Silencing STAT3 enhances sensitivity of cancer cells to doxorubicin and inhibits tumor progression

Silencing of p68 and STAT3 synergistically diminishes cancer progression

(2020) Vida Hashemi et al.   LIFE SCIENCES

Silencing of IL-6 and STAT3 by siRNA loaded hyaluronate-N,N,N-trimethyl chitosan nanoparticles potently reduces cancer cell progression

(2020) Ali Masjedi et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Codelivery of STAT3 siRNA and BV6 by carboxymethyl dextran trimethyl chitosan nanoparticles suppresses cancer cell progression

(2020) Afshin Nikkhoo et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Enhancing chemosensitivity of wild-type and drug-resistant MDA-MB-231 triple-negative breast cancer cell line to doxorubicin by silencing of STAT 3, Notch-1, and β-catenin genes

(2020) Arwa Alkaraki et al.   Breast Cancer

Napabucasin, a novel inhibitor of STAT3, inhibits growth and synergises with doxorubicin in diffuse large B-cell lymphoma

(2020) Xue Li et al.   CANCER LETTERS

Inhibition of CD73 using folate targeted nanoparticles carrying anti-CD73 siRNA potentiates anticancer efficacy of Dinaciclib

(2020) Shahin Hallaj et al.   LIFE SCIENCES

Formulation of Stattic as STAT3 inhibitor in nanostructured lipid carriers (NLCs) enhances efficacy of doxorubicin in melanoma cancer cells

(2020) Jamal Mohammadian et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Efficiency of Different Treatment Regimens Combining Anti-tumor and Anti-inflammatory Liposomes for Metastatic Breast Cancer

(2020) Jingxuan Liu et al.   AAPS PHARMSCITECH

Differential regulation of Lipocalin 2 (LCN2) in doxorubicin-resistant 4T1 triple negative breast cancer cells

(2020) Steffen K. Meurer et al.   CELLULAR SIGNALLING

Combined inhibition of CD73 and ZEB1 by Arg-Gly-Asp (RGD)-targeted nanoparticles inhibits tumor growth

(2020) Khalid Odamizil Alzamely et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Nanoparticle mediated codelivery of nifuratel and doxorubicin for synergistic anticancer therapy through STAT3 inhibition

(2020) Hailun Zheng et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Silencing of HIF-1α/CD73 axis by siRNA-loaded TAT-chitosan-spion nanoparticles robustly blocks cancer cell progression

(2020) Farnaz Hajizadeh et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Blockade of CTLA-4 increases anti-tumor response inducing potential of dendritic cell vaccine

(2020) Maryam Esmaily et al.   JOURNAL OF CONTROLLED RELEASE

Silencing adenosine A2a receptor enhances dendritic cell-based cancer immunotherapy

(2020) Ali Masjedi et al.   Nanomedicine-Nanotechnology Biology and Medicine

Codelivery of HIF-1α siRNA and Dinaciclib by Carboxylated Graphene Oxide-Trimethyl Chitosan-Hyaluronate Nanoparticles Significantly Suppresses Cancer Cell Progression

(2020) Sepideh Izadi et al.   PHARMACEUTICAL RESEARCH

Inhibition of HIF-1α/EP4 axis by hyaluronate-trimethyl chitosan-SPION nanoparticles markedly suppresses the growth and development of cancer cells

(2020) Vahid Karpisheh et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Codelivery of STAT3 and PD-L1 siRNA by hyaluronate-TAT trimethyl/thiolated chitosan nanoparticles suppresses cancer progression in tumor-bearing mice

(2020) Shima Bastaki et al.   LIFE SCIENCES

Downregulation of A2AR by siRNA loaded PEG-chitosan-lactate nanoparticles restores the T cell mediated anti-tumor responses through blockage of PKA/CREB signaling pathway

(2019) Ali Masjedi et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Downregulation of STAT3, β-Catenin, and Notch-1 by Single and Combinations of siRNA Treatment Enhance Chemosensitivity of Wild Type and Doxorubicin Resistant MCF7 Breast Cancer Cells to Doxorubicin

(2019) Walhan Alshaer et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Blockage of immune checkpoint molecules increases T‐cell priming potential of dendritic cell vaccine

