Albendazole and Mebendazole as Anti-Parasitic and Anti-Cancer Agents: an Update

An open label, block randomized, community study of the safety and efficacy of co-administered ivermectin, diethylcarbamazine plus albendazole vs. diethylcarbamazine plus albendazole for lymphatic filariasis in India

(2021) Purushothaman Jambulingam et al.   PLoS Neglected Tropical Diseases

Albendazole Exhibits Anti-Neoplastic Actions against Gastric Cancer Cells by Affecting STAT3 and STAT5 Activation by Pleiotropic Mechanism(s)

(2021) Min Hee Yang et al.   Biomedicines

Toxocariasis of the Nervous System

(2020) Maria Meliou et al.   ACTA PARASITOLOGICA

Chitosan coated nanostructured lipid carriers for enhanced in vivo efficacy of albendazole against Trichinella spiralis

(2020) Rania K. Eid et al.   CARBOHYDRATE POLYMERS

Acute Anisakiasis: Pharmacological Evaluation of Various Drugs in an Animal Model

(2020) Magdalena Gómez-Mateos et al.   DIGESTIVE DISEASES AND SCIENCES

Eosinophilic Meningitis due to Angiostrongylus cantonensis in Europe

(2020) Frederik Federspiel et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Encephalitozoon cuniculi Genotype III Evinces a Resistance to Albendazole Treatment in both Immunodeficient and Immunocompetent Mice

(2020) Bohumil Sak et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Effect of Mass Drug Administration with a Single Dose of Albendazole on Ascaris lumbricoides and Trichuris trichiura Infection among Schoolchildren in Yangon Region, Myanmar

(2020) Jong-Yil Chai et al.   KOREAN JOURNAL OF PARASITOLOGY

Have We Forgotten the Threat Posed by Fascioliasis? A Potential Threat to Public Health

(2020) Wali KHAN et al.   Iranian Journal of Public Health

The impact of four years of semiannual treatments with albendazole alone on lymphatic filariasis and soil-transmitted helminth infections: A community-based study in the Democratic Republic of the Congo

(2020) Sébastien D. S. Pion et al.   PLoS Neglected Tropical Diseases

Imported Mansonella perstans infection in Spain

(2020) Sabino Puente et al.   Infectious Diseases of Poverty

Potential and mechanism of mebendazole for treatment and maintenance of ovarian cancer

(2020) Suganthapriya Elayapillai et al.   GYNECOLOGIC ONCOLOGY

Etiology and Outcome of Acute Liver Failure in Children—The Experience of a Single Tertiary Care Hospital from Romania

(2020) Alina Grama et al.   Children-Basel

Albendazole resistance induced in Ancylostoma ceylanicum is not due to single-nucleotide polymorphisms (SNPs) at codons 167, 198, or 200 of the beta-tubulin gene, indicating another resistance mechanism

(2019) Luis Fernando Viana Furtado et al.   PARASITOLOGY RESEARCH

Albendazole sulfoxide plasma levels and efficacy of antiparasitic treatment in patients with parenchymal neurocysticercosis

(2019) Gianfranco Arroyo et al.   CLINICAL INFECTIOUS DISEASES

Antiangiogenesis Effect of Albendazole on the Cornea

(2019) Yang Kyung Cho et al.   JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS

Pharmacokinetics, safety, and efficacy of a single co-administered dose of diethylcarbamazine, albendazole and ivermectin in adults with and without Wuchereria bancrofti infection in Côte d’Ivoire

(2019) Constant Edi et al.   PLoS Neglected Tropical Diseases

The Efficacy of Doxycycline Treatment on Mansonella perstans Infection: An Open-Label, Randomized Trial in Ghana

(2019) Linda Batsa Debrah et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Antitumor Effect of Albendazole on Cutaneous Squamous Cell Carcinoma (SCC) Cells

(2019) Qing-Ling Zhang et al.   Biomed Research International

Comparison of repeated doses of ivermectin versus ivermectin plus albendazole for treatment of onchocerciasis – a randomized open-label clinical trial

(2019) Linda Batsa Debrah et al.   CLINICAL INFECTIOUS DISEASES

Hepatotoxicity caused by mebendazole in a patient with Gilbert's syndrome

(2019) Manlio Tolomeo et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

Mebendazole as a Candidate for Drug Repurposing in Oncology: An Extensive Review of Current Literature

