Bone mesenchymal stem cell-derived exosome-loaded injectable hydrogel for minimally invasive treatment of spinal cord injury

A bioactive injectable self-healing anti-inflammatory hydrogel with ultralong extracellular vesicles release synergistically enhances motor functional recovery of spinal cord injury

(2021) Chenggui Wang et al.   Bioactive Materials

Biomaterials Functionalized with MSC Secreted Extracellular Vesicles and Soluble Factors for Tissue Regeneration

(2020) Meadhbh Á. Brennan et al.   ADVANCED FUNCTIONAL MATERIALS

Transplantation of Human Mesenchymal Stem-Cell-Derived Exosomes Immobilized in an Adhesive Hydrogel for Effective Treatment of Spinal Cord Injury

(2020) Liming Li et al.   NANO LETTERS

The effect of a nanofiber-hydrogel composite on neural tissue repair and regeneration in the contused spinal cord

(2020) Xiaowei Li et al.   BIOMATERIALS

An anti-inflammatory peptide and brain-derived neurotrophic factor-modified hyaluronan-methylcellulose hydrogel promotes nerve regeneration in rats with spinal cord injury

(2019) Zhijiang He et al.   International Journal of Nanomedicine

Biomimetic 3D-printed scaffolds for spinal cord injury repair

(2019) Jacob Koffler et al.   NATURE MEDICINE

Exosomes from Human Gingiva-Derived Mesenchymal Stem Cells Combined with Biodegradable Chitin Conduits Promote Rat Sciatic Nerve Regeneration

(2019) Feng Rao et al.   Stem Cells International

A hydrogel engineered to deliver minocycline locally to the injured cervical spinal cord protects respiratory neural circuitry and preserves diaphragm function

(2019) Biswarup Ghosh et al.   NEUROBIOLOGY OF DISEASE

Chitosan-based hydrogel to support the paracrine activity of mesenchymal stem cells in spinal cord injury treatment

(2019) M. Boido et al.   Scientific Reports

A MnO2 Nanoparticle-Dotted Hydrogel Promotes Spinal Cord Repair via Regulating Reactive Oxygen Species Microenvironment and Synergizing with Mesenchymal Stem Cells

(2019) Liming Li et al.   ACS Nano

Oligonucleotide-functionalized hydrogels for sustained release of small molecule (aptamer) therapeutics

(2019) Nikunj K. Agrawal et al.   Acta Biomaterialia

The translational landscape in spinal cord injury: focus on neuroplasticity and regeneration

(2019) Thomas H. Hutson et al.   Nature Reviews Neurology

Extracellular Vesicles Can Deliver Anti-inflammatory and Anti-scarring Activities of Mesenchymal Stromal Cells After Spinal Cord Injury

(2019) Pasquale Romanelli et al.   Frontiers in Neurology

Bone marrow mesenchymal stem cells encapsulated thermal-responsive hydrogel network bridges combined photo-plasmonic nanoparticulate system for the treatment of urinary bladder dysfunction after spinal cord injury

(2019) Hengyuan An et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Motor and sensitive recovery after injection of a physically cross-linked PNIPAAm-g-PEG hydrogel in rat hemisectioned spinal cord

(2019) Maxime Bonnet et al.   Materials Science & Engineering C-Materials for Biological Applications

Directing Induced Pluripotent Stem Cell Derived Neural Stem Cell Fate with a Three-Dimensional Biomimetic Hydrogel for Spinal Cord Injury Repair

(2018) Lei Fan et al.   ACS Applied Materials & Interfaces

Stem cell-inspired secretome-rich injectable hydrogel to repair injured cardiac tissue

(2018) Renae Waters et al.   Acta Biomaterialia

Sustained-release of FGF-2 from a hybrid hydrogel of heparin-poloxamer and decellular matrix promotes the neuroprotective effects of proteins after spinal injury

(2018) He-Lin Xu et al.   International Journal of Nanomedicine

hucMSC derived exosomes promote functional recovery in spinal cord injury mice via attenuating inflammation

(2018) Guodong Sun et al.   Materials Science & Engineering C-Materials for Biological Applications

Injectable Nanoreinforced Shape-Memory Hydrogel System for Regenerating Spinal Cord Tissue from Traumatic Injury

(2018) Chong Wang et al.   ACS Applied Materials & Interfaces

Enhanced Therapeutic Effects of Mesenchymal Stem Cell-Derived Exosomes with an Injectable Hydrogel for Hindlimb Ischemia Treatment

(2018) Kaiyue Zhang et al.   ACS Applied Materials & Interfaces

Injectable, Magnetically Orienting Electrospun Fiber Conduits for Neuron Guidance

(2018) Christopher D. L. Johnson et al.   ACS Applied Materials & Interfaces

Soft Conducting Polymer Hydrogels Cross-Linked and Doped by Tannic Acid for Spinal Cord Injury Repair

(2018) Lei Zhou et al.   ACS Nano

The Healing Effects of Conditioned Medium Derived from Mesenchymal Stem Cells on Radiation-Induced Skin Wounds in Rats

(2018) JiaYang Sun et al.   CELL TRANSPLANTATION

Systemic Administration of Exosomes Released from Mesenchymal Stromal Cells Attenuates Apoptosis, Inflammation, and Promotes Angiogenesis after Spinal Cord Injury in Rats

(2017) Jiang-Hu Huang et al.   JOURNAL OF NEUROTRAUMA

Nerve Cells Decide to Orient inside an Injectable Hydrogel with Minimal Structural Guidance

(2017) Jonas C. Rose et al.   NANO LETTERS

An injectable hydrogel enhances tissue repair after spinal cord injury by promoting extracellular matrix remodeling

(2017) Le Thi Anh Hong et al.   Nature Communications

Traumatic spinal cord injury

(2017) Christopher S. Ahuja et al.   Nature Reviews Disease Primers

Using NGF heparin-poloxamer thermosensitive hydrogels to enhance the nerve regeneration for spinal cord injury

(2016) Ying-Zheng Zhao et al.   Acta Biomaterialia

Injectable hydrogel promotes early survival of induced pluripotent stem cell-derived oligodendrocytes and attenuates longterm teratoma formation in a spinal cord injury model

(2016) T. Führmann et al.   BIOMATERIALS

Injectable Extracellular Matrix Hydrogels as Scaffolds for Spinal Cord Injury Repair

(2016) Dmitry Tukmachev et al.   TISSUE ENGINEERING PART A

Modulating in vivo degradation rate of injectable extracellular matrix hydrogels

(2016) Jean W. Wassenaar et al.   Journal of Materials Chemistry B

An Injectable, Calcium Responsive Composite Hydrogel for the Treatment of Acute Spinal Cord Injury

(2014) Christopher A. McKay et al.   ACS Applied Materials & Interfaces