(2019) Hadi Hassannia et al.   IMMUNOLOGY

The role of STAT3 in leading the crosstalk between human cancers and the immune system

(2018) Yu Wang et al.   CANCER LETTERS

STAT3 and apoptosis challenges in cancer

(2018) Nazanin Fathi et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Anti-angiogenic effects of CD73-specific siRNA-loaded nanoparticles in breast cancer-bearing mice

(2018) Ghasem Ghalamfarsa et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Targeting the IL-6/JAK/STAT3 signalling axis in cancer

(2018) Daniel E. Johnson et al.   Nature Reviews Clinical Oncology

The significant role of interleukin-6 and its signaling pathway in the immunopathogenesis and treatment of breast cancer

(2018) Ali Masjedi et al.   BIOMEDICINE & PHARMACOTHERAPY

CD73 specific siRNA loaded chitosan lactate nanoparticles potentiate the antitumor effect of a dendritic cell vaccine in 4T1 breast cancer bearing mice

(2017) Farhad Jadidi-Niaragh et al.   JOURNAL OF CONTROLLED RELEASE

Increased efficacy of a dendritic cell–based therapeutic cancer vaccine with adenosine receptor antagonist and CD73 inhibitor

(2017) Samaneh Arab et al.   TUMOR BIOLOGY

Targeting of crosstalk between tumor and tumor microenvironment by β-D mannuronic acid (M2000) in murine breast cancer model

(2017) Fatemeh Hosseini et al.   Cancer Medicine

Synthesis and characterization of a pH responsive folic acid functionalized polymeric drug delivery system

(2016) Xia Li et al.   BIOPHYSICAL CHEMISTRY

Feedback Activation of STAT3 as a Cancer Drug-Resistance Mechanism

(2016) Chengguang Zhao et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Downregulation of CD73 in 4T1 breast cancer cells through siRNA-loaded chitosan-lactate nanoparticles

(2016) Farhad Jadidi-Niaragh et al.   TUMOR BIOLOGY

Berberine Increases Doxorubicin Sensitivity by Suppressing STAT3 in Lung Cancer

(2015) Ting Zhu et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

pH-responsive drug delivery of chitosan nanoparticles as Tamoxifen carriers for effective anti-tumor activity in breast cancer cells

(2013) R. Vivek et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Microenvironmental regulation of tumor progression and metastasis

(2013) Daniela F Quail et al.   NATURE MEDICINE

CD73 promotes anthracycline resistance and poor prognosis in triple negative breast cancer

(2013) S. Loi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Doxorubicin-Loaded Nanoparticles: New Advances in Breast Cancer Therapy

(2012) Jose Prados et al.   Anti-Cancer Agents in Medicinal Chemistry

Synthesis of TAT peptide-tagged PEGylated chitosan nanoparticles for siRNA delivery targeting neurodegenerative diseases

(2012) Meenakshi Malhotra et al.   BIOMATERIALS

Reduced frequency of NKT-like cells in patients with progressive chronic lymphocytic leukemia

(2012) Farhad Jadidi-Niaragh et al.   MEDICAL ONCOLOGY

Both FA- and mPEG-conjugated chitosan nanoparticles for targeted cellular uptake and enhanced tumor tissue distribution

(2012) Zhenqing Hou et al.   Nanoscale Research Letters

Folic Acid-Conjugated Chitosan Nanoparticles Enhanced Protoporphyrin IX Accumulation in Colorectal Cancer Cells

(2010) Shu-Jyuan Yang et al.   BIOCONJUGATE CHEMISTRY

Ionically crosslinked Ad/chitosan nanocomplexes processed by electrospinning for targeted cancer gene therapy

(2010) Yeonah Park et al.   JOURNAL OF CONTROLLED RELEASE

Jnk signaling pathway-mediated regulation of Stat3 activation is linked to the development of doxorubicin resistance in cancer cell lines

(2009) Ju-Hwa Kim et al.   BIOCHEMICAL PHARMACOLOGY

PEGylated PLGA nanoparticles for the improved delivery of doxorubicin

(2009) Jason Park et al.   Nanomedicine-Nanotechnology Biology and Medicine

Polymeric nanomedicine for cancer therapy

(2007) Jae Hyung Park et al.   PROGRESS IN POLYMER SCIENCE