(2019) Guerini et al.   Cancers

Thelaziosis due to Thelazia callipaeda in Europe in the 21st century—A review

(2019) Beatriz do Vale et al.   VETERINARY PARASITOLOGY

Cysticidal activity of praziquantel-mebendazole combination: In vitro and in vivo studies

(2019) Palomares-Alonso Francisca et al.   ACTA TROPICA

Repurposing screen identifies mebendazole as a clinical candidate to synergise with docetaxel for prostate cancer treatment

(2019) Linda K. Rushworth et al.   BRITISH JOURNAL OF CANCER

Effect of dexamethasone on albendazole cysticidal activity in experimental cysticercosis by Taenia crassiceps in BALB/c mice: In vitro and in vivo evaluation

(2019) Francisca Palomares-Alonso et al.   EXPERIMENTAL PARASITOLOGY

A Hospital-Based Study of Intestinal Capillariasis in Thailand: Clinical Features, Potential Clues for Diagnosis, and Epidemiological Characteristics of 85 Patients

(2018) Lakkhana Sadaow et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Case Report: Probable Case of Spontaneous Encephalopathy Due to Loiasis and Dramatic Reduction of Loa loa Microfilariaemia with Prolonged Repeated Courses of Albendazole

(2018) Divine B. Arrey-Agbor et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Medical treatment of cystic echinococcosis: systematic review and meta-analysis

(2018) Virginia Velasco-Tirado et al.   BMC INFECTIOUS DISEASES

Eosinophilic meningitis caused by Angiostrongylus cantonensis in an infant

(2018) Mingsheng Ma et al.   MEDICINE

Gongylonema pulchrum infection in the human oral cavity: A case report and literature review

(2018) Liu Xiaodan et al.   Oral Surgery Oral Medicine Oral Pathology Oral Radiology

Repositioning of Anti-parasitic Drugs in Cyclodextrin Inclusion Complexes for Treatment of Triple-Negative Breast Cancer

(2018) Josefina Priotti et al.   AAPS PHARMSCITECH

Three Cases of Intestinal Capillariasis in Lao People’s Democratic Republic

(2018) Phonepasong Soukhathammavong et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Fenbendazole acts as a moderate microtubule destabilizing agent and causes cancer cell death by modulating multiple cellular pathways

(2018) Nilambra Dogra et al.   Scientific Reports

Human gastric hyperinfection by Anisakis simplex : A severe and unusual presentation and a brief review

(2017) Teresa Baptista-Fernandes et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Treatment of larva migrans syndrome with long-term administration of albendazole

(2017) Amy Hombu et al.   JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION

Repurposing Mebendazole as a Replacement for Vincristine for the Treatment of Brain Tumors

(2017) Michelle De Witt et al.   MOLECULAR MEDICINE

Nanoformulations of albendazole as effective anticancer and antiparasite agents

(2017) Fatemeh Movahedi et al.   Nanomedicine

In vitro anti-tubulin effects of mebendazole and fenbendazole on canine glioma cells

(2017) S. R. Lai et al.   Veterinary and Comparative Oncology

Repurposing Albendazole: new potential as a chemotherapeutic agent with preferential activity against HPV-negative head and neck squamous cell cancer

(2017) Farhad Ghasemi et al.   Oncotarget

Efficacy of recommended drugs against soil transmitted helminths: systematic review and network meta-analysis

(2017) Wendelin Moser et al.   BMJ-British Medical Journal

Lymphatic pathology in asymptomatic and symptomatic children with Wuchereria bancrofti infection in children from Odisha, India and its reversal with DEC and albendazole treatment

(2017) Shantanu K. Kar et al.   PLoS Neglected Tropical Diseases

Albendazole and ivermectin for the control of soil-transmitted helminths in an area with high prevalence of Strongyloides stercoralis and hookworm in northwestern Argentina: A community-based pragmatic study

(2017) Adriana Echazú et al.   PLoS Neglected Tropical Diseases

Efficacy of recommended drugs against soil transmitted helminths: systematic review and network meta-analysis

(2017) Wendelin Moser et al.   BMJ-British Medical Journal

Reduced efficacy of albendazole against Ascaris lumbricoides in Rwandan schoolchildren

(2017) Jürgen Krücken et al.   International Journal for Parasitology-Drugs and Drug Resistance

Disseminated cysticercosis

(2016) Abdul Qavi et al.   MEDICINE

Intraocular Gongylonema Infection: First Case in Humans

(2016) Vanessa Waisberg et al.   OCULAR IMMUNOLOGY AND INFLAMMATION

Anthelmintic drug albendazole arrests human gastric cancer cells at the mitotic phase and induces apoptosis

(2016) Xuan Zhang et al.   Experimental and Therapeutic Medicine

Isothermal Diagnostic Assays for Monitoring Single Nucleotide Polymorphisms in Necator americanus Associated with Benzimidazole Drug Resistance

(2016) Nour Rashwan et al.   PLoS Neglected Tropical Diseases

Albendazole as a promising molecule for tumor control

(2016) L.S.E.P.W. Castro et al.   Redox Biology

Successful Treatment of DisseminatedAnncaliia algeraeMicrosporidial Infection With Combination Fumagillin and Albendazole

(2016) Mélissa Boileau et al.   Open Forum Infectious Diseases

A Review of Pharmacokinetic Drug–Drug Interactions with the Anthelmintic Medications Albendazole and Mebendazole

(2015) Shane Ashley Pawluk et al.   CLINICAL PHARMACOKINETICS

Case 29-2015

(2015) Steven K. Feske et al.   NEW ENGLAND JOURNAL OF MEDICINE

A 41-Year-Old Woman with Migratory Panniculitis

(2014) Edgar S. Vanegas et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Microsporidiosis Acquired Through Solid Organ Transplantation

(2014) Susan N. Hocevar et al.   ANNALS OF INTERNAL MEDICINE

Acceptance of standardized ultrasound classification, use of albendazole, and long-term follow-up in clinical management of cystic echinococcosis

(2014) Francesca Tamarozzi et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Management of chronicGiardiainfection

(2014) Angel A Escobedo et al.   Expert Review of Anti-Infective Therapy

Albendazole-induced associated acute hepatitis and bicytopenia

(2014) Nadia Ben Fredj et al.   SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES

First identification of the F200Y SNP in the β-tubulin gene linked to benzimidazole resistance in Ancylostoma caninum

(2014) Luis Fernando Viana Furtado et al.   VETERINARY PARASITOLOGY

Efficacy and Safety of Praziquantel, Tribendimidine and Mebendazole in Patients with Co-infection of Clonorchis sinensis and Other Helminths

(2014) Li-Li Xu et al.   PLoS Neglected Tropical Diseases

Drug repositioning from bench to bedside: Tumour remission by the antihelmintic drug mebendazole in refractory metastatic colon cancer

(2013) Peter Nygren et al.   ACTA ONCOLOGICA

Combination of Albendazole and 2-Methoxyestradiol significantly improves the survival of HCT-116 tumor-bearing nude mice

(2013) Anahid Ehteda et al.   BMC CANCER

Microsporidiosis: An Unusual Endoscopic Finding

(2013) Sunil Dacha et al.   Clinical Gastroenterology and Hepatology

Repositioning of the anthelmintic drug mebendazole for the treatment for colon cancer

(2013) Peter Nygren et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Drug library screening against metronidazole-sensitive and metronidazole-resistantTrichomonas vaginalisisolates

(2013) E Brook Goodhew et al.   SEXUALLY TRANSMITTED INFECTIONS

Resolution of canine ocular thelaziosis in avermectin-sensitive Border Collies from Spain

(2013) Rafael Calero-Bernal et al.   VETERINARY PARASITOLOGY

Association between Response to Albendazole Treatment and β-Tubulin Genotype Frequencies in Soil-transmitted Helminths

(2013) Aïssatou Diawara et al.   PLoS Neglected Tropical Diseases

Gongylonema

(2012) Marco Antonio Ayala et al.   ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY

Human and Animal Dirofilariasis: the Emergence of a Zoonotic Mosaic

(2012) F. Simon et al.   CLINICAL MICROBIOLOGY REVIEWS

Low Efficacy of Single-Dose Albendazole and Mebendazole against Hookworm and Effect on Concomitant Helminth Infection in Lao PDR

(2012) Phonepasong Ayé Soukhathammavong et al.   PLoS Neglected Tropical Diseases

Epidemiology of Hookworm Infection in Kintampo North Municipality, Ghana: Patterns of Malaria Coinfection, Anemia, and Albendazole Treatment Failure

(2011) Debbie Humphries et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Chemistry and Pharmacology of Neglected Helminthic Diseases

(2011) A. Mullner et al.   CURRENT MEDICINAL CHEMISTRY

Mebendazole Monotherapy and Long-Term Disease Control in Metastatic Adrenocortical Carcinoma

(2011) Irina Dobrosotskaya et al.   Endocrine Practice

Medical management of neurocysticercosis

(2011) Osvaldo Massaiti Takayanagui et al.   EXPERT OPINION ON PHARMACOTHERAPY

First Cases of Microsporidiosis in Transplant Recipients in Spain and Review of the Literature

(2011) A. L. Galvan et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Antiparasitic mebendazole shows survival benefit in 2 preclinical models of glioblastoma multiforme

(2011) Ren-Yuan Bai et al.   NEURO-ONCOLOGY

Efficacy of Single-Dose and Triple-Dose Albendazole and Mebendazole against Soil-Transmitted Helminths and Taenia spp.: A Randomized Controlled Trial

(2011) Peter Steinmann et al.   PLoS One

Albendazole sensitizes cancer cells to ionizing radiation

(2011) Kirtesh Patel et al.   Radiation Oncology

Assessment of the Anthelmintic Efficacy of Albendazole in School Children in Seven Countries Where Soil-Transmitted Helminths Are Endemic

(2011) Jozef Vercruysse et al.   PLoS Neglected Tropical Diseases

Cutaneous Larva Migrans Complicated by Löffler Syndrome

(2010) Siew Kiang Tan et al.   ARCHIVES OF DERMATOLOGY

Severe meningoencephalomyelitis due to CNS-Toxocarosis

(2010) Oliver C. Singer et al.   JOURNAL OF NEUROLOGY

Lymphatic filariasis and onchocerciasis

(2010) Mark J Taylor et al.   LANCET

The development of albendazole for lymphatic filariasis

(2009) J. Horton   ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY

Mansonella perstans: safety and efficacy of ivermectin alone, albendazole alone and the two drugs in combination

(2009) S. M. Asio et al.   ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY

Phase I clinical trial to determine maximum tolerated dose of oral albendazole in patients with advanced cancer

(2009) Mohammad H. Pourgholami et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Gnathostomiasis, Another Emerging Imported Disease

(2009) J. S. Herman et al.   CLINICAL MICROBIOLOGY REVIEWS

Epidemiology, Diagnosis, Treatment, and Control of Trichinellosis

(2009) B. Gottstein et al.   CLINICAL MICROBIOLOGY REVIEWS

Human intestinal capillariasis: diagnosis by jejunal fluid analysis obtained at enteroscopy and reversal of subtotal villous atrophy after treatment

(2009) S. Rana et al.   ENDOSCOPY

Mebendazole in parasitic infections other than those caused by soil-transmitted helminths

(2009) R. Cañete et al.   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE

Assays to Detect β-Tubulin Codon 200 Polymorphism in Trichuris trichiura and Ascaris lumbricoides

(2009) Aissatou Diawara et al.   PLoS Neglected Tropical Diseases

Treatment-ladder and genetic characterisation of parasites in refractory giardiasis after an outbreak in Norway

(2008) K. Mørch et al.   JOURNAL OF INFECTION

Microsporidiose et toxoplasmose disséminées chez une patiente présentant une leucémie prolymphocytaire T

(2008) D. Jamet et al.   MEDECINE ET MALADIES INFECTIEUSES

Mebendazole Induces Apoptosis via Bcl-2 Inactivation in Chemoresistant Melanoma Cells

(2008) N. Doudican et al.   MOLECULAR CANCER RESEARCH

Microsporidiosis in solid organ transplant recipients: twoEnterocytozoon bieneusicases and review

(2008) F. Lanternier et al.   Transplant Infectious Disease

Tribendimidine and Albendazole for Treating Soil-Transmitted Helminths, Strongyloides stercoralis and Taenia spp.: Open-Label Randomized Trial

(2008) Peter Steinmann et al.   PLoS Neglected Tropical Diseases

Efficacy of thiabendazole, mebendazole, levamisole and ivermectin against gullet worm, Gongylonema pulchrum: In vitro and in vivo studies

(2007) Noboru Kudo et al.   VETERINARY PARASITOLOGY