Enhancement of the Antioxidant and Skin Permeation Properties of Betulin and Its Derivatives

Skin Penetration Enhancement Strategies Used in the Development of Melanoma Topical Treatments

(2021) Supreeda Tambunlertchai et al.   AAPS Journal

Bioactive Betulin and PEG Based Polyanhydrides for Use in Drug Delivery Systems

(2021) Daria Niewolik et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cosmetic and Dermatological Properties of Selected Ayurvedic Plant Extracts

(2021) Martyna Zagórska-Dziok et al.   MOLECULES

In Vitro Human Skin Penetration, Antioxidant and Antimicrobial Activity of Ethanol-Water Extract of Fireweed (Epilobium angustifolium L.)

(2021) Anna Nowak et al.   MOLECULES

Enhancement strategies for transdermal drug delivery systems: current trends and applications

(2021) Delly Ramadon et al.   Drug Delivery and Translational Research

Proniosomal Gel for Topical Delivery of Rutin: Preparation, Physicochemical Characterization and In Vitro Toxicological Profile Using 3D Reconstructed Human Epidermis Tissue and 2D Cells

(2021) Iulia Pinzaru et al.   Antioxidants

Functionalization of Betulinic Acid with Polyphenolic Fragments for the Development of New Amphiphilic Antioxidants

(2021) Joana L. C. Sousa et al.   Antioxidants

Mycelial culture extracts of selected wood-decay mushrooms as a source of skin-protecting factors

(2021) Katarzyna Sułkowska-Ziaja et al.   BIOTECHNOLOGY LETTERS

Chromatographic and Computational Screening of Lipophilicity and Pharmacokinetics of Newly Synthesized Betulin-1,4-quinone Hybrids

(2021) Monika Kadela-Tomanek et al.   Processes

Mitochondria-targeted prooxidant effects of betulinic acid conjugated with delocalized lipophilic cation F16

(2021) Mikhail V. Dubinin et al.   FREE RADICAL BIOLOGY AND MEDICINE

Wound Healing Composite Materials of Bacterial Cellulose and Zinc Oxide Nanoparticles with Immobilized Betulin Diphosphate

(2021) Nina Melnikova et al.   Nanomaterials

The Effect of Cream and Gel Vehicles on the Percutaneous Absorption and Skin Retention of a New Eugenol Derivative With Antioxidant Activity

(2021) Edyta Makuch et al.   Frontiers in Pharmacology

The Role of Oxidative Stress in Physiopathology and Pharmacological Treatment with Pro- and Antioxidant Properties in Chronic Diseases

(2020) Andrés García-Sánchez et al.   Oxidative Medicine and Cellular Longevity

Control of Reactive Oxygen Species for the Prevention of Parkinson’s Disease: The Possible Application of Flavonoids

(2020) Tae Yeon Kim et al.   Antioxidants

Enhancement of the antioxidant and skin permeation properties of eugenol by the esterification of eugenol to new derivatives

(2020) Edyta Makuch et al.   AMB Express

Oxidative Stress: Concept and Some Practical Aspects

(2020) Helmut Sies   Antioxidants

Recent Developments in the Functionalization of Betulinic Acid and Its Natural Analogues: A Route to New Bioactive Compounds

(2019) Joana L. C. Sousa et al.   MOLECULES

Application of TLC for Evaluation of the Lipophilicity of Newly Synthetized Esters: Betulin Derivatives

(2019) Katarzyna Bober et al.   Journal of Analytical Methods in Chemistry

New phosphate derivatives of betulin as anticancer agents: Synthesis, crystal structure, and molecular docking study

(2019) Elwira Chrobak et al.   BIOORGANIC CHEMISTRY

Synthesis and cytotoxicity of new alkyne derivatives of pentacyclic triterpenoids

(2019) E. Yu. Yamansarov et al.   RUSSIAN CHEMICAL BULLETIN

Betulin and its derivatives as novel compounds with different pharmacological effects

(2019) Shayan Amiri et al.   BIOTECHNOLOGY ADVANCES

Transcriptomic Analysis Reveals the Roles of Detoxification Systems in Response to Mercury in Chromera velia

(2019) Sharaf et al.   Biomolecules

Application of TLC to Evaluate the Lipophilicity of Newly Synthesized Betulin Derivatives

