Exploring the genetic and epigenetic origins of juvenile myelomonocytic leukemia using newborn screening samples

Integrated molecular profiling of juvenile myelomonocytic leukemia

(2018) Norihiro Murakami et al.   BLOOD

RAS-pathway mutation patterns define epigenetic subclasses in juvenile myelomonocytic leukemia

(2017) Daniel B. Lipka et al.   Nature Communications

Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia

(2017) Elliot Stieglitz et al.   Nature Communications

DNA methylation as a potential mediator of environmental risks in the development of childhood acute lymphoblastic leukemia

(2016) Jessica A Timms et al.   Epigenomics

How I treat juvenile myelomonocytic leukemia

(2015) F. Locatelli et al.   BLOOD

The genomic landscape of juvenile myelomonocytic leukemia

(2015) Elliot Stieglitz et al.   NATURE GENETICS

Identification of DNA methylation changes atcis-regulatory elements during early steps of HSC differentiation using tagmentation-based whole genome bisulfite sequencing

(2014) Daniel B Lipka et al.   CELL CYCLE

Exome sequencing identifies secondary mutations of SETBP1 and JAK3 in juvenile myelomonocytic leukemia

(2013) Hirotoshi Sakaguchi et al.   NATURE GENETICS

Mutations in CBL occur frequently in juvenile myelomonocytic leukemia

(2009) M. L. Loh et al.   BLOOD

Quantitative assessment ofPTPN11orRASmutations at the neonatal period and during the clinical course in patients with juvenile myelomonocytic leukaemia

(2009) Kazuyuki Matsuda et al.   BRITISH JOURNAL OF HAEMATOLOGY

Mitotic recombination and compound-heterozygous mutations are predominant NF1-inactivating mechanisms in children with juvenile myelomonocytic leukemia and neurofibromatosis type 1

(2009) D. Steinemann et al.   HAEMATOLOGICA