IDH2 deficiency promotes mitochondrial dysfunction and dopaminergic neurotoxicity: implications for Parkinson’s disease

Mitochondrial Dysfunction in Parkinson's Disease

(2017) Jianhui Zhu et al.   JOURNAL OF ALZHEIMERS DISEASE

IDH2 deficiency promotes mitochondrial dysfunction and cardiac hypertrophy in mice

(2015) Hyeong Jun Ku et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial NADP+-dependent isocitrate dehydrogenase knockdown inhibits tumorigenicity of melanoma cells

(2014) Sung Hwan Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Attenuated mitochondrial NADP+-dependent isocitrate dehydrogenase activity induces apoptosis and hypertrophy of H9c2 cardiomyocytes

(2013) Jun Ho Lee et al.   BIOCHIMIE

Mitochondria and Programmed Cell Death in Parkinson's Disease: Apoptosis and Beyond

(2011) Celine Perier et al.   ANTIOXIDANTS & REDOX SIGNALING

Regulation of brefeldin A-induced ER stress and apoptosis by mitochondrial NADP+-dependent isocitrate dehydrogenase

(2011) Jung Lee Moon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Etiology and pathogenesis of Parkinson's disease

(2011) Anthony H. Schapira et al.   MOVEMENT DISORDERS

The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate

(2010) Patrick S. Ward et al.   CANCER CELL

Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations

(2010) Stefan Gross et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cell Death Pathways in Parkinson's Disease: Role of Mitochondria

(2009) Zhi Yao et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondrial dysfunction in Parkinson's disease

(2009) Konstanze F. Winklhofer et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Inactivation of mitochondrial NADP+-dependent isocitrate dehydrogenase by hypochlorous acid

(2008) Sin Young Park et al.   FREE RADICAL RESEARCH