(2019) Ewa Bębenek et al.   JOURNAL OF CHROMATOGRAPHIC SCIENCE

The potent insulin secretagogue effect of betulinic acid is mediated by potassium and chloride channels

(2018) Allisson Jhonatan Gomes Castro et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Oxidative stress, aging, and diseases

(2018) Ilaria Liguori et al.   Clinical Interventions in Aging

Application of nanoparticles in percutaneous delivery of active ingredients in cosmetic preparations

(2018) Khadijeh Khezri et al.   BIOMEDICINE & PHARMACOTHERAPY

Stimuli-Responsive Therapeutic Metallodrugs

(2018) Xiaohui Wang et al.   CHEMICAL REVIEWS

Development and evaluation of long-circulating nanoparticles loaded with betulinic acid for improved anti-tumor efficacy

(2017) Ankit Saneja et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Synthesis, Anti-Breast Cancer Activity, and Molecular Docking Study of a New Group of Acetylenic Quinolinesulfonamide Derivatives

(2017) Krzysztof Marciniec et al.   MOLECULES

Galactosyl Pentadecene Reversibly Enhances Transdermal and Topical Drug Delivery

(2017) Monika Kopečná et al.   PHARMACEUTICAL RESEARCH

Pharmacokinetics and Tissue Disposition of Nanosystem-Entrapped Betulin After Endotracheal Administration to Rats

(2016) Olga N. Pozharitskaya et al.   EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS

Oleanolic, Ursolic, and Betulinic Acids as Food Supplements or Pharmaceutical Agents for Type 2 Diabetes: Promise or Illusion?

(2016) Filomena S. G. Silva et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

New acetylenic derivatives of betulin and betulone, synthesis and cytotoxic activity

(2016) Ewa Bębenek et al.   MEDICINAL CHEMISTRY RESEARCH

The role of antioxidants in the chemistry of oxidative stress: A review

(2015) Aurelia Magdalena Pisoschi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Medicinal plants of the genus Betula—Traditional uses and a phytochemical–pharmacological review

(2015) Subha Rastogi et al.   JOURNAL OF ETHNOPHARMACOLOGY

Cellular Mechanisms of Oxidative Stress and Action in Melanoma

(2015) Mario Venza et al.   Oxidative Medicine and Cellular Longevity

Polyamine derivatives of betulinic acid and β-sitosterol: A comparative investigation

(2015) Uladzimir Bildziukevich et al.   STEROIDS

Lipid nanoparticles as novel delivery systems for cosmetics and dermal pharmaceuticals

(2012) Carmelo Puglia et al.   Expert Opinion on Drug Delivery

Betulinic acid delivered in liposomes reduces growth of human lung and colon cancers in mice without causing systemic toxicity

(2011) Franziska B. Mullauer et al.   ANTI-CANCER DRUGS

Transdermal Drug Delivery Enhancement by Compounds of Natural Origin

(2011) Lizelle T. Fox et al.   MOLECULES

Drug delivery through the skin: molecular simulations of barrier lipids to design more effective noninvasive dermal and transdermal delivery systems for small molecules, biologics, and cosmetics

(2011) J. Torin Huzil et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Synthesis, Encapsulation and Antitumor Activity of New Betulin Derivatives

(2010) René Csuk et al.   ARCHIV DER PHARMAZIE

Biopharmaceutical study of nanosystems containing betulin for inhalation administration

(2010) M. V. Karlina et al.   PHARMACEUTICAL CHEMISTRY JOURNAL

Betulin and betulinic acid attenuate ethanol-induced liver stellate cell activation by inhibiting reactive oxygen species (ROS), cytokine (TNF-α, TGF-β) production and by influencing intracellular signaling

(2010) Agnieszka Szuster-Ciesielska et al.   TOXICOLOGY

Study of the aerosol fragrances of eugenol derivatives in Cananga odorata using diffuse reflectance infrared Fourier transform spectroscopy and gas chromatography

(2009) Su-Ching Kuo et al.   ANALYTICA CHIMICA ACTA

Synthesis of betulin derivatives and the determination of their relative lipophilicities using reversed-phase thin-layer chromatography

(2009) Jacek Achrem-Achremowicz et al.   BIOMEDICAL CHROMATOGRAPHY

Esters of betulin and betulinic acid with amino acids have improved water solubility and are selectively cytotoxic toward cancer cells

(2009) Malgorzata Drag-Zalesinska et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS