   NATURE GENETICS

Longitudinal Liquid Biopsy and Mathematical Modeling of Clonal Evolution Forecast Time to Treatment Failure in the PROSPECT-C Phase II Colorectal Cancer Clinical Trial

(2018) Khurum H. Khan et al.   Cancer Discovery

The dynamics of molecular evolution over 60,000 generations

(2017) Benjamin H. Good et al.   NATURE

Tracking the Evolution of Non–Small-Cell Lung Cancer

(2017) Mariam Jamal-Hanjani et al.   NEW ENGLAND JOURNAL OF MEDICINE

Tumor aneuploidy correlates with markers of immune evasion and with reduced response to immunotherapy

(2017) Teresa Davoli et al.   SCIENCE

On the exact and $\varepsilon$-strong simulation of (jump) diffusions

(2016) Murray Pollock et al.   BERNOULLI

An Approximate Markov Model for the Wright–Fisher Diffusion and Its Application to Time Series Data

(2016) Anna Ferrer-Admetlla et al.   GENETICS

Landscape of somatic mutations in 560 breast cancer whole-genome sequences

(2016) Serena Nik-Zainal et al.   NATURE

Divergent modes of clonal spread and intraperitoneal mixing in high-grade serous ovarian cancer

(2016) Andrew McPherson et al.   NATURE GENETICS

Identification of neutral tumor evolution across cancer types

(2016) Marc J Williams et al.   NATURE GENETICS

An Approximate Markov Model for the Wright–Fisher Diffusion and Its Application to Time Series Data

(2016) Anna Ferrer-Admetlla et al.   GENETICS

Whole–genome characterization of chemoresistant ovarian cancer

(2015) Ann-Marie Patch et al.   NATURE

The Fitness Consequences of Aneuploidy Are Driven by Condition-Dependent Gene Effects

(2015) Anna B. Sunshine et al.   PLOS BIOLOGY

Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution

(2014) Peter Eirew et al.   NATURE

Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing

(2014) Marco Gerlinger et al.   NATURE GENETICS

PyClone: statistical inference of clonal population structure in cancer

(2014) Andrew Roth et al.   NATURE METHODS

Influenza Virus Drug Resistance: A Time-Sampled Population Genetics Perspective

(2014) Matthieu Foll et al.   PLoS Genetics

Enhanced tumor suppression by adenoviral PTEN gene therapy combined with cisplatin chemotherapy in small-cell lung cancer

(2013) D Li et al.   CANCER GENE THERAPY

Klotho Sensitizes Human Lung Cancer Cell Line to Cisplatin via PI3k/Akt Pathway

(2013) Yan Wang et al.   PLoS One

The Life History of 21 Breast Cancers

(2012) Serena Nik-Zainal et al.   CELL

Estimating Allele Age and Selection Coefficient from Time-Serial Data

(2012) A.-S. Malaspinas et al.   GENETICS

The clonal and mutational evolution spectrum of primary triple-negative breast cancers

(2012) Sohrab P. Shah et al.   NATURE

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

(2012) Christina Curtis et al.   NATURE

Transcriptional consequences of aneuploidy

(2012) J. M. Sheltzer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adaptive approximate Bayesian computation

(2009) M. A. Beaumont et al.   BIOMETRIKA

Estimation of 2Nes From Temporal Allele Frequency Data

(2008) J. P. Bollback et al.   GENETICS