4.5 Article

Partial protection of Sinopharm vaccine against SARS COV2 during recent outbreak in Bahrain

Journal

MICROBIAL PATHOGENESIS
Volume 158, Issue -, Pages -

Publisher

ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.micpath.2021.105086

Keywords

Vaccines; S protein; SARS CoV 2; WHO; GCC

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The research found that receiving the Sinopharm vaccine does not provide complete protection against SARS COV 2 infection, possibly due to its inability to detect recent variations in the spike protein structure. Social gatherings were identified as the main source of transmission.
Background: In order to impart immunity against SARS COV 2 in the community, the oil rich countries of the Gulf Cooperation Council (GCC) provided citizens and expatriates with free vaccination. Different types of vaccination brands were utilized for this purpose. The purpose of this study is to determine the efficacy of the different types of vaccinations used. Methods: This is an observational analytical case study of one Bahraini family who were vaccinated with 1st, 2nd or no dose. Results: Out of 22 double dose recipients of SARS COV2 vaccine, 20 were infected. Those 20 were vaccinated against SARS COV 2 using Sinopharm, the rest (2) were in direct contact with the source but were vaccinated against SARS COV 2 using other type of vaccine. Out of 26 single dose recipients of Sinopharm vaccine, 23 were infected. The other three were not in direct contact with the infected source. Social gathering has been the main source of transmission. The infection has been mild with headache, chest pain. From 20 cases with double dose vaccinations only one had a lung infection and needed hospitalization. Out of 23 cases with single dose vaccinations 10 were hospitalized due to lung infections. All family members who were not vaccinated were infected, three were hospitalized one of which was deceased due to diabetes mellitus complications. Conlcusion: Sinopharm provides partial protection against SARS COV 2 infection. That might be due to lack of its potential to detect recent variations in the protein structure of spike(S) protein of virus.

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