Molecular targets for anticancer redox chemotherapy and cisplatin-induced ototoxicity: the role of curcumin on pSTAT3 and Nrf-2 signalling

A Curcumin Derivative That Inhibits Vinyl Carbamate-Induced Lung Carcinogenesis via Activation of the Nrf2 Protective Response

(2015) Tao Shen et al.   ANTIOXIDANTS & REDOX SIGNALING

Rosmarinic acid up-regulates the noise-activated Nrf2/HO-1 pathway and protects against noise-induced injury in rat cochlea

(2015) A.R. Fetoni et al.   FREE RADICAL BIOLOGY AND MEDICINE

Review of STAT3 (Signal Transducers and Activators of Transcription) in head and neck cancer

(2015) Shrikant Balasaheb Mali   ORAL ONCOLOGY

Reactive oxygen species-mediated therapeutic response and resistance in glioblastoma

(2015) E Singer et al.   Cell Death & Disease

Curcumin nanoformulations: A review of pharmaceutical properties and preclinical studies and clinical data related to cancer treatment

(2014) Ornchuma Naksuriya et al.   BIOMATERIALS

Curcuma Longa (Curcumin) Decreases In Vivo Cisplatin-Induced Ototoxicity Through Heme Oxygenase-1 Induction

(2014) Anna R. Fetoni et al.   OTOLOGY & NEUROTOLOGY

A Novel Curcumin Analog (H-4073) Enhances the Therapeutic Efficacy of Cisplatin Treatment in Head and Neck Cancer

(2014) Bhavna Kumar et al.   PLoS One

WP1066 Sensitizes Oral Squamous Cell Carcinoma Cells to Cisplatin by Targeting STAT3/miR-21 axis

(2014) Xuan Zhou et al.   Scientific Reports

Recent Developments in Delivery, Bioavailability, Absorption and Metabolism of Curcumin: the Golden Pigment from Golden Spice

(2014) Sahdeo Prasad et al.   Cancer Research and Treatment

Nanotechnology-Applied Curcumin for Different Diseases Therapy

(2014) Negar Ghalandarlaki et al.   Biomed Research International

A novel small molecule that induces oxidative stress and selectively kills malignant cells

(2013) Francesca R. Šalipur et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cisplatin-induced ototoxicity: Transporters playing a role in cisplatin toxicity

(2013) Sofia Waissbluth et al.   HEARING RESEARCH

Noise-Induced Hearing Loss (NIHL) as a Target of Oxidative Stress-Mediated Damage: Cochlear and Cortical Responses after an Increase in Antioxidant Defense

(2013) A. R. Fetoni et al.   JOURNAL OF NEUROSCIENCE

Stat3 Inhibitor Stattic Exhibits Potent Antitumor Activity and Induces Chemo- and Radio-Sensitivity in Nasopharyngeal Carcinoma

(2013) Yunbao Pan et al.   PLoS One

Cytotoxic Effects of Curcumin in Human Retinal Pigment Epithelial Cells

(2013) Margrit Hollborn et al.   PLoS One

Clinical Significance of Keap1 and Nrf2 in Oral Squamous Cell Carcinoma

(2013) Cong-Fa Huang et al.   PLoS One

Understanding platinum-induced ototoxicity

(2013) Thorsten Langer et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Glutathione-S-Transferases As Determinants of Cell Survival and Death

(2012) Kenneth D. Tew et al.   ANTIOXIDANTS & REDOX SIGNALING

Molecular mechanisms of curcumin action: Gene expression

(2012) Shishir Shishodia   BIOFACTORS

The Targets of Curcumin

(2012) Hongyu Zhou et al.   CURRENT DRUG TARGETS

Establishing cellular stress response profiles as biomarkers of homeodynamics, health and hormesis

(2012) Dino Demirovic et al.   EXPERIMENTAL GERONTOLOGY

Synergic effect of curcumin or lycopene with irradiation upon oral squamous cell carcinoma cells

(2012) F Camacho-Alonso et al.   ORAL DISEASES

Dietary phytochemicals and cancer prevention: Nrf2 signaling, epigenetics, and cell death mechanisms in blocking cancer initiation and progression

(2012) Jong Hun Lee et al.   PHARMACOLOGY & THERAPEUTICS

Sensitization of Head and Neck Cancer to Cisplatin Through the Use of a Novel Curcumin Analog

(2011) Waleed M. Abuzeid et al.   ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY

The Role of NF-E2-Related Factor 2 in Predicting Chemoresistance and Prognosis in Advanced Non–Small-Cell Lung Cancer

(2011) Haihong Yang et al.   Clinical Lung Cancer

STAT3 SIGNALING: Anticancer Strategies and Challenges

(2011) P. A. Johnston et al.   MOLECULAR INTERVENTIONS

Molecular mechanisms of cisplatin resistance

(2011) L Galluzzi et al.   ONCOGENE

Defining the role of the JAK-STAT pathway in head and neck and thoracic malignancies: Implications for future therapeutic approaches

(2010) Stephen Y. Lai et al.   DRUG RESISTANCE UPDATES

Curcumin, the Golden Spice From Indian Saffron, Is a Chemosensitizer and Radiosensitizer for Tumors and Chemoprotector and Radioprotector for Normal Organs

(2010) Ajay Goel et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Redox-Directed Cancer Therapeutics: Molecular Mechanisms and Opportunities

(2009) Georg T. Wondrak   ANTIOXIDANTS & REDOX SIGNALING

Guggulsterone enhances head and neck cancer therapies via inhibition of signal transducer and activator of transcription-3

(2009) Rebecca J. Leeman-Neill et al.   CARCINOGENESIS

Cisplatin Ototoxicity and Protection: Clinical and Experimental Studies

(2009) Leonard P Rybak et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer

(2009) John D. Hayes et al.   TRENDS IN BIOCHEMICAL SCIENCES

Liposome-Encapsulated Curcumin Suppresses Growth of Head and Neck Squamous Cell Carcinoma In vitro and in Xenografts through the Inhibition of Nuclear Factor  B by an AKT-Independent Pathway

(2008) D. Wang et al.   CLINICAL CANCER RESEARCH

A signal network involving coactivated NF-κB and STAT3 and altered p53 modulates BAX/BCL-XL expression and promotes cell survival of head and neck squamous cell carcinomas

(2008) Tin Lap Lee et al.   INTERNATIONAL JOURNAL OF CANCER

Activation of Signal Transducers and Activators of Transcription 3 and Overexpression of its Target Gene CyclinD1 in Laryngeal Carcinomas

(2008) Bin Liu et al.   LARYNGOSCOPE

Curcumin and the cellular stress response in free radical-related diseases

(2008) Vittorio Calabrese et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Cancer-related inflammation

(2008) Alberto Mantovani et al.   NATURE

Curcumin: Preventive and Therapeutic Properties in Laboratory Studies and Clinical Trials

(2007) Alexios S. Strimpakos et al.   ANTIOXIDANTS & REDOX SIGNALING