Inherited and acquired corona of coronavirus in the host: Inspiration from the biomolecular corona of nanoparticles

The family of coronavirus are named for their crown shape. Encoded by the genetic material inherited from the coronavirus itself, this intrinsic well-known viral corona is considered an inherited corona. After contact with mucosa or the entrance into the host, bare coronaviruses can become covered by a group of dissolved biomolecules to form one or multiple layers of biomolecules. The layers acquired from the sur-rounding environment are named the acquired corona. We highlight here the possible role of the acquired corona in the pathogenesis of coronaviruses, which will generate fresh insight into the nature of various coronavirus-host interactions. (c) 2021 Elsevier Ltd. All rights reserved.

Automated summary

Coronaviruses are named for their crown shape and consist of inherited and acquired coronas. The acquired corona may play a significant role in the pathogenesis of coronaviruses, providing new insights into the nature of coronavirus-host interactions.