Thiostrepton inhibits growth and induces apoptosis by targeting FoxM1/SKP2/MTH1 axis in B-precursor acute lymphoblastic leukemia cells

FOXM1 Inhibition in Ovarian Cancer Tissue Cultures Affects Individual Treatment Susceptibility Ex Vivo

(2021) Luzie Brückner et al.   Cancers

Sanguinarine Induces Apoptosis in Papillary Thyroid Cancer Cells via Generation of Reactive Oxygen Species

(2020) Abdul Q. Khan et al.   MOLECULES

Regulation of Normal and Malignant Hematopoiesis by FBOX Ubiquitin E3 Ligases

(2020) R. Willow Hynes-Smith et al.   TRENDS IN IMMUNOLOGY

Mechanisms of MTH1 inhibition-induced DNA strand breaks: The slippery slope from the oxidized nucleotide pool to genotoxic damage

(2019) Priyamvada Rai et al.   DNA REPAIR

Curcumin Induces Apoptotic Cell Death via Inhibition of PI3-Kinase/AKT Pathway in B-Precursor Acute Lymphoblastic Leukemia

(2019) Shilpa Kuttikrishnan et al.   Frontiers in Oncology

Therapeutic targeting of the E3 ubiquitin ligase SKP2 in T-ALL

(2019) Sonia Rodriguez et al.   LEUKEMIA

Upregulation of FOXM1 in a subset of relapsed myeloma results in poor outcome

(2018) Chunyan Gu et al.   Blood Cancer Journal

Greensporone C, a Freshwater Fungal Secondary Metabolite Induces Mitochondrial-Mediated Apoptotic Cell Death in Leukemic Cell Lines

(2018) Kirti S. Prabhu et al.   Frontiers in Pharmacology

Sanguinarine suppresses growth and induces apoptosis in childhood acute lymphoblastic leukemia

(2018) Shilpa Kuttikrishnan et al.   LEUKEMIA & LYMPHOMA

Dysregulated expression of SKP2 and its role in hematological malignancies

(2017) Michal Kulinski et al.   LEUKEMIA & LYMPHOMA

Acute lymphoblastic leukemia: a comprehensive review and 2017 update

(2017) T Terwilliger et al.   Blood Cancer Journal

Acute lymphoblastic leukemia cells are sensitive to disturbances in protein homeostasis induced by proteasome deubiquitinase inhibition

(2017) Magdalena Mazurkiewicz et al.   Oncotarget

Licochalcone B induces apoptosis of human oral squamous cell carcinoma through the extrinsic- and intrinsic-signaling pathways

(2016) HANA OH et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Oncogenic Actions of SKP2 Involves Deregulation of CDK1 Turnover Mediated by FOXM1

(2016) Anand Krishnan et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Nuclear FOXM1 drives chemoresistance in AML

(2016) I Khan et al.   LEUKEMIA

Involvement of F-BOX proteins in progression and development of human malignancies

(2016) Shahab Uddin et al.   SEMINARS IN CANCER BIOLOGY

FOXM1 is overexpressed in B-acute lymphoblastic leukemia (B-ALL) and its inhibition sensitizes B-ALL cells to chemotherapeutic drugs

(2015) FRANCESCA CONSOLARO et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

FOXM1 is a therapeutic target for high-risk multiple myeloma

(2015) C Gu et al.   LEUKEMIA

Co-targeting of Cyclooxygenase-2 and FoxM1 is a viable strategy in inducing anticancer effects in colorectal cancer cells

(2015) Maqbool Ahmed et al.   Molecular Cancer

Identification of FOXM1 as a therapeutic target in B-cell lineage acute lymphoblastic leukaemia

(2015) Maike Buchner et al.   Nature Communications

Overexpression of FoxM1 offers a promising therapeutic target in diffuse large B-cell lymphoma

(2012) S. Uddin et al.   HAEMATOLOGICA

Genome-Wide Expression Analysis of Middle Eastern Colorectal Cancer Reveals FOXM1 as a Novel Target for Cancer Therapy

(2011) Shahab Uddin et al.   AMERICAN JOURNAL OF PATHOLOGY

Acute lymphoblastic leukemia and developmental biology

(2011) Elena Campos-Sanchez et al.   CELL CYCLE

FoxM1 and Its Association with Matrix Metalloproteinases (MMP) Signaling Pathway in Papillary Thyroid Carcinoma

(2011) Maqbool Ahmed et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Matrix Metalloproteinases Contribute Distinct Roles in Neuroendocrine Prostate Carcinogenesis, Metastasis, and Angiogenesis Progression

(2010) L. E. Littlepage et al.   CANCER RESEARCH

The FOXM1 transcriptional factor promotes the proliferation of leukemia cells through modulation of cell cycle progression in acute myeloid leukemia

(2010) S. Nakamura et al.   CARCINOGENESIS

Forkhead box M1 transcription factor: A novel target for cancer therapy

(2009) Zhiwei Wang et al.   CANCER TREATMENT REVIEWS

FoxM1is up-regulated in gastric cancer and its inhibition leads to cellular senescence, partially dependent onp27kip1

(2009) Jiping Zeng et al.   JOURNAL OF PATHOLOGY

FoxM1 Is a General Target for Proteasome Inhibitors

(2009) Uppoor G. Bhat et al.   PLoS One

Curcumin suppresses constitutive activation of nuclear factor-κB and requires functional Bax to induce apoptosis in Burkitt's lymphoma cell lines

(2008) Azhar R. Hussain et al.   MOLECULAR CANCER THERAPEUTICS